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Preparation and properties of porcine relaxin derivatives shortened at the amino terminus of the A-chain

Cite this: Biochemistry 1986, 25, 20, 5998–6004
Publication Date (Print):October 7, 1986
https://doi.org/10.1021/bi00368a025
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    Cited By

    This article is cited by 18 publications.

    1. Julio A. Camarero and, Tom W. Muir. Biosynthesis of a Head-to-Tail Cyclized Protein with Improved Biological Activity. Journal of the American Chemical Society 1999, 121 (23) , 5597-5598. https://doi.org/10.1021/ja990929n
    2. Virginia W. Cornish,, Klaus M. Hahn, and, Peter G. Schultz. Site-Specific Protein Modification Using a Ketone Handle. Journal of the American Chemical Society 1996, 118 (34) , 8150-8151. https://doi.org/10.1021/ja961216x
    3. Ross A.D. Bathgate, Martina Kocan, Daniel J. Scott, M. Akhter Hossain, Sara V. Good, Sergey Yegorov, Jan Bogerd, Paul R. Gooley. The relaxin receptor as a therapeutic target – perspectives from evolution and drug targeting. Pharmacology & Therapeutics 2018, 187 , 114-132. https://doi.org/10.1016/j.pharmthera.2018.02.008
    4. Nitin A Patil, K Johan Rosengren, Frances Separovic, John D Wade, Ross A D Bathgate, Mohammed Akhter Hossain. Relaxin family peptides: structure–activity relationship studies. British Journal of Pharmacology 2017, 174 (10) , 950-961. https://doi.org/10.1111/bph.13684
    5. Mohammed Akhter Hossain, K. Johan Rosengren, Chrishan S. Samuel, Fazel Shabanpoor, Linda J. Chan, Ross A.D. Bathgate, John D. Wade. The Minimal Active Structure of Human Relaxin-2. Journal of Biological Chemistry 2011, 286 (43) , 37555-37565. https://doi.org/10.1074/jbc.M111.282194
    6. Jae-Il Park, Jenia Semyonov, Wei Yi, Chia Lin Chang, Sheau Yu Teddy Hsu. Regulation of Receptor Signaling by Relaxin A Chain Motifs. Journal of Biological Chemistry 2008, 283 (46) , 32099-32109. https://doi.org/10.1074/jbc.M806817200
    7. Mohammed Akhter Hossain, K. Johan Rosengren, Linda M. Haugaard-Jönsson, Soude Zhang, Sharon Layfield, Tania Ferraro, Norelle L. Daly, Geoffrey W. Tregear, John D. Wade, Ross A.D. Bathgate. The A-chain of Human Relaxin Family Peptides Has Distinct Roles in the Binding and Activation of the Different Relaxin Family Peptide Receptors. Journal of Biological Chemistry 2008, 283 (25) , 17287-17297. https://doi.org/10.1074/jbc.M801911200
    8. Ross A. Bathgate, Richard Ivell, Barbara M. Sanborn, O. David Sherwood, Roger J. Summers. International Union of Pharmacology LVII: Recommendations for the Nomenclature of Receptors for Relaxin Family Peptides. Pharmacological Reviews 2006, 58 (1) , 7-31. https://doi.org/10.1124/pr.58.1.9
    9. Lily S. Tashima, Sandra Y. Yamamoto, Maaya Yasuda, Lynnae K. Millar, Gillian D. Bryant-Greenwood. Decidual relaxins: Gene and protein up-regulation in preterm premature rupture of the membranes by complementary DNA arrays and quantitative immunocytochemistry. American Journal of Obstetrics and Gynecology 2002, 187 (3) , 785-797. https://doi.org/10.1067/mob.2002.125763
    10. Wolfgang König. Peptide and Protein Hormones. 2000https://doi.org/10.1002/14356007.a19_061
    11. Christian Schwabe, Erika E. Büllesbach. Retro-D-Relaxin. 1998, 129-132. https://doi.org/10.1007/978-3-662-12909-8_15
    12. Christian Schwabe, Erika E. Büllesbach. The N-Terminal Region of the Relaxin A Chain. 1998, 49-57. https://doi.org/10.1007/978-3-662-12909-8_7
    13. Christian Schwabe. Theoretical limitations of molecular phylogenetics and the evolution of relaxins. Comparative Biochemistry and Physiology Part B: Comparative Biochemistry 1994, 107 (2) , 167-177. https://doi.org/10.1016/0305-0491(94)90036-1
    14. G. Kesava Reddy, Sripad Gunwar, Carla B. Green, David T.W. Fei, Anthony B. Chen, Simon C.M. Kwok. Purification and characterization of recombinant porcine prorelaxin expressed in Escherichia coli. Archives of Biochemistry and Biophysics 1992, 294 (2) , 579-585. https://doi.org/10.1016/0003-9861(92)90728-F
    15. Christian Schwabe, Erika E. Büllesbach. Relaxin. Comparative Biochemistry and Physiology Part B: Comparative Biochemistry 1990, 96 (1) , 15-21. https://doi.org/10.1016/0305-0491(90)90335-Q
    16. Edward H. Frieden, H.Gail Pollock, Bernard G. Steinetz, Allen B. Rawitch. Structure of a porcine relaxin inactive on the mouse pubic ligament. Archives of Biochemistry and Biophysics 1988, 266 (2) , 334-342. https://doi.org/10.1016/0003-9861(88)90265-2
    17. E.E. BÜLLESBACH, C. SCHWABE. On the receptor binding site of relaxins. International Journal of Peptide and Protein Research 1988, 32 (5) , 361-367. https://doi.org/10.1111/j.1399-3011.1988.tb01271.x
    18. E E Büllesbach, C Schwabe. Relaxin structure. Quasi allosteric effect of the NH2-terminal A-chain helix.. Journal of Biological Chemistry 1987, 262 (26) , 12496-12501. https://doi.org/10.1016/S0021-9258(18)45233-7

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