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    Dynamic Combinatorial Libraries Constructed on Polymer Scaffolds
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    School of Chemistry, Newcastle University, Newcastle Upon Tyne NE1 7RU, U.K.
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    Organic Letters

    Cite this: Org. Lett. 2008, 10, 15, 3291–3294
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    https://doi.org/10.1021/ol8011309
    Published June 28, 2008
    Copyright © 2008 American Chemical Society
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    Abstract

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    Functionalized polymers were prepared by grafting acylhydrazides onto a polyvinylbenzaldehyde scaffold through reversible hydrazone linkages. The dynamic nature of these linkages allows the functionalized polymers to exchange and reshuffle their appendages, and the resultant mixture of polymers can be considered as a dynamic combinatorial library constructed upon a polymer scaffold. The dynamic nature of these functionalized polymers was demonstrated.

    Copyright © 2008 American Chemical Society

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    Experimental procedures, spectroscopic data for new compounds, and GPC profiles of polymers. This material is available free of charge via the Internet at http://pubs.acs.org.

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    Organic Letters

    Cite this: Org. Lett. 2008, 10, 15, 3291–3294
    Click to copy citationCitation copied!
    https://doi.org/10.1021/ol8011309
    Published June 28, 2008
    Copyright © 2008 American Chemical Society
    Request reuse permissions

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