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Anesthetics Reduce the Magnitude of the Membrane Dipole Potential. Measurements in Lipid Vesicles Using Voltage-Sensitive Spin Probes

Cite this: Biochemistry 1995, 34, 16, 5536–5543
Publication Date (Print):April 25, 1995
https://doi.org/10.1021/bi00016a027
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    Cited By

    This article is cited by 29 publications.

    1. Parijat Sarkar, Amitabha Chattopadhyay. Membrane Dipole Potential: An Emerging Approach to Explore Membrane Organization and Function. The Journal of Physical Chemistry B 2022, 126 (24) , 4415-4430. https://doi.org/10.1021/acs.jpcb.2c02476
    2. Bhagyashree D. Rao, Sandeep Shrivastava, Sreetama Pal, Amitabha Chattopadhyay. Effect of Local Anesthetics on the Organization and Dynamics of Hippocampal Membranes: A Fluorescence Approach. The Journal of Physical Chemistry B 2019, 123 (3) , 639-647. https://doi.org/10.1021/acs.jpcb.8b10232
    3. Igor Vorobyov, W.F. Drew Bennett, D. Peter Tieleman, Toby W. Allen, and Sergei Noskov . The Role of Atomic Polarization in the Thermodynamics of Chloroform Partitioning to Lipid Bilayers. Journal of Chemical Theory and Computation 2012, 8 (2) , 618-628. https://doi.org/10.1021/ct200417p
    4. Olga S. Ostroumova, Valery V. Malev, Maxim G. Ilin, and Ludmila V. Schagina . Surfactin Activity Depends on the Membrane Dipole Potential. Langmuir 2010, 26 (19) , 15092-15097. https://doi.org/10.1021/la102691y
    5. Satyavani Vemparala, Carmen Domene and Michael L. Klein . Computational Studies on the Interactions of Inhalational Anesthetics with Proteins. Accounts of Chemical Research 2010, 43 (1) , 103-110. https://doi.org/10.1021/ar900149j
    6. Jordan G. Petrov,, Tonya D. Andreeva,, Dirk G. Kurth, and, Helmuth Möhwald. Negative Dipole Potentials of Uncharged Langmuir Monolayers Due to Fluorination of the Hydrophilic Heads. The Journal of Physical Chemistry B 2005, 109 (29) , 14102-14111. https://doi.org/10.1021/jp0515028
    7. Christophe Chipot,, Michael A. Wilson, and, Andrew Pohorille. Interactions of Anesthetics with the Water−Hexane Interface. A Molecular Dynamics Study. The Journal of Physical Chemistry B 1997, 101 (5) , 782-791. https://doi.org/10.1021/jp961513o
    8. Sofna Banjarnahor, Jörg König, Renke Maas. Screening of commonly prescribed drugs for effects on the CAT1-mediated transport of l-arginine and arginine derivatives. Amino Acids 2022, 54 (7) , 1101-1108. https://doi.org/10.1007/s00726-022-03156-2
    9. Sandeep Shrivastava, Pankaj Ror, Amitabha Chattopadhyay. Effect of Local Anesthetics on Dipole Potential of Different Phase Membranes: A Fluorescence Study. The Journal of Membrane Biology 2022, 255 (2-3) , 363-369. https://doi.org/10.1007/s00232-022-00240-2
    10. George Zaki Ghali, Michael George Zaki Ghali. Effects of isoflurane on arterial blood pressure, heart rate, and phrenic nerve discharge in the decerebrate rat. International Journal of Neuroscience 2021, 131 (5) , 489-503. https://doi.org/10.1080/00207454.2020.1748623
    11. Benjamin Michael Davis, Jonathan Brenton, Sterenn Davis, Ehtesham Shamsher, Claudia Sisa, Ljuban Grgic, M. Francesca Cordeiro. Assessing anesthetic activity through modulation of the membrane dipole potential. Journal of Lipid Research 2017, 58 (10) , 1962-1976. https://doi.org/10.1194/jlr.M073932
    12. Robert A. Pearlstein, Callum J. Dickson, Viktor Hornak. Contributions of the membrane dipole potential to the function of voltage-gated cation channels and modulation by small molecule potentiators. Biochimica et Biophysica Acta (BBA) - Biomembranes 2017, 1859 (2) , 177-194. https://doi.org/10.1016/j.bbamem.2016.11.005
    13. Luca Turin, Efthimios M. C. Skoulakis, Andrew P. Horsfield. Electron spin changes during general anesthesia in Drosophila. Proceedings of the National Academy of Sciences 2014, 111 (34) https://doi.org/10.1073/pnas.1404387111
    14. Mohan Babu Boggara, Ramanan Krishnamoorti. Partitioning of Nonsteroidal Antiinflammatory Drugs in Lipid Membranes: A Molecular Dynamics Simulation Study. Biophysical Journal 2010, 98 (4) , 586-595. https://doi.org/10.1016/j.bpj.2009.10.046
    15. Juha‐Matti Alakoskela, Pavol Vitovič, Paavo K. J. Kinnunen. Screening for the Drug–Phospholipid Interaction: Correlation to Phospholipidosis. ChemMedChem 2009, 4 (8) , 1224-1251. https://doi.org/10.1002/cmdc.200900052
    16. Julien Valette, Martine Guillermier, Laurent Besret, Philippe Hantraye, Gilles Bloch, Vincent Lebon. Isoflurane Strongly Affects the Diffusion of Intracellular Metabolites, as Shown by 1 H Nuclear Magnetic Resonance Spectroscopy of the Monkey Brain. Journal of Cerebral Blood Flow & Metabolism 2007, 27 (3) , 588-596. https://doi.org/10.1038/sj.jcbfm.9600353
    17. Elena E. Pohl. Dipole Potential of Bilayer Membranes. 2005, 77-100. https://doi.org/10.1016/S1554-4516(05)01002-1
    18. Juha-Matti I. Alakoskela, Tim Söderlund, Juha M. Holopainen, Paavo K. J. Kinnunen. Dipole Potential and Head-Group Spacing Are Determinants for the Membrane Partitioning of Pregnanolone. Molecular Pharmacology 2004, 66 (1) , 161-168. https://doi.org/10.1124/mol.104.000075
    19. Matthew D. Krasowski. Contradicting a Unitary Theory of General Anesthetic Action: a History of Three Compounds from 1901 to 2001. Bulletin of Anesthesia History 2003, 21 (3) , 1-24. https://doi.org/10.1016/S1522-8649(03)50031-2
    20. Thomas J. McIntosh, Adriana Vidal, Sidney A. Simon. The energetics of peptide-lipid interactions: Modulation by interfacial dipoles and cholesterol. 2002, 309-338. https://doi.org/10.1016/S1063-5823(02)52013-5
    21. Vladimir L. Sukhorukov, Markus Kürschner, Stefan Dilsky, Thomas Lisec, Bernd Wagner, Wolfdieter A. Schenk, Roland Benz, Ulrich Zimmermann. Phloretin-Induced Changes of Lipophilic Ion Transport across the Plasma Membrane of Mammalian Cells. Biophysical Journal 2001, 81 (2) , 1006-1013. https://doi.org/10.1016/S0006-3495(01)75758-X
    22. Robert S. Cantor. Breaking the Meyer-Overton Rule: Predicted Effects of Varying Stiffness and Interfacial Activity on the Intrinsic Potency of Anesthetics. Biophysical Journal 2001, 80 (5) , 2284-2297. https://doi.org/10.1016/S0006-3495(01)76200-5
    23. Laure Koubi, Mounir Tarek, Michael L. Klein, Daphna Scharf. Distribution of Halothane in a Dipalmitoylphosphatidylcholine Bilayer from Molecular Dynamics Calculations. Biophysical Journal 2000, 78 (2) , 800-811. https://doi.org/10.1016/S0006-3495(00)76637-9
    24. Andrew Pohorille, Michael H. New, Karl Schweighofer, Michael A. Wilson. Chapter 3 Insights from Computer Simulations into the Interaction of Small Molecules with Lipid Bilayers. 1999, 49-76. https://doi.org/10.1016/S0070-2161(08)61041-2
    25. Warren S. Sandberg, Brian W. Dubois, Keith W. Miller. Chapter 10 Lipid Membrane and Ligand-Gated Ion Channels in General Anesthetic Action. 1999, 311-350. https://doi.org/10.1016/S0070-2161(08)61048-5
    26. Andrew Pohorille, Michael A Wilson, Michael H New, Christophe Chipot. Concentrations of anesthetics across the water–membrane interface; the Meyer–Overton hypothesis revisited. Toxicology Letters 1998, 100-101 , 421-430. https://doi.org/10.1016/S0378-4274(98)00216-1
    27. David S Cafiso. Dipole potentials and spontaneous curvature: membrane properties that could mediate anesthesia. Toxicology Letters 1998, 100-101 , 431-439. https://doi.org/10.1016/S0378-4274(98)00217-3
    28. Elena E. Pohl, Andrey V. Krylov, Michael Block, Peter Pohl. Changes of the membrane potential profile induced by verapamil and propranolol. Biochimica et Biophysica Acta (BBA) - Biomembranes 1998, 1373 (1) , 170-178. https://doi.org/10.1016/S0005-2736(98)00098-4
    29. Edmond I Eger, Donald D. Koblin, R. Adron Harris, Joan J. Kendig, Andrew Pohorille, Michael J. Halsey, James R. Trudell. Hypothesis. Anesthesia & Analgesia 1997, 84 (4) , 915-918. https://doi.org/10.1213/00000539-199704000-00039

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