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Wearable Nanoplasmonic Patch Detecting Sun/UV Exposure

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Biophotonic Nanosensors Laboratory, Centro de Investigaciones en Óptica, A. C., Loma del Bosque 115, Lomas del Campestre, León, Guanajuato, 37150, México
Instituto Tecnológico Superior de Purísima del Rincón, Blvd. del Valle 2301, Purísima del Rincón, 36413, Guanajuato, México
§ Universidad Tecnológica de Tulancingo, Camino a Ahuehuetitla 301, Las Presas, Tulancingo, 43642 Hidalgo, México
Cite this: Anal. Chem. 2017, 89, 24, 13589–13595
Publication Date (Web):November 20, 2017
https://doi.org/10.1021/acs.analchem.7b04066
Copyright © 2017 American Chemical Society
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Abstract

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Sun exposure is known to yield beneficial health outcomes, including synthesis of adequate levels of vitamin D and beneficial modulation of blood pressure, and it is a valuable factor in mental health care. However, the increasing incidence of sun/UV exposure-related illness, such as skin cancer, is seriously concerning public health authorities as well as the scientific community. Consequently, moderate sun/UV exposure is strongly recommended. A wearable nanoplasmonic patch whose original color changes upon sun exposure due to its UV-responsive capabilities that are visually detectable has been engineered. The main scaffold of this patch is made of nanopaper, which is a flexible, lightweight, optically transparent and biocompatible material. Moreover, its UV-responsive agent is based on silver nanoparticles (AgNP), whose nanoplasmonic properties and safe use in bioapplications are widely covered in the literature. As UV light can modulate the size of AgNP significantly, the nanoplasmonic properties of the AgNP-decorated nanopaper are also modulated leading to a change in color, which is readily observable upon sun exposure. This facilitates that the users can be alerted to moderate sun exposure and may prevent skin damage. Given the transparent nanoplasmonic nature of the resulting device, after 15 min of artificial sunlight exposure, the change in color of the patch was proven more observable in skins with the highest and moderate risk of developing skin cancer (skin types I, II, III, and IV) than in skin types V and VI—which are reported to tolerate relatively high levels of sun exposure safely. This low-cost wearable device is amenable to facilitating healthcare in low-resource settings using biomaterials and nanoplasmonics.

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The Supporting Information is available free of charge on the ACS Publications website at DOI: 10.1021/acs.analchem.7b04066.

  • Supplementary Figures S1–S6 (PDF)

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Cited By


This article is cited by 8 publications.

  1. Tyler R. Ray, Jungil Choi, Amay J. Bandodkar, Siddharth Krishnan, Philipp Gutruf, Limei Tian, Roozbeh Ghaffari, John A. Rogers. Bio-Integrated Wearable Systems: A Comprehensive Review. Chemical Reviews 2019, 119 (8) , 5461-5533. https://doi.org/10.1021/acs.chemrev.8b00573
  2. Robson R. Silva, Paulo A. Raymundo-Pereira, Anderson M. Campos, Deivy Wilson, Caio G. Otoni, Hernane S. Barud, Carlos A.R. Costa, Rafael R. Domeneguetti, Debora T. Balogh, Sidney J.L. Ribeiro, Osvaldo N. Oliveira Jr.. Microbial nanocellulose adherent to human skin used in electrochemical sensors to detect metal ions and biomarkers in sweat. Talanta 2020, 218 , 121153. https://doi.org/10.1016/j.talanta.2020.121153
  3. Wenyue Zou, Murali Sastry, J. Justin Gooding, Rajesh Ramanathan, Vipul Bansal. Recent Advances and a Roadmap to Wearable UV Sensor Technologies. Advanced Materials Technologies 2020, 5 (4) , 1901036. https://doi.org/10.1002/admt.201901036
  4. Tina Naghdi, Hossein Yousefi, Amir Reza Sharifi, Hamed Golmohammadi. Nanopaper-based sensors. 2020,,https://doi.org/10.1016/bs.coac.2020.02.003
  5. Leydi Francisco-Aldana, Eden Morales-Narváez. Plasmonic colored nanopaper: a potential preventive healthcare tool against threats emerging from uncontrolled UV exposure. Journal of Physics: Photonics 2019, 1 (4) , 04LT01. https://doi.org/10.1088/2515-7647/ab41aa
  6. Salomón Marquez, Eden Morales-Narváez. Nanoplasmonics in Paper-Based Analytical Devices. Frontiers in Bioengineering and Biotechnology 2019, 7 https://doi.org/10.3389/fbioe.2019.00069
  7. A. Zink, L. Tizek, M. Schielein, A. Böhner, T. Biedermann, M. Wildner. Different outdoor professions have different risks - a cross-sectional study comparing non-melanoma skin cancer risk among farmers, gardeners and mountain guides. Journal of the European Academy of Dermatology and Venereology 2018, 32 (10) , 1695-1701. https://doi.org/10.1111/jdv.15052
  8. Jessilyn Dunn, Ryan Runge, Michael Snyder. Wearables and the medical revolution. Personalized Medicine 2018, 15 (5) , 429-448. https://doi.org/10.2217/pme-2018-0044

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