Lotus Seed Resistant Starch Regulates Gut Microbiota and Increases Short-Chain Fatty Acids Production and Mineral Absorption in MiceClick to copy article linkArticle link copied!
Abstract
Lotus seed resistant starch, known as resistant starch type 3 (LRS3), was orally administered to mice to investigate its effects on the gut microbiota, short-chain fatty acids (SCFAs) production, and mineral absorption. The results showed that mice fed LRS3 displayed a lower level of gut bacterial diversity than other groups. The numbers of starch-utilizing and butyrate-producing bacteria, such as Lactobacillus and Bifidobacterium and Lachnospiraceae, Ruminococcaceae, and Clostridium, respectively, in mice increased after the administration of medium and high doses of LRS3, while those of Rikenellaceae and Porphyromonadaceae decreased. Furthermore, SCFAs and lactic acid in mice feces were affected by LRS3, and lactate was fermented to butyrate by gut microbiota. LRS3 enhanced the intestinal absorption of calcium, magnesium, and iron, and this was dependent on the type and concentration of SCFAs, especially butyrate. Thus, LRS3 promoted the production of SCFAs and mineral absorption by regulating gut microbiota in mice.
Cited By
This article is cited by 124 publications.
- Feina Gu, Ya Wen, Xinyu Hu, Huabin Liao, Chunfang He, David Julian McClements, Weichun Pan, Fuge Niu. Novel Porous Starch Granules Fabricated Using Controlled Lipase-Amylase Treatments: Application as Delivery Systems and Resistant Starches. Journal of Agricultural and Food Chemistry 2024, 72
(44)
, 24762-24775. https://doi.org/10.1021/acs.jafc.4c07759
- Zhiyun Wang, Yan Lin, Lu Liu, Baodong Zheng, Yi Zhang, Hongliang Zeng. Effect of Lotus Seed Resistant Starch on Lactic Acid Conversion to Butyric Acid Fermented by Rat Fecal Microbiota. Journal of Agricultural and Food Chemistry 2022, 70
(5)
, 1525-1535. https://doi.org/10.1021/acs.jafc.1c06000
- Lu Liu, Yongjie Lin, Suzhen Lei, Yi Zhang, Hongliang Zeng. Synergistic Effects of Lotus Seed Resistant Starch and Sodium Lactate on Hypolipidemic Function and Serum Nontargeted Metabolites in Hyperlipidemic Rats. Journal of Agricultural and Food Chemistry 2021, 69
(48)
, 14580-14592. https://doi.org/10.1021/acs.jafc.1c05993
- Haocun Kong, Luxi Yu, Zhengbiao Gu, Caiming Li, Li Cheng, Yan Hong, Zhaofeng Li. An Innovative Short-Clustered Maltodextrin as Starch Substitute for Ameliorating Postprandial Glucose Homeostasis. Journal of Agricultural and Food Chemistry 2021, 69
(1)
, 354-367. https://doi.org/10.1021/acs.jafc.0c02828
- Jing Li, Runtian Zhao, Huan Zhao, Guiyun Chen, Yuhan Jiang, Xiaoling Lyu, Tao Wu. Reduction of Aging-Induced Oxidative Stress and Activation of Autophagy by Bilberry Anthocyanin Supplementation via the AMPK–mTOR Signaling Pathway in Aged Female Rats. Journal of Agricultural and Food Chemistry 2019, 67
(28)
, 7832-7843. https://doi.org/10.1021/acs.jafc.9b02567
- Renbing Qin, Jinglin Yu, Yufang Li, Les Copeland, Shuo Wang, Shujun Wang. Structural Changes of Starch–Lipid Complexes during Postprocessing and Their Effect on In Vitro Enzymatic Digestibility. Journal of Agricultural and Food Chemistry 2019, 67
(5)
, 1530-1536. https://doi.org/10.1021/acs.jafc.8b06371
- Ali Ubeyitogullari, Sandrayee Brahma, Devin J. Rose, Ozan N. Ciftci. In Vitro Digestibility of Nanoporous Wheat Starch Aerogels. Journal of Agricultural and Food Chemistry 2018, 66
(36)
, 9490-9497. https://doi.org/10.1021/acs.jafc.8b03231
- Fei Han, Yong Wang, Yangyang Han, Jianxin Zhao, Fenli Han, Ge Song, Ping Jiang, Haijiang Miao. Effects of Whole-Grain Rice and Wheat on Composition of Gut Microbiota and Short-Chain Fatty Acids in Rats. Journal of Agricultural and Food Chemistry 2018, 66
(25)
, 6326-6335. https://doi.org/10.1021/acs.jafc.8b01891
- Ebenezer Ola Falade, Kouadio Jean Eric-Parfait Kouamé, Yanyun Zhu, Yunyun Zheng, Xingqian Ye. A review: Examining the effects of modern extraction techniques on functional and structural properties of cellulose and hemicellulose in Brewer's Spent Grain dietary fiber. Carbohydrate Polymers 2025, 348 , 122883. https://doi.org/10.1016/j.carbpol.2024.122883
- Hamide Parhizkari, Fatemeh Mohammadipanah, Mahshid Hodjat. Osteoinductive accelerating potential of myxobacterial secondary metabolites. The Microbe 2024, 5 , 100204. https://doi.org/10.1016/j.microb.2024.100204
- Li Jiali, Zufang Wu, Lingyi Liu, Junsi Yang, Lei Wang, Zhaofeng Li, Lianliang Liu. The research advance of resistant starch: structural characteristics, modification method, immunomodulatory function, and its delivery systems application. Critical Reviews in Food Science and Nutrition 2024, 64
(29)
, 10885-10902. https://doi.org/10.1080/10408398.2023.2230287
- Soo Jin Yu, Kwang Yeon Lee, Hyeon Gyu Lee. Impact of different organic acids on heat-moisture treated potato starch for enhancing prebiotic potential. Food Science and Biotechnology 2024, 33
(14)
, 3347-3356. https://doi.org/10.1007/s10068-024-01575-3
- Qingqing Yan, Wenjing Wang, Zhexin Fan, Baokun Li, Yijiang Wei, Renqiang Yu, Tong Pan, Ning Wang, Wenwei Lu, Zhifeng Fang. Gut microbes mediate prebiotic-like effects of resistant starch. Food Bioscience 2024, 61 , 104627. https://doi.org/10.1016/j.fbio.2024.104627
- Xinyu Zhang, Yuxin Zhang, Zifan Ye, Yuanyuan Wu, Baohong Cai, Jingwen Yang. Temperature-regulated cascade reaction for homogeneous oligo-dextran synthesis using a fusion enzyme. International Journal of Biological Macromolecules 2024, 278 , 135195. https://doi.org/10.1016/j.ijbiomac.2024.135195
- Ryuji Nagata, Naoki Fukuma, Naoto Hashimoto, Kenichiro Shimada, Yasunori Nakayama, Kyu‐Ho Han, Michihiro Fukushima. Effect of Raw and Cooked Green Bananas on Cecal Fermentation Characteristics in Rats. Starch - Stärke 2024, 76
(9-10)
https://doi.org/10.1002/star.202300180
- Siphosethu R. Dibakoane, Laura Suzanne Da Silva, Belinda Meiring, Tonna A. Anyasi, Victor Mlambo, Obiro Cuthbert Wokadala. The multifactorial phenomenon of enzymatic hydrolysis resistance in unripe banana flour and its starch: A concise review. Journal of Food Science 2024, 89
(9)
, 5185-5204. https://doi.org/10.1111/1750-3841.17270
- Vanessa Sales de Oliveira, Raniella Martins do Nascimento, Shelsea Luis Cuambe, Victor Hugo Cordeiro Rosa, Tatiana Saldanha, José Lucena Barbosa Júnior, Maria Ivone Martins Jacintho Barbosa. Green banana biomass (Musa spp.): A promising natural ingredient to improve technological and nutritional properties of food products. Food Bioscience 2024, 60 , 104342. https://doi.org/10.1016/j.fbio.2024.104342
- Heyun Song, Heng Sun, Gangqiang Dong, Hui Yang, Jia Xin, Dong Yang, Xianbao Deng, Juan Liu, Yanyan Su, Mei Yang. NnSBE1 encodes a starch branching enzyme involved in starch biosynthesis in lotus seeds. International Journal of Biological Macromolecules 2024, 291 , 135104. https://doi.org/10.1016/j.ijbiomac.2024.135104
- Mingxia Yi, Xuchong Tang, Shaoxiong Liang, Ren He, Tingting Huang, Qing Lin, Rongjun Zhang. Effect of microwave alone and microwave-assisted modification on the physicochemical properties of starch and its application in food. Food Chemistry 2024, 446 , 138841. https://doi.org/10.1016/j.foodchem.2024.138841
- Qinrui Li, Youyu Gu, Jingjing Liang, Zhixian Yang, Jiong Qin. A long journey to treat epilepsy with the gut microbiota. Frontiers in Cellular Neuroscience 2024, 18 https://doi.org/10.3389/fncel.2024.1386205
- Shuqi He, Lanxin Li, Suzhen Lei, Jinhan Su, Yi Zhang, Hongliang Zeng. Effect of lotus seed resistant starch on the bioconversion pathway of taurocholic acid by regulating the intestinal microbiota. International Journal of Biological Macromolecules 2024, 266 , 131174. https://doi.org/10.1016/j.ijbiomac.2024.131174
- Jinghua Zhang, Tiantian Su, Yuan Fan, Cheng Cheng, Lanping Xu, LiTian. Spotlight on iron overload and ferroptosis: Research progress in female infertility. Life Sciences 2024, 340 , 122370. https://doi.org/10.1016/j.lfs.2023.122370
- Kai Chen, Pinghui Wei, Meiqi Jia, Lihao Wang, Zihan Li, Zhongwei Zhang, Yuhuan Liu, Lin Shi. Research Progress in Modifications, Bioactivities, and Applications of Medicine and Food Homologous Plant Starch. Foods 2024, 13
(4)
, 558. https://doi.org/10.3390/foods13040558
- Hui Zou, Huajing Gao, Yanhong Liu, Zhiwo Zhang, Jia Zhao, Wenxuan Wang, Bo Ren, Xintong Tan. Dietary inulin alleviated constipation induced depression and anxiety-like behaviors: Involvement of gut microbiota and microbial metabolite short-chain fatty acid. International Journal of Biological Macromolecules 2024, 259 , 129420. https://doi.org/10.1016/j.ijbiomac.2024.129420
- Yuan-Wei Zhang, Yan Wu, Xiang-Fei Liu, Xiao Chen, Jia-Can Su. Targeting the gut microbiota-related metabolites for osteoporosis: The inextricable connection of gut-bone axis. Ageing Research Reviews 2024, 94 , 102196. https://doi.org/10.1016/j.arr.2024.102196
- Jinmei Li, Kaisheng Shao, Na Zhang, Jinlin Lu, Zhihong Zhang, Hua Wei. Microbiota-accessible carbohydrates enhance the biological properties and promote colonization of Lactiplantibacillus plantarum ZDY2013 in the intestinal tract of weaned rats. Food Bioscience 2024, 57 , 103499. https://doi.org/10.1016/j.fbio.2023.103499
- Jiqiang Weng, Yong Zhu, Anyan Wen, Likang Qin. Butyric acid generation from kidney beans mediated by gut microbiota based on the butyryl-CoA:acetate CoA-transferase pathway. Food Bioscience 2024, 57 , 103520. https://doi.org/10.1016/j.fbio.2023.103520
- Weiyue Zhang, Nana Zhang, Xinxin Guo, Bei Fan, Shumei Cheng, Fengzhong Wang. Potato Resistant Starch Type 1 Promotes Obesity Linked with Modified Gut Microbiota in High-Fat Diet-Fed Mice. Molecules 2024, 29
(2)
, 370. https://doi.org/10.3390/molecules29020370
- Jun Han, Jirong Wu, Xin Liu, Jianrong Shi, Jianhong Xu. Physiological effects of resistant starch and its applications in food: a review. Food Production, Processing and Nutrition 2023, 5
(1)
https://doi.org/10.1186/s43014-023-00156-x
- Meng Wang, Hao Zheng, Shuaiwei Wang, Houqiang Luo, Ziwei Li, Xianzhang Song, Hongxi Xu, Peide Li, Siyu Sun, Yan Wang, Zhenjie Yuan. Comparative analysis of changes in diarrhea and gut microbiota in Beigang pigs. Microbial Pathogenesis 2023, 185 , 106441. https://doi.org/10.1016/j.micpath.2023.106441
- Jian Yin, Li Cheng, Yan Hong, Zhaofeng Li, Caiming Li, Xiaofeng Ban, Ling Zhu, Zhengbiao Gu. A Comprehensive Review of the Effects of Glycemic Carbohydrates on the Neurocognitive Functions Based on Gut Microenvironment Regulation and Glycemic Fluctuation Control. Nutrients 2023, 15
(24)
, 5080. https://doi.org/10.3390/nu15245080
- Na Li, Hejing Wang, Huizhu Zhao, Mengyang Wang, Jin Cai, Yi Hao, Jia Yu, Yun Jiang, Xin Lü, Bianfang Liu. Cooperative interactions between
Veillonella ratti
and
Lactobacillus acidophilus
ameliorate DSS-induced ulcerative colitis in mice. Food & Function 2023, 14
(23)
, 10475-10492. https://doi.org/10.1039/D3FO03898J
- Zihang Cheng, Nannan Li, Zhining Chen, Kaikai Li, Dongling Qiao, Siming Zhao, Binjia Zhang. Ingesting retrograded rice (Oryza sativa) starch relieves high-fat diet induced hyperlipidemia in mice by altering intestinal bacteria. Food Chemistry 2023, 426 , 136540. https://doi.org/10.1016/j.foodchem.2023.136540
- Tieying Li, Zihan Rui, Letian Mao, Yashan Chang, Jing Shao, Yue Chen, Qi Han, Xuemei Sui, Nan An, Haoqiu Li, Haotian Feng, Tao Jiang, Qirong Wang. Eight Weeks of Bifidobacterium lactis BL-99 Supplementation Improves Lipid Metabolism and Sports Performance through Short-Chain Fatty Acids in Cross-Country Skiers: A Preliminary Study. Nutrients 2023, 15
(21)
, 4554. https://doi.org/10.3390/nu15214554
- Ao Sun, Hongyu Liu, Mengchi Sun, Weiguang Yang, Jiaxin Liu, Yi Lin, Xianbao Shi, Jin Sun, Linlin Liu. Emerging nanotherapeutic strategies targeting gut-X axis against diseases. Biomedicine & Pharmacotherapy 2023, 167 , 115577. https://doi.org/10.1016/j.biopha.2023.115577
- Bingbing Guo, Jingyi Zhang, Weihao Zhang, Feng Chen, Bin Liu. Gut microbiota-derived short chain fatty acids act as mediators of the gut–brain axis targeting age-related neurodegenerative disorders: a narrative review. Critical Reviews in Food Science and Nutrition 2023, 4 , 1-22. https://doi.org/10.1080/10408398.2023.2272769
- Nasir Mehmood Khan, Misbah Uddin, Ebenezer Ola Falade, Farman Ali Khan, Jian Wang, Muhammad Shafique, Reem M. Alnemari, Maram H. Abduljabbar, Shujaat Ahmad. Green Synthesis of Low-Glycemic Amylose–Lipid Nanocomposites by High-Speed Homogenization and Formulation into Hydrogel. Molecules 2023, 28
(20)
, 7154. https://doi.org/10.3390/molecules28207154
- Dan Li, Xin Wang, Jilite Wang, Mingchun Wang, Jiaping Zhou, Suwen Liu, Juan Zhao, Jing Li, Hao Wang. Structural characterization of different starch–fatty acid complexes and their effects on human intestinal microflora. Journal of Food Science 2023, 88
(8)
, 3562-3576. https://doi.org/10.1111/1750-3841.16680
- Hongliang Zeng, Shuqi He, Zixiao Xiong, Jinhan Su, Yanbo Wang, Baodong Zheng, Yi Zhang. Gut microbiota-metabolic axis insight into the hyperlipidemic effect of lotus seed resistant starch in hyperlipidemic mice. Carbohydrate Polymers 2023, 314 , 120939. https://doi.org/10.1016/j.carbpol.2023.120939
- Kirti Devi, Ruchika Maurya, Shivani Sharma, Sanjay Kumar Bhadada, Mahendra Bishnoi, Kanthi Kiran Kondepudi. Chemo-Enzymatically Modified Cereal Brans as a Modulator of Healthy Gut Bacteria: An
In-Vitro
and
In-Vivo
Study. Food Biotechnology 2023, 37
(3)
, 301-322. https://doi.org/10.1080/08905436.2023.2237136
- Ran Tu, Cheng Zhou, Wenfeng Huang, Zhengping Feng, Qiufang Zhao, Xiaofei Shi, Langjun Cui, Keke Chen. Fuzi polysaccharides improve immunity in immunosuppressed mouse models by regulating gut microbiota composition. Heliyon 2023, 9
(7)
, e18244. https://doi.org/10.1016/j.heliyon.2023.e18244
- Kai Chen, Shaoyu Wu, Yiqing Guan, Yunci Ma, Yu Huang, Xin Liu, Dongling Quan, Jingru Zhang, Lin Lv, Guohua Zhang. Changes in gut microbiota linked to a prevention of cardiac remodeling induced by hypertension in spontaneously hypertensive rats fed a pawpaw fruit diet. Heliyon 2023, 9
(5)
, e15576. https://doi.org/10.1016/j.heliyon.2023.e15576
- Xin Li, Wei Chen, Jingyi Gao, Wenjie Gao, Yi Zhang, Hongliang Zeng, Baodong Zheng. Structural changes of butyrylated lotus seed starch and its impact on the gut microbiota of rat in vitro fermentation. Food Hydrocolloids 2023, 139 , 108501. https://doi.org/10.1016/j.foodhyd.2023.108501
- Qian Xu, Rongrong Ma, Jinling Zhan, Xiaoxue Lu, Chang Liu, Yaoqi Tian. Acylated resistant starches: Changes in structural properties during digestion and their fermentation characteristics. Food Hydrocolloids 2023, 139 , 108578. https://doi.org/10.1016/j.foodhyd.2023.108578
- Xinyue Li, Meng Zhao, Zikang Ding, Xiaomei Wang, Zhongshan Zhang. C-phycocyanin ameliorates cyclophosphamide-induced liver injury and metabolic disorder through the modulation of the gut microbiota in mice. Algal Research 2023, 71 , 103093. https://doi.org/10.1016/j.algal.2023.103093
- Chuanjie Chen, Guantian Li, Yacine Hemar, Harold Corke, Fan Zhu. Physicochemical properties and molecular structure of lotus seed starch. Carbohydrate Polymers 2023, 305 , 120515. https://doi.org/10.1016/j.carbpol.2022.120515
- Peilin Chen, Lu Liu, Zirun Cheng, Yi Zhang, Baodong Zheng, Xiaoke Hu, Hongliang Zeng. Structure elucidation and in vitro rat intestinal fermentation properties of a novel sulfated glucogalactan from Porphyra haitanensis. Food Science and Human Wellness 2023, 12
(2)
, 596-606. https://doi.org/10.1016/j.fshw.2022.07.062
- Aijun Chen, Yatong Liu, Tao Zhang, Yu Xiao, Xiaoqi Xu, Zheng Xu, Hong Xu. Chain conformation, mucoadhesive properties of fucoidan in the gastrointestinal tract and its effects on the gut microbiota. Carbohydrate Polymers 2023, 304 , 120460. https://doi.org/10.1016/j.carbpol.2022.120460
- Kirti Devi, Vibhu Kumar, Vijay Kumar, Neha Mahajan, Jasleen Kaur, Shikha Sharma, Ajay Kumar, Rehan Khan, Mahendra Bishnoi, Kanthi Kiran Kondepudi. Modified cereal bran (MCB) from finger millet, kodo millet, and rice bran prevents high-fat diet-induced metabolic derangements. Food & Function 2023, 14
(3)
, 1459-1475. https://doi.org/10.1039/D2FO02095E
- Simeng Qin, Keying Zhang, Xuemei Ding, Shiping Bai, Jianping Wang, Gang Tian, Yue Xuan, Zhuowei Su, Quifeng Zeng. Microbiome-metabolomics analysis insight into the effects of dietary resistant starch on intestinal integrity. Food Chemistry 2023, 401 , 134148. https://doi.org/10.1016/j.foodchem.2022.134148
- Jiamiao Hu, Zhongjing Lin, Lanxin Li, Baodong Zheng, Hongliang Zeng, Yanbo Wang, Yi Zhang. Oral Administration of Lotus-Seed Resistant Starch Protects against Food Allergy. Foods 2023, 12
(4)
, 737. https://doi.org/10.3390/foods12040737
- Hulong Lei, Qian Du, Naisheng Lu, Xueyuan Jiang, Mingzhou Li, Dong Xia, Keren Long. Comparison of the Microbiome-Metabolome Response to Copper Sulfate and Copper Glycinate in Growing Pigs. Animals 2023, 13
(3)
, 345. https://doi.org/10.3390/ani13030345
- Mayrilyn Solo Thompson, Tan Hui Yan, Nazamid Saari, Shahrul Razid Sarbini. A review: Resistant starch, a promising prebiotic for obesity and weight management. Food Bioscience 2022, 50 , 101965. https://doi.org/10.1016/j.fbio.2022.101965
- Li Wu, Wenlong Li, Guimei Chen, Ziyi Yang, Xucong Lv, Lizhong Zheng, Jinyuan Sun, Lianzhong Ai, Baoguo Sun, Li Ni. Ameliorative effects of monascin from red mold rice on alcoholic liver injury and intestinal microbiota dysbiosis in mice. Food Bioscience 2022, 50 , 102079. https://doi.org/10.1016/j.fbio.2022.102079
- Jiayue Guo, Libo Tan, Lingyan Kong. Multiple levels of health benefits from resistant starch. Journal of Agriculture and Food Research 2022, 10 , 100380. https://doi.org/10.1016/j.jafr.2022.100380
- Ji Kang, Sijia Yin, Jie Liu, Chunrong Li, Nifei Wang, Jing Sun, Wenwen Li, Jian He, Qingbin Guo, Steve W. Cui. Fermentation models of dietary fibre in vitro and in vivo - A review. Food Hydrocolloids 2022, 131 , 107685. https://doi.org/10.1016/j.foodhyd.2022.107685
- Zhongyu Yang, David Julian McClements, Zhenlin Xu, Man Meng, Cuicui Li, Long Chen, Chao Qiu, Jie Long, Zhengyu Jin. Carbohydrate-based functional ingredients derived from starch: Current status and future prospects. Food Hydrocolloids 2022, 131 , 107729. https://doi.org/10.1016/j.foodhyd.2022.107729
- Xin Li, Wei Chen, David Mahoudjro Bodjrenou, Meihua Huang, Yi Zhang, Baodong Zheng, Hongliang Zeng. Properties of butyrylated lotus seed starch with butyryl groups at different carbon positions. Carbohydrate Polymers 2022, 294 , 119766. https://doi.org/10.1016/j.carbpol.2022.119766
- Li Wu, Kangxi Zhou, Ziyi Yang, Jiayi Li, Guimei Chen, Qi Wu, Xucong Lv, Wenlin Hu, Pingfan Rao, Lianzhong Ai, Li Ni. Monascuspiloin from Monascus-Fermented Red Mold Rice Alleviates Alcoholic Liver Injury and Modulates Intestinal Microbiota. Foods 2022, 11
(19)
, 3048. https://doi.org/10.3390/foods11193048
- Sanju Bala Dhull, Ankita Chandak, Maurice N. Collins, Sneh Punia Bangar, Prince Chawla, Ajay Singh. Lotus Seed Starch: A Novel Functional Ingredient with Promising Properties and Applications in Food—A Review. Starch - Stärke 2022, 74
(9-10)
https://doi.org/10.1002/star.202200064
- AGILA DAUKSIENE, JOLITA KLEMENTAVICIUTE, ROMAS GRUZAUSKAS, DOVILE KLUPSAITE, ELENA BARTKIENE. Effects of dietary Jerusalem artichoke (Helianthus tuberosus) tuber powder and medium/long-chain fatty acids on production performance and fatty acid profile in laying hens. The Indian Journal of Animal Sciences 2022, 90
(3)
, 428-432. https://doi.org/10.56093/ijans.v90i3.102527
- Shakuntla V Gondalia, Brooke Wymond, Bianca Benassi-Evans, Pierre Berbezy, Anthony R Bird, Damien P Belobrajdic. Substitution of Refined Conventional Wheat Flour with Wheat High in Resistant Starch Modulates the Intestinal Microbiota and Fecal Metabolites in Healthy Adults: A Randomized, Controlled Trial. The Journal of Nutrition 2022, 152
(6)
, 1426-1437. https://doi.org/10.1093/jn/nxac021
- Xu-Cong Lv, Qi Wu, Ying-Jia Cao, Yi-Chen Lin, Wei-Ling Guo, Ping-Fan Rao, Yan-Yan Zhang, You-Ting Chen, Lian-Zhong Ai, Li Ni. Ganoderic acid A from
Ganoderma lucidum
protects against alcoholic liver injury through ameliorating the lipid metabolism and modulating the intestinal microbial composition. Food & Function 2022, 13
(10)
, 5820-5837. https://doi.org/10.1039/D1FO03219D
- Jie Chen, Xin Jian Lei, Lei Wang, Yuan Ling Zhang, Dang Dang Wang, Li Chao Zhao, Tao Liu, Yun Tian Yang, Jun Hu Yao. Effects of rumen-protected leucine on production performance and starch digestion in the small intestine of lactating goats. Animal Feed Science and Technology 2022, 287 , 115270. https://doi.org/10.1016/j.anifeedsci.2022.115270
- Yu-Zhong Chen, Jia Gu, Wei-Ting Chuang, Ya-Fang Du, Lin Zhang, Meng-Lan Lu, Jia-Ying Xu, Hao-Qiu Li, Yan Liu, Hao-Tian Feng, Yun-Hong Li, Li-Qiang Qin. Slowly Digestible Carbohydrate Diet Ameliorates Hyperglycemia and Hyperlipidemia in High-Fat Diet/Streptozocin-Induced Diabetic Mice. Frontiers in Nutrition 2022, 9 https://doi.org/10.3389/fnut.2022.854725
- Divyani Panwar, Parmjit Singh Panesar, Anuradha Saini. Prebiotics and their Role in Functional Food Product Development. 2022, 233-271. https://doi.org/10.1002/9781119702160.ch11
- Surya Sudheer, Prateeksha Gangwar, Zeba Usmani, Minaxi Sharma, Vivek Kumar Sharma, Siva Sankar Sana, Fausto Almeida, Nawal Kishore Dubey, Dhananjaya Pratap Singh, Neeraj Dilbaghi, Hamid Reza Khayat Kashani, Vijai Kumar Gupta, Brahma Nand Singh, Maryam Khayatkashani, Seyed Mohammad Nabavi. Shaping the gut microbiota by bioactive phytochemicals: An emerging approach for the prevention and treatment of human diseases. Biochimie 2022, 193 , 38-63. https://doi.org/10.1016/j.biochi.2021.10.010
- Yujiao Sun, Fan Wang, Yang Liu, Yuye An, Dawei Chang, Jiankang Wang, Fei Xia, Ning Liu, Xuefeng Chen, Yungang Cao. Comparison of water- and alkali-extracted polysaccharides from Fuzhuan brick tea and their immunomodulatory effects
in vitro
and
in vivo. Food & Function 2022, 13
(2)
, 806-824. https://doi.org/10.1039/D1FO02944D
- Chenxi Wang, David Julian McClements, Aiquan Jiao, Jinpeng Wang, Zhengyu Jin, Chao Qiu. Resistant starch and its nanoparticles: Recent advances in their green synthesis and application as functional food ingredients and bioactive delivery systems. Trends in Food Science & Technology 2022, 119 , 90-100. https://doi.org/10.1016/j.tifs.2021.11.025
- Mengze Song, Hongchao Jiao, Jingpeng Zhao, Xiaojuan Wang, Haifang Li, Ping Wang, Baishun Ma, Shuhong Sun, Hai Lin. Dietary Supplementation of Calcium Propionate and Calcium Butyrate Improves Eggshell Quality of Laying Hens in the Late Phase of Production. The Journal of Poultry Science 2022, 59
(1)
, 64-74. https://doi.org/10.2141/jpsa.0200127
- Yaping Huang, Shujie Yang, Zifeng Huang, Yujie Yuan, Song Miao, Yi Zhang, Hongliang Zeng, Baodong Zheng, Kaibo Deng. Difference in the adhesion of Bifidobacterium breve to lotus seed resistant starch is attributable to its structural performance conferred by the preparation method. International Journal of Biological Macromolecules 2022, 195 , 309-316. https://doi.org/10.1016/j.ijbiomac.2021.11.210
- Mingjing Zheng, Aiqian Ye, Baodong Zheng, Yi Zhang. Impacts of Whey Protein on Digestion of Lotus Seed Starch Subjected to a Dynamic In Vitro Gastric Digestion. Food Biophysics 2021, 16
(4)
, 451-459. https://doi.org/10.1007/s11483-021-09682-y
- Chuanjie Chen, Guantian Li, Fan Zhu. A novel starch from lotus (Nelumbo nucifera) seeds: Composition, structure, properties and modifications. Food Hydrocolloids 2021, 120 , 106899. https://doi.org/10.1016/j.foodhyd.2021.106899
- Xiaogang Chen, Wenjing Sun, Baichang Xu, Enyun Wu, Yao Cui, Kaiyuan Hao, Geyin Zhang, Congcong Zhou, Yanping Xu, Jiang Li, Hongbin Si. Polysaccharides From the Roots of Millettia Speciosa Champ Modulate Gut Health and Ameliorate Cyclophosphamide-Induced Intestinal Injury and Immunosuppression. Frontiers in Immunology 2021, 12 https://doi.org/10.3389/fimmu.2021.766296
- Qing Chang, Baodong Zheng, Yi Zhang, Hongliang Zeng. A comprehensive review of the factors influencing the formation of retrograded starch. International Journal of Biological Macromolecules 2021, 186 , 163-173. https://doi.org/10.1016/j.ijbiomac.2021.07.050
- Peilin Chen, Mingyao Tong, Hongliang Zeng, Baodong Zheng, Xiaoke Hu. Structural characterization and in vitro fermentation by rat intestinal microbiota of a polysaccharide from Porphyra haitanensis. Food Research International 2021, 147 , 110546. https://doi.org/10.1016/j.foodres.2021.110546
- Wenhui Zhang, Shigang Shen, Tiange Song, Xue Chen, Aixia Zhang, Haiyang Dou. Insights into the structure and conformation of potato resistant starch (type 2) using asymmetrical flow field-flow fractionation coupled with multiple detectors. Food Chemistry 2021, 349 , 129168. https://doi.org/10.1016/j.foodchem.2021.129168
- Chi Zhang, Minyi Qiu, Ting Wang, Linglong Luo, Wenjuan Xu, Jiahui Wu, Fangyuan Zhao, Kaiyang Liu, Yuan Zhang, Xueyong Wang. Preparation, structure characterization, and specific gut microbiota properties related to anti-hyperlipidemic action of type 3 resistant starch from Canna edulis. Food Chemistry 2021, 351 , 129340. https://doi.org/10.1016/j.foodchem.2021.129340
- Xin Li, Suzhen Lei, Lu Liu, Yi Zhang, Baodong Zheng, Hongliang Zeng. Synergistic effect of lotus seed resistant starch and short-chain fatty acids on mice fecal microbiota in vitro. International Journal of Biological Macromolecules 2021, 183 , 2272-2281. https://doi.org/10.1016/j.ijbiomac.2021.06.016
- Dan Liang, Liang Zhang, Hongzhu Chen, Hong Zhang, Honghai Hu, Xiaofeng Dai. Potato resistant starch inhibits diet-induced obesity by modifying the composition of intestinal microbiota and their metabolites in obese mice. International Journal of Biological Macromolecules 2021, 180 , 458-469. https://doi.org/10.1016/j.ijbiomac.2021.02.209
- Ankita Chakravarty, Moksh Tandon, Sampan Attri, Deepak Sharma, Pinky Raigond, Gunjan Goel. Structural characteristics and prebiotic activities of resistant starch from Solanum tuberosum: Kufri Bahar, a popular Indian tuber variety. LWT 2021, 145 , 111445. https://doi.org/10.1016/j.lwt.2021.111445
- Dan Liang, Nan Li, Xiaofeng Dai, Hong Zhang, Honghai Hu. Effects of different types of potato resistant starches on intestinal microbiota and short‐chain fatty acids under
in vitro
fermentation. International Journal of Food Science & Technology 2021, 56
(5)
, 2432-2442. https://doi.org/10.1111/ijfs.14873
- Fang Liu, Anan Kong, Pengfei Fu, Qin-qin Cao, Kun-sheng Tao, Di-yi Liu, Xue-bing Wang, Zong-xi Tong, Mujeeb Ur Rehman, Shu-cheng Huang. Lactobacillus rhamnosus JYLR-005 Prevents Thiram-Induced Tibial Dyschondroplasia by Enhancing Bone-Related Growth Performance in Chickens. Probiotics and Antimicrobial Proteins 2021, 13
(1)
, 19-31. https://doi.org/10.1007/s12602-020-09670-7
- Xiuting Hu, Ming Miao. Starch. 2021, 1909-1953. https://doi.org/10.1007/978-981-15-4148-3_48
- Michihiro Fukushima. Studies on the Use of Agricultural Food Products to Improve Intestinal Environment and Function. Nippon Eiyo Shokuryo Gakkaishi 2021, 74
(1)
, 3-8. https://doi.org/10.4327/jsnfs.74.3
- Dominic Agyei, Jaison Jeevanandam, Christian Kwesi Ofotsu Dzuvor, Sharadwata Pan, Michael Kobina Danquah, Caleb Acquah, Chibuike C. Udenigwe. Novel Ingredients from Cereals. 2020, 143-175. https://doi.org/10.1002/9781119470182.ch7
- Yue Yue, Zhujun He, Yonghua Zhou, R. Paul Ross, Catherine Stanton, Jianxin Zhao, Hao Zhang, Bo Yang, Wei Chen. Lactobacillus plantarum
relieves diarrhea caused by enterotoxin-producing
Escherichia coli
through inflammation modulation and gut microbiota regulation. Food & Function 2020, 11
(12)
, 10362-10374. https://doi.org/10.1039/D0FO02670K
- Minmin Yang, Tao Yan, Meng Yu, Jie Kang, Ruoxi Gao, Peng Wang, Yuhuan Zhang, Huafeng Zhang, Lin Shi. Advances in understanding of health‐promoting benefits of medicine and food homology using analysis of gut microbiota and metabolomics. Food Frontiers 2020, 1
(4)
, 398-419. https://doi.org/10.1002/fft2.49
- Peixin Wang, Hongliang Zeng, Shaoling Lin, Zhigang Zhang, Yi Zhang, Jiamiao Hu. Anti-fatigue activities of hairtail (Trichiurus lepturus) hydrolysate in an endurance swimming mice model. Journal of Functional Foods 2020, 74 , 104207. https://doi.org/10.1016/j.jff.2020.104207
- Lijun Sun, Yueyi Wang, Ming Miao. Inhibition of α-amylase by polyphenolic compounds: Substrate digestion, binding interactions and nutritional intervention. Trends in Food Science & Technology 2020, 104 , 190-207. https://doi.org/10.1016/j.tifs.2020.08.003
- Xi-xi Wang, Xia Yu, Yu Wang, Pei-jun Li, Bao-cai Xu, Ke-zhou Cai, Cong-gui Chen. Gastrointestinal digestion and cecal fermentation of a mixed gel of lean pork meat and resistant starch in mice. Food & Function 2020, 11
(8)
, 6834-6842. https://doi.org/10.1039/D0FO01204A
- Rajnish Prakash Singh, Diana Abu Halaka, Zvi Hayouka, Oren Tirosh. High-Fat Diet Induced Alteration of Mice Microbiota and the Functional Ability to Utilize Fructooligosaccharide for Ethanol Production. Frontiers in Cellular and Infection Microbiology 2020, 10 https://doi.org/10.3389/fcimb.2020.00376
- Peilin Chen, Suzhen Lei, Yueyu Chen, Qing Chang, Yi Zhang, Xiaoke Hu, Hongliang Zeng. Structural characterization of a novel galactoglucan from Fortunella margarita and its molecular structural change following simulated digestion in vitro. Journal of Functional Foods 2020, 71 , 104024. https://doi.org/10.1016/j.jff.2020.104024
- Huicui Liu, Min Zhang, Qingyu Ma, Baoming Tian, Chenxi Nie, Zhifei Chen, Juxiu Li. Health beneficial effects of resistant starch on diabetes and obesity
via
regulation of gut microbiota: a review. Food & Function 2020, 11
(7)
, 5749-5767. https://doi.org/10.1039/D0FO00855A
- Yiming Zhou, Yun Wei, Beibei Yan, Shen Zhao, Xiaoli Zhou. Regulation of tartary buckwheat‐resistant starch on intestinal microflora in mice fed with high‐fat diet. Food Science & Nutrition 2020, 8
(7)
, 3243-3251. https://doi.org/10.1002/fsn3.1601
- Yixin Zheng, Zebin Guo, Baodong Zheng, Shaoxiao Zeng, Hongliang Zeng. Insight into the formation mechanism of lotus seed starch-lecithin complexes by dynamic high-pressure homogenization. Food Chemistry 2020, 315 , 126245. https://doi.org/10.1016/j.foodchem.2020.126245
- Wenyan Huo, Zhengping Feng, Suying Hu, Langjun Cui, Ting Qiao, Lu Dai, Peng Qi, Liguang Zhang, Yu Liu, Junzhi Li. Effects of polysaccharides from wild morels on immune response and gut microbiota composition in non-treated and cyclophosphamide-treated mice. Food & Function 2020, 11
(5)
, 4291-4303. https://doi.org/10.1039/D0FO00597E
- Fan Jiang, Chunwei Du, Wenqian Jiang, Liying Wang, Shuang-kui Du. The preparation, formation, fermentability, and applications of resistant starch. International Journal of Biological Macromolecules 2020, 150 , 1155-1161. https://doi.org/10.1016/j.ijbiomac.2019.10.124
- Suzhen Lei, Xin Li, Lu Liu, Mingjing Zheng, Qing Chang, Yi Zhang, Hongliang Zeng. Effect of lotus seed resistant starch on tolerance of mice fecal microbiota to bile salt. International Journal of Biological Macromolecules 2020, 151 , 384-393. https://doi.org/10.1016/j.ijbiomac.2020.02.197
- Jiangbin Xu, Zhen Ma, Xiaoping Li, Liu Liu, Xinzhong Hu. A more pronounced effect of type III resistant starch
vs.
type II resistant starch on ameliorating hyperlipidemia in high fat diet-fed mice is associated with its supramolecular structural characteristics. Food & Function 2020, 11
(3)
, 1982-1995. https://doi.org/10.1039/C9FO02025J
Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.
Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.
The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated.