Calcium-Modified Silk Patch as a Next-Generation Ultrasound Coupling Medium
- Sang-Mok LeeSang-Mok LeeSchool of Electrical Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of KoreaMore by Sang-Mok Lee
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- Taemin LeeTaemin LeeSchool of Electrical Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of KoreaMore by Taemin Lee
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- Hyojung KimHyojung KimSchool of Electrical Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of KoreaMore by Hyojung Kim
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- Yehhyun JoYehhyun JoSchool of Electrical Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of KoreaMore by Yehhyun Jo
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- Myeong-Gee KimMyeong-Gee KimSchool of Electrical Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of KoreaMore by Myeong-Gee Kim
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- Subeen KimSubeen KimSchool of Electrical Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of KoreaMore by Subeen Kim
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- Hyeon-Min BaeHyeon-Min BaeSchool of Electrical Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of KoreaMore by Hyeon-Min Bae
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- Hyunjoo J. Lee*Hyunjoo J. Lee*Email: [email protected]. Phone: +82423507536.School of Electrical Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of KoreaKAIST Institute for Health Science and Technology (KIHST), Daejeon 34141, Republic of KoreaKAIST Institute for NanoCentury (KINC), Daejeon 34141, Republic of KoreaMore by Hyunjoo J. Lee
Abstract
There is an increasing interest in developing next-generation wearable ultrasound patch systems because of their wide range of applications, such as home healthcare systems and continuous monitoring systems for physiological conditions. A wearable ultrasound patch system requires a stable interface to the skin, an ultrasound coupling medium, a flexible transducer array, and miniaturized operating circuitries. In this study, we proposed a patch composed of calcium (Ca)-modified silk, which serves as both a stable interface and a coupling medium for ultrasound transducer arrays. The Ca-modified silk patch provided not only a stable and conformal interface between the epidermal ultrasound transducer and human skin with high adhesion but also offered acoustic impedance close to that of human skin. The Ca-modified silk patch was flexible and stretchable (∼400% strain) and could be attached to various materials. In addition, because the acoustic impedance of the Ca-modified silk patch was 2.15 MRayl, which was similar to that of human skin (1.99 MRayl), the ultrasound transmission loss of the proposed patch was relatively low (∼0.002 dB). We also verified the use of the Ca-modified silk patch in various ultrasound applications, including ultrasound imaging, ultrasound heating, and transcranial ultrasound stimulation for neuromodulation. The comparable performance of the Ca-modified patch to that of a commercial ultrasound gel and its durability against various environmental conditions confirmed that the Ca-modified silk patch could be a promising candidate as a coupling medium for next-generation ultrasound patch systems.
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This article is cited by 4 publications.
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