Nickel-Catalyzed Reductive Three-Component Cross-Coupling of Butadiene with Aldehydes and Alkenyl Triflates/Bromides: Access to Skipped Dienes
- Yan XuYan XuCollege of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, People’s Republic of ChinaMore by Yan Xu
- ,
- Tong SuTong SuCollege of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, People’s Republic of ChinaMore by Tong Su
- ,
- Jie-Rui ZhangJie-Rui ZhangCollege of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, People’s Republic of ChinaMore by Jie-Rui Zhang
- ,
- Hua-Jiao DingHua-Jiao DingCollege of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, People’s Republic of ChinaMore by Hua-Jiao Ding
- ,
- Yuanji GaoYuanji GaoCollege of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, People’s Republic of ChinaMore by Yuanji Gao
- ,
- Minghui XuMinghui XuCollege of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, People’s Republic of ChinaMore by Minghui Xu
- ,
- Peng CaoPeng CaoCollege of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, People’s Republic of ChinaMore by Peng Cao
- ,
- Ping HuPing HuCollege of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, People’s Republic of ChinaMore by Ping Hu
- ,
- Bi-Qin WangBi-Qin WangCollege of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, People’s Republic of ChinaMore by Bi-Qin Wang
- , and
- Bin Chen*Bin Chen*E-mail: [email protected]College of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, People’s Republic of ChinaMore by Bin Chen
Abstract
A regio- and stereoselective nickel-catalyzed reductive three-component cross-coupling of 1,3-butadiene with aldehydes and alkenyl triflates or bromides was realized. This protocol afforded a convenient approach to the synthesis of skipped diene compounds bearing various functionals and heterocyclic groups. The utility of this reaction was also demonstrated by scale-up preparation and diverse transformations.
Cited By
This article has not yet been cited by other publications.