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Microwave-Accelerated Solvent-Free Synthesis of Thioketones, Thiolactones, Thioamides, Thionoesters, and Thioflavonoids

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Department of Chemistry and Texas Research Institute for Environmental Studies (TRIES), Sam Houston State University, Huntsville, Texas 77341-2117
Cite this: Org. Lett. 1999, 1, 5, 697–700
Publication Date (Web):July 29, 1999
https://doi.org/10.1021/ol990629a
Copyright © 1999 American Chemical Society

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    Abstract

    Abstract Image

    An expeditious, solvent-free, and high yield conversion of ketones, flavones, isoflavones, lactones, amides, and esters to the corresponding thio analogues is described utilizing Lawesson's reagent in a process that circumvents the use of dry solvents and excess of the reagent.

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     To whom correspondence should be addressed at the National Risk Management Research Laboratory, U.S. Environmental Protection Agency, 26 W. Martin Luther King Dr., MS 443, Cincinnati, OH 45268.

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