Pyrrolidinoindoline Alkaloids from Psychotria colorata 1Click to copy article linkArticle link copied!
Abstract
Fractionation of an alkaloid extract of Psychotria colorata flowers led to the isolation of six alkaloids, identified by UV, 1D and 2D NMR, and MS as (−)-calycanthine, isocalycanthine, (+)-chimonanthine, hodgkinsine, quadrigemine C, and a new alkaloid (1), whose structure was deduced by X-ray analysis to be (8-8a),(8‘-8‘a)-tetradehydroisocalycanthine 3a(R), 3‘a(R).
*
To whom correspondence should be addressed. Tel.: 39 2 236 3469. FAX: 39 2 2364369. E-mail: [email protected].
†
Dipartimento di Chimica Organica e Industriale.
⊥
Departamento de Farmacologia.
‖
Curso de Pós-Graduação en Química.
‡
Centro per lo Studio delle Relazioni tra Struttura e Reattività del CNR. ‡ Structure Based Drug Design, Pharmacia & Upjohn.
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