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New Surface Capacitive Touchscreen Technology To Detect DNA

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Department of Chemical and Biomolecular Engineering (BK21+ program), Korea Advanced Institute of Science and Technology (KAIST), 291, Daehak-ro, Yuseong-gu, Daejeon 305-701, Republic of Korea
*E-mail: [email protected]. Tel: +82-42-350-3932. Fax: +82-42-350-3910.
Cite this: ACS Sens. 2016, 1, 5, 560–565
Publication Date (Web):March 11, 2016
https://doi.org/10.1021/acssensors.6b00040
Copyright © 2016 American Chemical Society

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    Abstract

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    A new surface capacitive touchscreen technology to detect DNA has been developed. In this approach, advantage is taken of the fact that a signal location is determined by the relative conductivities of touching materials at two points that are simultaneously touched. In the system, buffer and target-specific probe solutions are first applied to two separate positions on the touch panel. The target DNA sample is then applied to both positions. Based on the fact that the electrical conductivity of ssDNA is different from that of dsDNA, a hybridization taking place between the probe and target DNA can be identified by determining the location of the resulting touching signal. A mathematical treatment was employed to model the new detecting principle. By using equations derived from this treatment, the experimental results were correctly estimated. Because the new technology utilizes a simple touchscreen, it should be applicable to the development of POCT or personalized medical devices.

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    Cited By

    This article is cited by 4 publications.

    1. Sebastian Horstmann, Cassi J. Henderson, Elizabeth A.H. Hall, Ronan Daly. Capacitive touchscreen sensing - A measure of electrolyte conductivity. Sensors and Actuators B: Chemical 2021, 345 , 130318. https://doi.org/10.1016/j.snb.2021.130318
    2. Hyo Yong Kim, Jayeon Song, Ki Soo Park, Hyun Gyu Park. Simple and label-free strategy for terminal transferase assay using a personal glucose meter. Chemical Communications 2020, 56 (63) , 8912-8915. https://doi.org/10.1039/D0CC02869J
    3. Joon Young Lee, Byoung Yeon Won, Hyun Gyu Park. Label‐Free Multiplex DNA Detection Utilizing Projected Capacitive Touchscreen. Biotechnology Journal 2018, 13 (2) https://doi.org/10.1002/biot.201700362
    4. K. SAMADZAMINI, J. FROUNCHI, H. VELADI. A High Optical Transmittance and Low Cost Touch Screen without Patterning. Advances in Electrical and Computer Engineering 2017, 17 (1) , 109-114. https://doi.org/10.4316/AECE.2017.01016

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