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Formal Total Synthesis of the Cytotoxic Marine Ascidian Alkaloid Haouamine A

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Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802
Cite this: Org. Lett. 2006, 8, 11, 2309–2312
Publication Date (Web):April 25, 2006
https://doi.org/10.1021/ol060556c
Copyright © 2006 American Chemical Society

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    Abstract

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    Described is a convergent 13-step synthesis of a pentacyclic compound which has previously been transformed into haouamine A, therefore constituting a formal total synthesis of this unique marine alkaloid.

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    Experimental procedures for the preparation of new compounds including X-ray data and copies of NMR spectra. This material is available free of charge on the Internet at http://pubs.acs.org.

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