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Identification of the cytochrome P-450 induced by macrolide antibiotics in rat liver as the glucocorticoid responsive cytochrome P-450p

Cite this: Biochemistry 1985, 24, 9, 2171–2178
Publication Date (Print):April 1, 1985
https://doi.org/10.1021/bi00330a010
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    52. Yasuna Kobayashi, Michiya Suzuki, Naomi Ohshiro, Takashi Sunagawa, Tadanori Sasaki, Takiko Oguro, Shogo Tokuyama, Toshinori Yamamoto, Takemi Yoshida. Induction and Inhibition of Cytochrome P450 and Drug-Metabolizing Enzymes by Climbazole.. Biological and Pharmaceutical Bulletin 2002, 25 (1) , 53-57. https://doi.org/10.1248/bpb.25.53
    53. Susila Sivapathasundaram, Paraskevi Magnisali, Nick G. Coldham, Laurence C. Howells, Maurice J. Sauer, Costas Ioannides. A study of the expression of the xenobiotic-metabolising cytochrome P450 proteins and of testosterone metabolism in bovine liver. Biochemical Pharmacology 2001, 62 (5) , 635-645. https://doi.org/10.1016/S0006-2952(01)00710-9
    54. Holger Rosenbrock, Christoph E. Hagemeyer, Margarethe Ditter, Rolf Knoth, Benedict Volk. Identification, induction and localization of cytochrome P450s of the 3A-subfamily in mouse brain. Neurotoxicity Research 2001, 3 (4) , 339-349. https://doi.org/10.1007/BF03033195
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    56. P. Kozlik, H. R. Ha, B. Stieger, L. Bigler, F. Follath. Metabolism of amiodarone (Part III): identification of rabbit cytochrome P450 isoforms involved in the hydroxylation of mono- N -desethylamiodarone. Xenobiotica 2001, 31 (5) , 239-248. https://doi.org/10.1080/00498250110046442
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    58. Ding Dai, Re Bai, Ernest Hodgson, Randy L. Rose. Cloning, sequencing, heterologous expression, and characterization of murine cytochrome P450 3a25*(Cyp3a25), a testosterone 6β‐hydroxylase. Journal of Biochemical and Molecular Toxicology 2001, 15 (2) , 90-99. https://doi.org/10.1002/jbt.4
    59. Delphine Haouzi, Mounia Lekéhal, Alain Moreau, Claude Moulis, Gérard Feldmann, Marie-Anne Robin, Philippe Lettéron, Daniel Fau, Dominique Pessayre. Cytochrome P450–generated reactive metabolites cause mitochondrial permeability transition, caspase activation, and apoptosis in rat hepatocytes. Hepatology 2000, 32 (2) , 303-311. https://doi.org/10.1053/jhep.2000.9034
    60. Tsutomu Sakuma, Masae Takai, Yusuke Endo, Masami Kuroiwa, Ayako Ôhara, Kanokwan Jarukamjorn, Rieko Honma, Nobuo Nemoto. A Novel Female-Specific Member of the CYP3A Gene Subfamily in the Mouse Liver. Archives of Biochemistry and Biophysics 2000, 377 (1) , 153-162. https://doi.org/10.1006/abbi.2000.1747
    61. Edward L. LeCluyse, Ajay Madan, Geraldine Hamilton, Kathy Carroll, Ryan DeHaan, Andrew Parkinson. Expression and regulation of cytochrome P450 enzymes in primary cultures of human hepatocytes. Journal of Biochemical and Molecular Toxicology 2000, 14 (4) , 177-188. https://doi.org/10.1002/(SICI)1099-0461(2000)14:4<177::AID-JBT1>3.0.CO;2-4
    62. Eva Hadašová, Zuzana Charvátová, Kateřina Nerušilová, Marie Hyksová, Olga Zelenková. Influence of pretreatment with immunosuppressants on O-demethylation of dextromethorphan in isolated perfused rat liver. Experimental and Toxicologic Pathology 1999, 51 (4-5) , 330-334. https://doi.org/10.1016/S0940-2993(99)80016-5
    63. Katy Kuo Korsmeyer, Suzanne Davoll, Maria Emilia Figueiredo-Pereira, Maria Almira Correia. Proteolytic Degradation of Heme-Modified Hepatic Cytochromes P450: A Role for Phosphorylation, Ubiquitination, and the 26S Proteasome?. Archives of Biochemistry and Biophysics 1999, 365 (1) , 31-44. https://doi.org/10.1006/abbi.1999.1138
    64. Ali Bu-Abbas, Michael N. Clifford, Ron Walker, Costas Ioannides. Modulation of hepatic cytochrome P450 activity and carcinogen bioactivation by black and decaffeinated black tea. Environmental Toxicology and Pharmacology 1999, 7 (1) , 41-47. https://doi.org/10.1016/S1382-6689(98)00049-0
    65. Alf H. Haukenes, Christine M. Moffitt. Concentrations of Erythromycin in Maturing Chinook Salmon after Intraperitoneal Injection of One of Two Drug Formulations. Journal of Aquatic Animal Health 1999, 11 (1) , 61-67. https://doi.org/10.1577/1548-8667(1999)011<0061:COEIMC>2.0.CO;2
    66. P.E.B Reilly, S.R Mason, M.A Read. Human, rat and crocodile liver microsomal monooxygenase activities measured using diazepam and nifedipine: effects of CYP3A inhibitors and relationship to immunochemically detected CYP3A apoprotein. Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology 1999, 122 (2) , 197-204. https://doi.org/10.1016/S0742-8413(98)10106-8
    67. J. C. Gorski, D. R. Jones, M. A. Hamman, S. A. Wrighton, S. D. Hall. Biotransformation of alprazolam by members of the human cytochrome P4503A subfamily. Xenobiotica 1999, 29 (9) , 931-944. https://doi.org/10.1080/004982599238173
    68. Brian G. Lake, Anthony B. Renwick, Morag E. Cunninghame, Roger J. Price, Dominic Surry, David C. Evans. Comparison of the effects of some CYP3A and other enzyme inducers on replicative DNA synthesis and cytochrome P450 isoforms in rat liver. Toxicology 1998, 131 (1) , 9-20. https://doi.org/10.1016/S0300-483X(98)00085-7
    69. Matt J Cheesman, Paul E.B Reilly. Differential inducibility of specific mRNA corresponding to five CYP3A isoforms in female rat liver by RU486 and food deprivation. Biochemical Pharmacology 1998, 56 (4) , 473-481. https://doi.org/10.1016/S0006-2952(98)00163-4
    70. Janice M. Huss, Charles B. Kasper. Nuclear Receptor Involvement in the Regulation of Rat Cytochrome P450 3A23 Expression. Journal of Biological Chemistry 1998, 273 (26) , 16155-16162. https://doi.org/10.1074/jbc.273.26.16155
    71. Amaia Irizar, Costas Ioannides. Marked inhibition of hepatic cytochrome P450 activity in cholesterol-induced atherosclerosis in rabbits. Toxicology 1998, 126 (3) , 179-193. https://doi.org/10.1016/S0300-483X(98)00009-2
    72. K. E. Thummel, G. R. Wilkinson. IN VITRO AND IN VIVO DRUG INTERACTIONS INVOLVING HUMAN CYP3A. Annual Review of Pharmacology and Toxicology 1998, 38 (1) , 389-430. https://doi.org/10.1146/annurev.pharmtox.38.1.389
    73. G. SMITH, M. J. STUBBINS, L. W. HARRIES, C. R. WOLF. Molecular genetics of the human cytochrome P450 monooxygenase superfamily. Xenobiotica 1998, 28 (12) , 1129-1165. https://doi.org/10.1080/004982598238868
    74. TERESA M. PEREIRA, JAN CARLSTEDT-DUKE, M. CELESTE LECHNER, JAN-ÅKE GUSTAFSSON. Identification of a Functional Glucocorticoid Response Element in the CYP3A1/IGC2 Gene. DNA and Cell Biology 1998, 17 (1) , 39-49. https://doi.org/10.1089/dna.1998.17.39
    75. Kim J. Rich, Alan R. Boobis. Expression and inducibility of P450 enzymes during liver ontogeny. Microscopy Research and Technique 1997, 39 (5) , 424-435. https://doi.org/10.1002/(SICI)1097-0029(19971201)39:5<424::AID-JEMT5>3.0.CO;2-G
    76. Randall S. Taylor, Steven M. Jones, Rolf H. Dahl, Mark H. Nordeen, Kathryn E. Howell. Characterization of the Golgi Complex Cleared of Proteins in Transit and Examination of Calcium Uptake Activities. Molecular Biology of the Cell 1997, 8 (10) , 1911-1931. https://doi.org/10.1091/mbc.8.10.1911
    77. M Hebert. Contributions of hepatic and intestinal metabolism and P-glycoprotein to cyclosporine and tacrolimus oral drug delivery. Advanced Drug Delivery Reviews 1997, 27 (2-3) , 201-214. https://doi.org/10.1016/S0169-409X(97)00043-4
    78. Buxiang Sun, Morio Fukuhara. Effects of co-administration of butylated hydroxytoluene, butylated hydroxyanisole and flavonoids on the activation of mutagens and drug-metabolizing enzymes in mice. Toxicology 1997, 122 (1-2) , 61-72. https://doi.org/10.1016/S0300-483X(97)00078-4
    79. E. Sampol, A. Mirrione, P.H. Villard, P. Piccerelle, H. Scoma, P. Berbis, Y. Barra, A. Durand, B. Lacarelle. Evidence for a Tissue-Specific Induction of Cutaneous CYP2E1 by Dexamethasone. Biochemical and Biophysical Research Communications 1997, 235 (3) , 557-561. https://doi.org/10.1006/bbrc.1997.6829
    80. Hindupur K Anandatheerthavarada, Sankar Addya, Radhey S Dwivedi, Gopa Biswas, Jayati Mullick, Narayan G Avadhani. Localization of Multiple Forms of Inducible Cytochromes P450 in Rat Liver Mitochondria: Immunological Characteristics and Patterns of Xenobiotic Substrate Metabolism. Archives of Biochemistry and Biophysics 1997, 339 (1) , 136-150. https://doi.org/10.1006/abbi.1996.9855
    81. Nobumitsu Hanioka, Hideto Jinno, Tetsuji Nishimura, Masanori Ando. Effect of 2,4,4′-trichloro-2′-hydroxydiphenyl ether on cytochrome P450 enzymes in the rat liver. Chemosphere 1997, 34 (4) , 719-730. https://doi.org/10.1016/S0045-6535(97)00464-5
    82. Angeliki P. Kourounakis, Eleni A. Rekka, Panos N. Kourounakis. Effect of Guaiazulene on Some Cytochrome P450 Activities. Implication in the Metabolic Activation and Hepatotoxicity of Paracetamol. Archiv der Pharmazie 1997, 330 (1-2) , 7-11. https://doi.org/10.1002/ardp.19973300103
    83. L. Tantcheva, T. Stoytchev, D. Rangelova. Influence of hydrocortisone on the analgesic effect, toxicity and metabolism of aspirin in mice. General Pharmacology: The Vascular System 1997, 28 (1) , 123-128. https://doi.org/10.1016/S0306-3623(96)00080-8
    84. Veena Puri, Krishan K. Kohli. Purification and Characterization of Dexamethasone Inducible Hepatic Cytochrome P450 Isozymes from Rhesus Monkey. Drug and Chemical Toxicology 1997, 20 (1-2) , 11-19. https://doi.org/10.3109/01480549709011075
    85. M.R. Martinez-Larrañaga, A. Anadón, M.J. Diaz, R. Fernandez, B. Sevil, M.L. Fernandez-Cruz, M.C. Fernandez, M.A. Martinez, R. Anton. Induction of cytochrome P4501 A1 and P4504A1 activities andperoxisomal proliferation by furnonisin B1. Toxicology and Applied Pharmacology 1996, 141 (1) , 185-194. https://doi.org/10.1016/S0041-008X(96)80024-X
    86. Lars W. Wormhoudt, Jan H.T.M. Ploemen, Isabelle de Waziers, Jan N.M. Commandeur, Philippe H. Beaune, Peter J. van Bladeren, Nico P.E. Vermeulen. Inter-individual variability in the oxidation of 1,2-dibromoethane: use of heterologously expressed human cytochrome P450 and human liver microsomes. Chemico-Biological Interactions 1996, 101 (3) , 175-192. https://doi.org/10.1016/0009-2797(96)03723-4
    87. Shizuo Narimatsu, Masayuki Mochida, Takahiro Matsumoto, Yasuhiro Masubuchi, Toshiharu Horie, Kiyoshi Nagata, Yoshihiko Funae, Arthur K. Cho, Tokuji Suzuki. Cytochrome P450 enzymes involved in the enhancement of propranolol N-desisopropylation after repeated administration of propranolol in rats. Chemico-Biological Interactions 1996, 101 (3) , 207-224. https://doi.org/10.1016/0009-2797(96)03726-X
    88. K KATO. Developmental expression of cytochrome p450s within intrasplenically transplanted fetal hepatocytes. Cell Transplantation 1996, 5 (5) , S27-S30. https://doi.org/10.1016/0963-6897(96)00035-8
    89. J P McNamee, S M Kobus, G S Marks. The apoprotein of cytochrome P450 3A2 does not selectively direct alkylation to one of four pyrrole rings of N -vinylprotoporphyrin IX. Canadian Journal of Physiology and Pharmacology 1996, 74 (8) , 996-1000. https://doi.org/10.1139/y96-131
    90. M Lekehal, D Pessayre, J M Lereau, C Moulis, I Fourasté, D Fau. Hepatotoxicity of the herbal medicine germander: Metabolic activation of its furano diterpenoids by cytochrome P450 3A Depletes cytoskeleton-associated protein thiols and forms plasma membrane blebs in rat hepatocytes. Hepatology 1996, 24 (1) , 212-218. https://doi.org/10.1002/hep.510240134
    91. B. Sun, M. Fukuhara, T. Kinoshita, M. Kimura, F. Ushio. Differential induction of isozymes of drug-metabolizing enzymes by butylated hydroxytoluene in mice and Chinese hamsters. Food and Chemical Toxicology 1996, 34 (7) , 595-601. https://doi.org/10.1016/0278-6915(96)00020-8
    92. M.J. Cheesman, S.R. Mason, P.E.B. Reilly. Effects of food deprivation and adrenalectomy on CYP3A induction by RU486 in female rats. The Journal of Steroid Biochemistry and Molecular Biology 1996, 58 (4) , 447-454. https://doi.org/10.1016/0960-0760(96)00063-5
    93. Robert Martini, Michael Murray. Characterization of the in vivo inhibition of rat hepatic microsomal aldehyde dehydrogenase activity by metyrapone. Biochemical Pharmacology 1996, 51 (9) , 1187-1193. https://doi.org/10.1016/0006-2952(96)00054-8
    94. Joanne Zurlo, Linda M. Arterburn. Characterization of a primary hepatocyte culture system for toxicological studies. In Vitro Cellular & Developmental Biology - Animal 1996, 32 (4) , 211-220. https://doi.org/10.1007/BF02722948
    95. Alexandros N. Alexidis, Jan N.M. Commandeur, Eleni A. Rekka, Ed Groot, Panos N. Kourounakis, Nico P.E. Vermeulen. Novel piperidine derivatives: inhibitory properties towards cytochrome P450 isoforms, and cytoprotective and cytotoxic characteristics. Environmental Toxicology and Pharmacology 1996, 1 (1) , 81-88. https://doi.org/10.1016/1382-6689(95)00012-7
    96. Maria Carelli, Maria Cabello Porras, Milena Rizzardini, Lavinia Cantoni. Modulation of constitutive and inducible hepatic cytochrome(s) P-450 by interferon β in mice. Journal of Hepatology 1996, 24 (2) , 230-237. https://doi.org/10.1016/S0168-8278(96)80034-1
    97. David Kupfer. The Covalent Binding of Tamoxifen to Proteins and DNA. 1996, 201-230. https://doi.org/10.1007/978-1-4612-4092-1_9
    98. David Kupfer, Shangara S. Dehal. [17] Tamoxifen metabolism by microsomal cytochrome P450 and flavin-containing monooxygenase. 1996, 152-163. https://doi.org/10.1016/S0076-6879(96)72019-0
    99. R F Witkamp, S M Nijmeijer, A S van Miert. Cytochrome P-450 complex formation in rat liver by the antibiotic tiamulin. Antimicrobial Agents and Chemotherapy 1996, 40 (1) , 50-54. https://doi.org/10.1128/AAC.40.1.50
    100. Kazuya Kato, W. John B. Hodgson, Nader G. Abraham, Kazhuiko Onodera, Masato Imai, Shinichi Kasai, Michio Mito. Expression and Inducibility of Cytochrome P450 Iiia Family within Intrasplenically Transplanted Fetal Hepatocytes. Cell Transplantation 1996, 5 (1) , 117-122. https://doi.org/10.1177/096368979600500116
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