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Discovery of a Novel, Potent, and Orally Active Nonpeptide Antagonist of the Human Luteinizing Hormone-Releasing Hormone (LHRH) Receptor

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Discovery Research Division, Takeda Chemical Industries, Ltd., 10 Wadai Tsukuba, Ibaraki 300-4293, Japan, and Pharmaceutical Research Division, Takeda Chemical Industries, Ltd., 17-85 Jusohonmachi 2-chome Yodogawa-ku, Osaka 532-8686, Japan
Cite this: J. Med. Chem. 1998, 41, 22, 4190–4195
Publication Date (Web):October 7, 1998
https://doi.org/10.1021/jm9803673
Copyright © 1998 American Chemical Society

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     Discovery Research Division.

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     To whom correspondence should be addressed.

     Pharmaceutical Research Division.

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