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    Steaming of Ginseng at High Temperature Enhances Biological Activity
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    Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Korea, and Korean Institute of Oriental Medicine, Kang-nam gu, chung-dam dong, Seoul 135-100, Korea
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    Journal of Natural Products

    Cite this: J. Nat. Prod. 2000, 63, 12, 1702–1704
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    https://doi.org/10.1021/np990152b
    Published October 21, 2000
    Copyright © 2000 American Chemical Society and American Society of Pharmacognosy
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    Abstract

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    The present study was performed to evaluate the effect of steaming ginseng at a temperature over 100 °C on its chemical constituents and biological activities. Raw ginseng was steamed at 100, 110, and 120 °C for 2 h using an autoclave. The ginseng steamed at 120 °C was more potent in its ability to induce endothelium-dependent relaxation. Steaming the raw ginseng at 120 °C also remarkably increased the radical-scavenging activity. Ginsenosides F4, Rg3, and Rg5, which were not present in raw ginseng, were produced after steaming. Ginsenosides Rg3 and Rg5 were the most abundant ginsenosides in the ginseng steamed at 120 °C, accounting for 39% and 19% of all ginsenosides, respectively.

    Copyright © 2000 American Chemical Society and American Society of Pharmacognosy

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    †

     Seoul National University.

    ‡

     Korean Institute of Oriental Medicine.

    *

     To whom correspondence should be addressed. Tel.:  +82-2-880-7857. Fax:  +82-2-874-8928. E-mail:  [email protected].

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    Cite this: J. Nat. Prod. 2000, 63, 12, 1702–1704
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    https://doi.org/10.1021/np990152b
    Published October 21, 2000
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