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Artificial Olfactory Signal Modulation for Detection in Changing Environments

  • Mohamed F. Hassan
    Mohamed F. Hassan
    Department of Chemistry and Department of Electrical & Computer Engineering, Dalhousie University, Halifax, Nova Scotia B3H 4R2, Canada
    Analysis and Evaluation Department, Egyptian Petroleum Research Institute, Nasr City, P.B. 11727, Cairo, Egypt
  • Kamal El-Sankary
    Kamal El-Sankary
    Department of Chemistry and Department of Electrical & Computer Engineering, Dalhousie University, Halifax, Nova Scotia B3H 4R2, Canada
  • , and 
  • Michael S. Freund*
    Michael S. Freund
    Department of Chemistry and Department of Electrical & Computer Engineering, Dalhousie University, Halifax, Nova Scotia B3H 4R2, Canada
    *Email: [email protected]
Cite this: ACS Sens. 2023, 8, 2, 527–533
Publication Date (Web):February 13, 2023
https://doi.org/10.1021/acssensors.2c02852
Copyright © 2023 American Chemical Society

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Abstract

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Animals have evolved to sense in complex environments through both modulation behavior including sniffing as well as sophisticated neural processing including memory and neuromodulation. Here, we explore thermal modulation of chemically diverse sensor arrays, where response patterns are based on partitioning of odorants across the array. The differential response patterns contain information about the chemical nature of the odorant for identification. By transitioning away from well-defined concentration modulation, traditionally used in the field, to thermal modulation, it is possible to capture both diagnostic patterns as well as intensity information in complex environments. This performance is demonstrated with carbon-black based, chemically diverse sensor arrays, that are thermally modulated with light at 25 mHz exposed to different analytes of varying concentrations.

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The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acssensors.2c02852.

  • Sensor array pattering, demonstration of chemical diversity among crosshatch sensors, system setup, impact of background temperature on sensitivity, and frequency dependent sensitivity (PDF)

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