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Highly Effective Synthetic Methods for Substituted 2-Arylbenzofurans Using [3,3]-Sigmatropic Rearrangement:  Short Syntheses of Stemofuran A and Eupomatenoid 6
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    Highly Effective Synthetic Methods for Substituted 2-Arylbenzofurans Using [3,3]-Sigmatropic Rearrangement:  Short Syntheses of Stemofuran A and Eupomatenoid 6
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    Kobe Pharmaceutical University, Motoyamakita, Higashinada, Kobe 658-8558, Japan
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    Organic Letters

    Cite this: Org. Lett. 2004, 6, 11, 1761–1763
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    https://doi.org/10.1021/ol049564o
    Published April 23, 2004
    Copyright © 2004 American Chemical Society

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    A new and efficient synthesis of 2-arylbenzofurans has been achieved via a route involving acylation and subsequent [3,3]-sigmatropic rearrangement of oxime ethers. Its synthetic utility is demonstrated by a short synthesis of stemofuran A and eupomatenoid 6 in which no procedure for protection of the phenolic hydroxyl groups is needed.

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    Organic Letters

    Cite this: Org. Lett. 2004, 6, 11, 1761–1763
    Click to copy citationCitation copied!
    https://doi.org/10.1021/ol049564o
    Published April 23, 2004
    Copyright © 2004 American Chemical Society

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