ACS Publications. Most Trusted. Most Cited. Most Read
Water Dispersal and Functionalization of Hydrophobic Iron Oxide Nanoparticles with Lipid-Modified Poly(amidoamine) Dendrimers

OR SEARCH CITATIONS

My Activity
Publications

Figure 1Loading Img
Download Hi-Res ImageDownload to MS-PowerPointCite This:Langmuir 2013, 29, 35, 10973-10979
    Letter

    Water Dispersal and Functionalization of Hydrophobic Iron Oxide Nanoparticles with Lipid-Modified Poly(amidoamine) Dendrimers
    Click to copy article linkArticle link copied!

    View Author Information
    † Istituto Italiano di Tecnologia, Center for Nanotechnology Innovation @NEST, Piazza San Silvestro 12, 56127 Pisa, Italy
    ‡ Institute for Complex Molecular Systems and Laboratory of Macromolecular and Organic Chemistry, Eindhoven University of Technology, P.O. Box 513, 5600 MB, Eindhoven, The Netherlands
    § INSTM and Department of Chemistry, University of Florence, via della Lastruccia 3, 50019 Sesto F. no, Firenze, Italy
    *E-mail: [email protected]. Phone: +39 050 509119. Fax: +39 050 509.
    Other Access OptionsSupporting Information (1)

    Langmuir

    Cite this: Langmuir 2013, 29, 35, 10973–10979
    Click to copy citationCitation copied!
    https://doi.org/10.1021/la400791a
    Published May 30, 2013
    Copyright © 2013 American Chemical Society
    Request reuse permissions

    Abstract

    Click to copy section linkSection link copied!
    Abstract Image

    A novel and facile method for water dispersal of hydrophobic iron oxide nanoparticles based on the amphiphilic PAMAM-C12 dendrimer is described. Stable and highly concentrated water dispersions of multifunctional magnetic nanoparticles were obtained with this single-step approach, and showed interesting relaxometric properties for MRI applications. Importantly, this method does not require substitution of the native hydrophobic capping under nonmild reaction conditions, thus preserving the structural and magnetic properties of the nanoparticles, and extending the possibility of conjugation with thermally labile groups.

    Copyright © 2013 American Chemical Society

    Subjects

    what are subjects

    Read this article

    To access this article, please review the available access options below.

    Get instant access

    Purchase Access

    Read this article for 48 hours. Check out below using your ACS ID or as a guest.

    Recommended

    Access through Your Institution

    You may have access to this article through your institution.

    Your institution does not have access to this content. Add or change your institution or let them know you’d like them to include access.

    Supporting Information

    Click to copy section linkSection link copied!

    Detailed experimental procedures. TEM and DLS size distribution. Details of relaxometric measurements. This material is available free of charge via the Internet at http://pubs.acs.org.

    Terms & Conditions

    Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses). Permission may be obtained from ACS for other uses through requests via the RightsLink permission system: http://pubs.acs.org/page/copyright/permissions.html.

    Cited By

    Click to copy section linkSection link copied!
    Citation Statements
    Explore this article's citation statements on scite.ai
    powered by  Scite

    This article is cited by 25 publications.

    1. Federica Crippa, Laura Rodriguez-Lorenzo, Xiao Hua, Bart Goris, Sara Bals, José S. Garitaonandia, Sandor Balog, David Burnand, Ann M. Hirt, Laetitia Haeni, Marco Lattuada, Barbara Rothen-Rutishauser, Alke Petri-Fink. Phase Transformation of Superparamagnetic Iron Oxide Nanoparticles via Thermal Annealing: Implications for Hyperthermia Applications. ACS Applied Nano Materials 2019, 2 (7) , 4462-4470. https://doi.org/10.1021/acsanm.9b00823
    2. Na Li, María Echeverría, Sergio Moya, Jaime Ruiz, and Didier Astruc . “Click” Synthesis of Nona-PEG-branched Triazole Dendrimers and Stabilization of Gold Nanoparticles That Efficiently Catalyze p-Nitrophenol Reduction. Inorganic Chemistry 2014, 53 (13) , 6954-6961. https://doi.org/10.1021/ic500861f
    3. Salim Albukhaty, Ghassan M. Sulaiman, Hassan Al-Karagoly, Hamdoon A. Mohammed, Abeer S. Hassan, Abdulaziz Arif A. Alshammari, Adel M. Ahmad, Raed Madhi, Faizah A. Almalki, Khawla S. Khashan, Majid S. Jabir, Mohammad Yusuf, Zaidon T. Al-aqbi, P. Sasikumar, Riaz A. Khan. Iron oxide nanoparticles: The versatility of the magnetic and functionalized nanomaterials in targeting drugs, and gene deliveries with effectual magnetofection. Journal of Drug Delivery Science and Technology 2024, 99 , 105838. https://doi.org/10.1016/j.jddst.2024.105838
    4. Salma Habib, Mohammed Talhami, Amani Hassanein, Elsadig Mahdi, Maryam AL-Ejji, Mohammad K. Hassan, Ali Altaee, Probir Das, Alaa H. Hawari. Advances in functionalization and conjugation mechanisms of dendrimers with iron oxide magnetic nanoparticles. Nanoscale 2024, 46 https://doi.org/10.1039/D4NR01376J
    5. Marieme Kacem, Nadia Katir, Abdellatif Essoumhi, Mohammed Sajieddine, Abdelkrim El Kadib. Investigating the growth, thermal expansion and dispersion of iron oxide in presence of nanostructured siloxane containing hydrophobic PDMS-like segments. Journal of Sol-Gel Science and Technology 2023, 107 (3) , 783-793. https://doi.org/10.1007/s10971-023-06152-4
    6. Deepshikha Shahdeo, Akanksha Roberts, Veerbhan Kesarwani, Milena Horvat, Raghuraj Singh Chouhan, Sonu Gandhi. Polymeric biocompatible iron oxide nanoparticles labeled with peptides for imaging in ovarian cancer. Bioscience Reports 2022, 42 (2) https://doi.org/10.1042/BSR20212622
    7. Paola Parlanti, Adriano Boni, Giovanni Signore, Melissa Santi. Targeted Dendrimer-Coated Magnetic Nanoparticles for Selective Delivery of Therapeutics in Living Cells. Molecules 2020, 25 (9) , 2252. https://doi.org/10.3390/molecules25092252
    8. Kecan Lin, Yanbing Cao, Dongye Zheng, Qin Li, Hui Liu, Peiwen Yu, Jiong Li, Yanan Xue, Ming Wu. Facile phase transfer of hydrophobic Fe 3 O 4 @Cu 2−x S nanoparticles by red blood cell membrane for MRI and phototherapy in the second near-infrared window. Journal of Materials Chemistry B 2020, 8 (6) , 1202-1211. https://doi.org/10.1039/C9TB02766A
    9. Xueqin Wang, Fan Ouyang, Liuqing Cui, Tiandi Xiong, Xinglei Guan, Yuqi Guo, Shaofeng Duan. Surface coating–modulated peroxidase-like activity of maghemite nanoparticles for a chromogenic analysis of cholesterol. Journal of Nanoparticle Research 2019, 21 (10) https://doi.org/10.1007/s11051-019-4662-7
    10. Mihail Iacob, Carmen Racles, Mihaela Dascalu, Codrin Tugui, Vasile Lozan, Maria Cazacu. Nanomaterials Developed by Processing Iron Coordination Compounds for Biomedical Application. Journal of Nanomaterials 2019, 2019 , 1-14. https://doi.org/10.1155/2019/2592974
    11. Wajeeh Kachi, Ahmed Majeed Al-Shammari, Israa G. Zainal. Cobalt Ferrite Nanoparticles: Preparation, characterization and salinized with 3-aminopropyl triethoxysilane. Energy Procedia 2019, 157 , 1353-1365. https://doi.org/10.1016/j.egypro.2018.11.300
    12. . Nanomaterials. 2018, 5-78. https://doi.org/10.1002/9781119418962.ch2
    13. Israa G. Zainal, Ahmed Majeed Al-Shammari, Wjeah Kachi. Characterization of the modified nickel-zinc ferrite nanoparticles coated with APTES by salinization reaction. 2018, 030008. https://doi.org/10.1063/1.5039195
    14. Jingchao Li, Shige Wang, Xiangyang Shi, Mingwu Shen. Aqueous-phase synthesis of iron oxide nanoparticles and composites for cancer diagnosis and therapy. Advances in Colloid and Interface Science 2017, 249 , 374-385. https://doi.org/10.1016/j.cis.2017.02.009
    15. Jia Yang, Lu Fan, Yanhong Xu, Jindong Xia. Iron oxide nanoparticles with different polymer coatings for photothermal therapy. Journal of Nanoparticle Research 2017, 19 (10) https://doi.org/10.1007/s11051-017-4031-3
    16. A. Boni, A. M. Basini, L. Capolupo, C. Innocenti, M. Corti, M. Cobianchi, F. Orsini, A. Guerrini, C. Sangregorio, A. Lascialfari. Optimized PAMAM coated magnetic nanoparticles for simultaneous hyperthermic treatment and contrast enhanced MRI diagnosis. RSC Advances 2017, 7 (70) , 44104-44111. https://doi.org/10.1039/C7RA07589H
    17. Marlene Branca, Mahmoud Ibrahim, Diana Ciuculescu, Karine Philippot, Catherine Amiens. Water Transfer of Hydrophobic Nanoparticles: Principles and Methods. 2016, 1279-1311. https://doi.org/10.1007/978-3-319-15338-4_29
    18. Ehsan Mohammadifar, Ali Nemati Kharat, Mohsen Adeli. Polyamidoamine and polyglycerol; their linear, dendritic and linear–dendritic architectures as anticancer drug delivery systems. Journal of Materials Chemistry B 2015, 3 (19) , 3896-3921. https://doi.org/10.1039/C4TB02133A
    19. A. Boni, G. Bardi, A. Bertero, V. Cappello, M. Emdin, A. Flori, M. Gemmi, C. Innocenti, L. Menichetti, C. Sangregorio, S. Villa, V. Piazza. Design and optimization of lipid-modified poly(amidoamine) dendrimer coated iron oxide nanoparticles as probes for biomedical applications. Nanoscale 2015, 7 (16) , 7307-7317. https://doi.org/10.1039/C5NR01148E
    20. Shenghua Ma, Daming Yong, Ying Zhang, Xuejing Wang, Xiaojun Han. A Universal Approach for the Reversible Phase Transfer of Hydrophilic Nanoparticles. Chemistry – A European Journal 2014, 20 (47) , 15580-15586. https://doi.org/10.1002/chem.201404417
    21. Fernando Herranz, Beatriz Salinas, Hugo Groult, Juan Pellico, Ana Lechuga-Vieco, Riju Bhavesh, J. Ruiz-Cabello. Superparamagnetic Nanoparticles for Atherosclerosis Imaging. Nanomaterials 2014, 4 (2) , 408-438. https://doi.org/10.3390/nano4020408
    22. Carmen Racles, Mihai Iacob, Maria Butnaru, Liviu Sacarescu, Maria Cazacu. Aqueous dispersion of metal oxide nanoparticles, using siloxane surfactants. Colloids and Surfaces A: Physicochemical and Engineering Aspects 2014, 448 , 160-168. https://doi.org/10.1016/j.colsurfa.2014.02.029
    23. , , , Adriano Boni, Mauro Gemmi, Claudia Innocenti, Giuseppe Bardi, Alice Bertero, Giovanni Signore, Angelo Bifone. Lipid-modified dendrimers as a tool for the design of nanoparticle-based multimodal MRI contrast agents. 2014, 895502. https://doi.org/10.1117/12.2036748
    24. Olimpia Gamucci, Alice Bertero, Mariacristina Gagliardi, Giuseppe Bardi. Biomedical Nanoparticles: Overview of Their Surface Immune-Compatibility. Coatings 2014, 4 (1) , 139-159. https://doi.org/10.3390/coatings4010139
    25. Marlene Branca, Mahmoud Ibrahim, Diana Ciuculescu, Karine Philippot, Catherine Amiens. Water Transfer of Hydrophobic Nanoparticles: Principles and Methods. 2014, 1-26. https://doi.org/10.1007/978-3-319-13188-7_29-1
    Download PDF
    Go to Langmuir
    Get e-Alerts
    Get e-Alerts

    Langmuir

    Cite this: Langmuir 2013, 29, 35, 10973–10979
    Click to copy citationCitation copied!
    https://doi.org/10.1021/la400791a
    Published May 30, 2013
    Copyright © 2013 American Chemical Society
    Request reuse permissions

    Article Views

    1686

    Altmetric

    -

    Citations

    25
    Learn about these metrics

    Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.

    Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.

    The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated.