ACS Publications. Most Trusted. Most Cited. Most Read
High Concentrations of Furan Fatty Acids in Organic Butter Samples from the German Market

OR SEARCH CITATIONS

My Activity
Publications

Figure 1Loading Img
Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Agric. Food Chem. 2014, 62, 34, 8740-8744
    Article

    High Concentrations of Furan Fatty Acids in Organic Butter Samples from the German Market
    Click to copy article linkArticle link copied!

    View Author Information
    Institute of Food Chemistry (170b), University of Hohenheim, Garbenstraße 28, D-70599 Stuttgart, Germany
    *(W.V.) Phone: +49 711 459 24016. Fax: +49 711 459 24377. E-mail: [email protected]
    Other Access OptionsSupporting Information (1)

    Journal of Agricultural and Food Chemistry

    Cite this: J. Agric. Food Chem. 2014, 62, 34, 8740–8744
    Click to copy citationCitation copied!
    https://doi.org/10.1021/jf502975b
    Published August 7, 2014
    Copyright © 2014 American Chemical Society
    Request reuse permissions

    Abstract

    Click to copy section linkSection link copied!
    Abstract Image

    Furan fatty acids (F-acids) are valuable antioxidants containing a furan moiety in the central part of the molecule. They occur in the lipids of different foodstuffs and plants, with grass being the main source for their presence in milk fat and butter. Because cows from organic farming receive higher portions of grass-based feed, it was tested whether organic butter samples (n = 26) contain more F-acids than conventional ones (n = 25) in Germany. For this purpose, samples were melted, and the lipid phase was separated and transesterified into methyl esters, which were enriched using silver ion chromatography and analyzed by GC-EI/MS in the selected ion monitoring (SIM) mode. Levels of F-acids in butter were higher in summer than in winter, and in both seasons, organic samples contained significantly higher levels of F-acids than conventional ones (one-way ANOVA: p < 0.001). Furthermore, the daily intake of F-acids via milk fat and other foodstuffs was calculated.

    Copyright © 2014 American Chemical Society

    Subjects

    what are subjects

    Keywords

    what are keywords

    Read this article

    To access this article, please review the available access options below.

    Get instant access

    Purchase Access

    Read this article for 48 hours. Check out below using your ACS ID or as a guest.

    Recommended

    Access through Your Institution

    You may have access to this article through your institution.

    Your institution does not have access to this content. Add or change your institution or let them know you’d like them to include access.

    Supporting Information

    Click to copy section linkSection link copied!

    Table S1: F-acid contents of all butter samples. This material is available free of charge via the Internet at http://pubs.acs.org.

    Terms & Conditions

    Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses). Permission may be obtained from ACS for other uses through requests via the RightsLink permission system: http://pubs.acs.org/page/copyright/permissions.html.

    Cited By

    Click to copy section linkSection link copied!
    Citation Statements
    Explore this article's citation statements on scite.ai
    powered by  Scite

    This article is cited by 40 publications.

    1. Franziska Müller, Vanessa Hermann-Ene, Isabell Schmidpeter, Tim Hammerschick, Walter Vetter. Furan Fatty Acids in Some 20 Fungi Species: Unique Profiles and Quantities. Journal of Agricultural and Food Chemistry 2022, 70 (39) , 12620-12628. https://doi.org/10.1021/acs.jafc.2c05100
    2. Vera Gottstein, Marco Müller, Johannes Günther, Thomas Kuballa, Walter Vetter. Direct 1H NMR Quantitation of Valuable Furan Fatty Acids in Fish Oils and Fish Oil Fractions. Journal of Agricultural and Food Chemistry 2019, 67 (42) , 11788-11795. https://doi.org/10.1021/acs.jafc.9b04711
    3. Marco Müller, Melanie Hogg, Kerstin Ulms, and Walter Vetter . Concentrations, Stability, and Isolation of the Furan Fatty Acid 9-(3-Methyl-5-pentylfuran-2-yl)-nonanoic Acid from Disposable Latex Gloves. Journal of Agricultural and Food Chemistry 2017, 65 (36) , 7919-7925. https://doi.org/10.1021/acs.jafc.7b02444
    4. Takashi Sano, Ryo Okabe, Maiko Iwahashi, Jun Imagi, Toshiro Sato, Toshiyuki Yamashita, Eiichiro Fukusaki, and Takeshi Bamba . Effect of Furan Fatty Acids and 3-Methyl-2,4-nonanedione on Light-Induced Off-Odor in Soybean Oil. Journal of Agricultural and Food Chemistry 2017, 65 (10) , 2136-2140. https://doi.org/10.1021/acs.jafc.6b05056
    5. Fei Chang, Pascal Rowart, Sonia R. Salvatore, Oren Rom, Mark Mascal, Francisco J. Schopfer. The emerging significance of furan fatty acids in food, nutrition, and potential therapeutic use. Food Chemistry 2025, 479 , 143759. https://doi.org/10.1016/j.foodchem.2025.143759
    6. Mathys Chaslin, Georges Maroun, Erwann Durand, Béatrice Bonafos, Said Assou, Jatuporn Chaiyut, Laurent Vaysse, Vincent Ferrer, Siriluck Liengprayoon, Thomas Brioche, Laurence Pessemesse, Mélanie Macart, Christelle Bertrand-Gaday, Yves-Marie Pers, Charles Coudray, Jean-Marc Brondello, François Casas, Christine Feillet-Coudray. Furan fatty acids supplementation in obese mice reverses hepatic steatosis and protects against cartilage degradation. Biomedicine & Pharmacotherapy 2025, 187 , 118072. https://doi.org/10.1016/j.biopha.2025.118072
    7. Felix Rüttler, Walter Vetter. A simple approach to predict device-specific peak widths in countercurrent chromatography. Journal of Chromatography A 2025, 1746 , 465803. https://doi.org/10.1016/j.chroma.2025.465803
    8. Camil Merheb, Sabine Gerbal-Chaloin, François Casas, Mona Diab-Assaf, Martine Daujat-Chavanieu, Christine Feillet-Coudray. Omega-3 Fatty Acids, Furan Fatty Acids, and Hydroxy Fatty Acid Esters: Dietary Bioactive Lipids with Potential Benefits for MAFLD and Liver Health. Nutrients 2025, 17 (6) , 1031. https://doi.org/10.3390/nu17061031
    9. Franziska Müller, Vanessa Bauer, Walter Vetter. Furan fatty acid amounts and their occurrence in triacylglycerols of white asparagus ( Asparagus officinalis ) from the German market. Journal of the American Oil Chemists' Society 2024, 101 (4) , 383-395. https://doi.org/10.1002/aocs.12775
    10. Tim Hammerschick, Walter Vetter. Silver ion chromatography enables the separation of 2‐methylalkylresorcinols from alkylresorcinols. Journal of Separation Science 2023, 46 (20) https://doi.org/10.1002/jssc.202300243
    11. Franziska Müller, Jürgen Conrad, Tim Hammerschick, Walter Vetter. Enrichment and structural assignment of geometric isomers of unsaturated furan fatty acids. Analytical and Bioanalytical Chemistry 2023, 415 (25) , 6333-6343. https://doi.org/10.1007/s00216-023-04908-z
    12. Laetitia Dore, Erwann Durand, Béatrice Bonafos, Jatuporn Chaiyut, Laurent Vaysse, Siriluck Liengprayoon, Sylvie Gaillet, Laurence Pessemesse, Karen Lambert, Christelle Bertrand-Gaday, Charles Coudray, Ariane Sultan, François Casas, Christine Feillet-Coudray. Preventive nutritional supplementation with furan fatty acid in a DIO mouse model increases muscle mass and reduces metabolic disorders. Biomedicine & Pharmacotherapy 2023, 164 , 114945. https://doi.org/10.1016/j.biopha.2023.114945
    13. Franziska Müller, Tim Hammerschick, Walter Vetter. Geometrical and positional isomers of unsaturated furan fatty acids in food. Lipids 2023, 58 (2) , 69-79. https://doi.org/10.1002/lipd.12364
    14. Long Xu, Hao Cheng, Marco Müller, Andrew J. Sinclair, Weifei Wang, Xuhua Guo, Walter Vetter, Yonghua Wang. Targeted quantitation of furan fatty acids in edible oils by gas chromatography/triple quadrupole tandem mass spectrometry (GC-TQ/MS). Food Chemistry 2023, 404 , 134521. https://doi.org/10.1016/j.foodchem.2022.134521
    15. Nina Wiedmaier-Czerny, Walter Vetter. LC-Orbitrap-HRMS method for analysis of traces of triacylglycerols featuring furan fatty acids. Analytical and Bioanalytical Chemistry 2023, 415 (5) , 875-885. https://doi.org/10.1007/s00216-022-04480-y
    16. Nina Wiedmaier-Czerny, Olga Blumberg, Tobias Schulz, Franziska Kemmler, Natascha Titze, Katharina Wild, Walter Vetter. Microbial incubations of 8-phenyloctanoic acid and furan fatty acids in rumen fluid. Journal of Applied Microbiology 2022, 133 (6) , 3669-3677. https://doi.org/10.1111/jam.15804
    17. Nina Wiedmaier-Czerny, Ina Hottum, Alicia Harter, Walter Vetter. Enzymatic generation and GC/MS data of triacylglycerols with furan fatty acids (FuFAs). Food Chemistry 2022, 395 , 133627. https://doi.org/10.1016/j.foodchem.2022.133627
    18. Tim Hammerschick, Walter Vetter. Online hyphenation of centrifugal partition chromatography with countercurrent chromatography (CPC-CCC) and its application to the separation of saturated alkylresorcinols. Analytical and Bioanalytical Chemistry 2022, 414 (17) , 5043-5051. https://doi.org/10.1007/s00216-022-04136-x
    19. Anna Romanotto, Jeanette Langner, Martin Sander, Franziska Müller, Walter Vetter. Furan fatty acid concentrations in tea infusions prepared from green, black, and herbal teas. Journal of the American Oil Chemists' Society 2022, 99 (6) , 501-509. https://doi.org/10.1002/aocs.12590
    20. I. Hottum, N. Wiedmaier‐Czerny, W. Vetter. Enzymatische Synthese von Triacylglyceriden mit Furanfettsäuren (FuFAs) unter Einsatz der rekombinanten Lipase von Candida antarctica. Lebensmittelchemie 2021, 75 (S2) https://doi.org/10.1002/lemi.202158044
    21. Siddabasave Gowda B. Gowda, Yusuke Minami, Divyavani Gowda, Daisuke Furuko, Hitoshi Chiba, Shu-Ping Hui. Lipidomic analysis of non-esterified furan fatty acids and fatty acid compositions in dietary shellfish and salmon by UHPLC/LTQ-Orbitrap-MS. Food Research International 2021, 144 , 110325. https://doi.org/10.1016/j.foodres.2021.110325
    22. Tim Hammerschick, Tim Wagner, Walter Vetter. Isolation of saturated alkylresorcinols from rye grains by countercurrent chromatography. Journal of Separation Science 2021, 44 (9) , 1904-1912. https://doi.org/10.1002/jssc.202001230
    23. Katherine Alvarado, Erwann Durand, Laurent Vaysse, Siriluck Liengprayoon, Sylvie Gaillet, Charles Coudray, François Casas, Christine Feillet-Coudray. Effets bénéfiques potentiels des acides gras furaniques, des lipides alimentaires bioactifs. Cahiers de Nutrition et de Diététique 2021, 56 (2) , 117-125. https://doi.org/10.1016/j.cnd.2021.01.006
    24. Charles Coudray, Erwann Durand, Laurence Balas, Ariane Sultan, François Casas, Christine Feillet-Coudray. Potential favourable health effects of some dietary uncommon fatty acids. OCL 2021, 28 , 41. https://doi.org/10.1051/ocl/2021028
    25. Tim Hammerschick, Tim Wagner, Walter Vetter. Countercurrent chromatographic fractionation followed by gas chromatography/mass spectrometry identification of alkylresorcinols in rye. Analytical and Bioanalytical Chemistry 2020, 412 (30) , 8417-8430. https://doi.org/10.1007/s00216-020-02980-3
    26. Sara Limbo, Luisa Pellegrino, Paolo D'Incecco, Serena Gobbi, Veronica Rosi, Daniela Fracassetti. Storage of pasteurized milk in clear PET bottles combined with light exposure on a retail display case: A possible strategy to define the shelf life and support a recyclable packaging. Food Chemistry 2020, 329 , 127116. https://doi.org/10.1016/j.foodchem.2020.127116
    27. Monise Helen Masuchi Buscato, Franziska Müller, Walter Vetter, Jochen Weiss, Hanna Salminen. Furan fatty acids in enriched ω-3 fish oil: Oxidation kinetics with and without added monomethyl furan fatty acid as potential natural antioxidant. Food Chemistry 2020, 327 , 127087. https://doi.org/10.1016/j.foodchem.2020.127087
    28. Franziska Müller, Melanie Hogg, Walter Vetter. Valuable furan fatty acids in soybeans and soy products. European Food Research and Technology 2020, 246 (7) , 1383-1392. https://doi.org/10.1007/s00217-020-03497-w
    29. Nina Wiedmaier‐Czerny, Marco Müller, Walter Vetter. Heart‐Cut Two‐Dimensional Countercurrent Chromatography for the Isolation of a Furan Fatty Acid Triacylglycerol from Latex Gloves and Identification of Further Lipid Compounds. Journal of the American Oil Chemists' Society 2020, 97 (5) , 463-474. https://doi.org/10.1002/aocs.12333
    30. Long Xu, Changfeng Hu, Yongguo Liu, Siming Li, Walter Vetter, Huiyong Yin, Yonghua Wang. Development of a sensitive and quantitative method for the identification of two major furan fatty acids in human plasma. Journal of Lipid Research 2020, 61 (4) , 560-569. https://doi.org/10.1194/jlr.D119000514
    31. Wei Jie Seow, Xiao-Ou Shu, Jeremy K. Nicholson, Elaine Holmes, Douglas I. Walker, Wei Hu, Qiuyin Cai, Yu-Tang Gao, Yong-Bing Xiang, Steven C. Moore, Bryan A. Bassig, Jason Y. Y. Wong, Jinming Zhang, Bu-Tian Ji, Claire L. Boulangé, Manuja Kaluarachchi, Anisha Wijeyesekera, Wei Zheng, Paul Elliott, Nathaniel Rothman, Qing Lan. Association of Untargeted Urinary Metabolomics and Lung Cancer Risk Among Never-Smoking Women in China. JAMA Network Open 2019, 2 (9) , e1911970. https://doi.org/10.1001/jamanetworkopen.2019.11970
    32. F. Müller, M. Hogg, W. Vetter. Valuable furan fatty acids in soybeans and soy products. Lebensmittelchemie 2019, 73 (S1) https://doi.org/10.1002/lemi.201951036
    33. Walter Vetter, Marco Müller, Katrin Sommer, Markus Schröder, Simon Hammann. Development of equivalent chain length (ECL) rules for lipid compounds. Journal of Chromatography A 2019, 1599 , 187-195. https://doi.org/10.1016/j.chroma.2019.04.042
    34. Gabriele Nanni, José A. Heredia-Guerrero, Uttam C. Paul, Silvia Dante, Gianvito Caputo, Claudio Canale, Athanassia Athanassiou, Despina Fragouli, Ilker S. Bayer. Poly(furfuryl alcohol)-Polycaprolactone Blends. Polymers 2019, 11 (6) , 1069. https://doi.org/10.3390/polym11061069
    35. Judith Lauvai, Anna‐Karina Becker, Katja Lehnert, Monika Schumacher, Bettina Hieronimus, Walter Vetter, Lutz Graeve. The Furan Fatty Acid 9M5 Acts as a Partial Ligand to Peroxisome Proliferator‐Activated Receptor gamma and Enhances Adipogenesis in 3T3‐L1 Preadipocytes. Lipids 2019, 54 (5) , 277-288. https://doi.org/10.1002/lipd.12152
    36. Christine Kirres, Walter Vetter. Furan fatty acid content and homologue patterns of fresh green matrices. Journal of Food Composition and Analysis 2018, 67 , 63-69. https://doi.org/10.1016/j.jfca.2018.01.001
    37. Long Xu, Andrew J. Sinclair, Muniba Faiza, Daoming Li, Xianlin Han, Huiyong Yin, Yonghua Wang. Furan fatty acids – Beneficial or harmful to health?. Progress in Lipid Research 2017, 68 , 119-137. https://doi.org/10.1016/j.plipres.2017.10.002
    38. Walter Vetter, Kerstin Ulms, Christine Wendlinger, Jaap van Rijn. Novel non-methylated furan fatty acids in fish from a zero discharge aquaculture system. NFS Journal 2016, 2 , 8-14. https://doi.org/10.1016/j.nfs.2015.11.001
    39. Michael Englert, Kerstin Ulms, Christine Wendlinger, Walter Vetter. Isolation of a furan fatty acid from Hevea brasiliensis latex employing the combined use of pH‐zone‐refining and conventional countercurrent chromatography. Journal of Separation Science 2016, 39 (3) , 490-495. https://doi.org/10.1002/jssc.201501070
    40. Christine Wendlinger, Simon Hammann, Walter Vetter. Detailed Study of Furan Fatty Acids in Total Lipids and the Cholesteryl Ester Fraction of Fish Liver. Food Analytical Methods 2016, 9 (2) , 459-468. https://doi.org/10.1007/s12161-015-0211-x
    Download PDF
    Go to Journal of Agricultural and Food Chemistry
    Get e-Alerts
    Get e-Alerts

    Journal of Agricultural and Food Chemistry

    Cite this: J. Agric. Food Chem. 2014, 62, 34, 8740–8744
    Click to copy citationCitation copied!
    https://doi.org/10.1021/jf502975b
    Published August 7, 2014
    Copyright © 2014 American Chemical Society
    Request reuse permissions

    Article Views

    917

    Altmetric

    -

    Citations

    40
    Learn about these metrics

    Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.

    Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.

    The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated.