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Solid-Phase Peptide Synthesis. III. An Improved Synthesis of Bradykinin*

Cite this: Biochemistry 1964, 3, 9, 1385–1390
Publication Date (Print):September 1, 1964
https://doi.org/10.1021/bi00897a032
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    19. Justin M. Kollman, Leela Pandi, Michael R. Sawaya, Marcia Riley and Russell F. Doolittle . Crystal Structure of Human Fibrinogen. Biochemistry 2009, 48 (18) , 3877-3886. https://doi.org/10.1021/bi802205g
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    56. John W.B. Hershey, Nahum Sonenberg, Michael B. Mathews. Principles of Translational Control. Cold Spring Harbor Perspectives in Biology 2019, 11 (9) , a032607. https://doi.org/10.1101/cshperspect.a032607
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    63. Greg A. Slough. Solid-Phase Synthesis of Heterocycles in Practice. 2017, 1-22. https://doi.org/10.1007/7081_2016_3
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    66. Olga Avrutina. Synthetic Cystine-Knot Miniproteins – Valuable Scaffolds for Polypeptide Engineering. 2016, 121-144. https://doi.org/10.1007/978-3-319-32805-8_7
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    72. Olga Avrutina. Synthetic Cystine-Knot Miniproteins – Valuable Scaffolds for Polypeptide Engineering. 2015, 121-144. https://doi.org/10.1007/978-3-319-22473-2_7
    73. Rico Petersen, Jakob F. Jensen, Thomas E. Nielsen. An Improved Protocol for the Synthesis of 1-(Mesitylenesulfonyl)-3-nitro-1,2,4-triazole (MSNT). Organic Preparations and Procedures International 2014, 46 (3) , 267-271. https://doi.org/10.1080/00304948.2014.903145
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    75. Fa Liu, John P. Mayer. Protein Chemical Synthesis in Drug Discovery. 2014, 183-228. https://doi.org/10.1007/128_2014_598
    76. Xiaoyang Guan, Patrick K. Chaffey, Chen Zeng, Zhongping Tan. New Methods for Chemical Protein Synthesis. 2014, 155-192. https://doi.org/10.1007/128_2014_599
    77. Laurent Raibaut, Ouafâa El Mahdi, Oleg Melnyk. Solid Phase Protein Chemical Synthesis. 2014, 103-154. https://doi.org/10.1007/128_2014_609
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    80. Kleomenis Barlos, Knut Adermann. Strategy in Solid‐Phase Peptide Synthesis. 2010, 371-406. https://doi.org/10.1002/9783527631803.ch11
    81. Miroslav Soural, Jan Hlaváč, Viktor Krchňák. Linkers for Solid‐Phase Peptide Synthesis. 2010, 273-312. https://doi.org/10.1002/9783527631803.ch8
    82. . Merrifield Solid‐Phase Peptide Synthesis. 2010, 1905-1909. https://doi.org/10.1002/9780470638859.conrr428
    83. Nathan T. Ross, Brian R. McNaughton, Benjamin L. Miller. Combinatorial Chemistry in the Drug Discovery Process. 2010, 1-52. https://doi.org/10.1002/9780470571224.pse022
    84. Dipankar Das, Mavanur R. Suresh. Preclinical Development of Protein Pharmaceuticals: An overview. 2010, 1-28. https://doi.org/10.1002/9780470571224.pse088
    85. Michio Kurosu. Electrophile Cleavable Linker Units. 2009, 25-76. https://doi.org/10.1002/9780470749043.ch2
    86. Christian Bochet, Sébastien Mercier. Photolabile Linker Units. 2009, 151-193. https://doi.org/10.1002/9780470749043.ch5
    87. David C. Young, Anne Kasmar, Garrett Moraski, Tan-Yun Cheng, Andrew J. Walz, Jingdan Hu, Yanping Xu, Gregory W. Endres, Adam Uzieblo, Dirk Zajonc, Catherine E. Costello, Marvin J. Miller, D. Branch Moody. Synthesis of Dideoxymycobactin Antigens Presented by CD1a Reveals T Cell Fine Specificity for Natural Lipopeptide Structures. Journal of Biological Chemistry 2009, 284 (37) , 25087-25096. https://doi.org/10.1074/jbc.M109.000802
    88. Peter D. White. Acid‐Labile Resins. 2008, 381-416. https://doi.org/10.1002/9783527626175.ch14
    89. Soo Sung Kang, Mark A. Lipton. Photolabile and Miscellaneous Linkers/Resins. 2008, 467-492. https://doi.org/10.1002/9783527626175.ch17
    90. Sandra Claro, Maria Etsuko Miyamoto Oshiro, Edna Freymuller, Eduardo Katchburian, Esper George Kallas, Paulo Sérgio Cerri, Alice Teixeira Ferreira. γ-Radiation induces apoptosis via sarcoplasmatic reticulum in guinea pig ileum smooth muscle cells. European Journal of Pharmacology 2008, 590 (1-3) , 20-28. https://doi.org/10.1016/j.ejphar.2008.05.038
    91. Rolf Breinbauer. Solid‐Phase Synthesis of Biomolecules. 2008, 1-9. https://doi.org/10.1002/9780470048672.wecb552
    92. Zhihua Liu, Victor J. Hruby. Naturally Occurring Peptide Hormones and Neurotransmitters: Synthesis. 2008, 1-32. https://doi.org/10.1002/9780470048672.wecb658
    93. John M. Stewart. Remembering Bruce: The early years. Peptide Science 2008, 90 (3) , 185-187. https://doi.org/10.1002/bip.20861
    94. Arnold Marglin. Insulin and solid‐phase synthesis, 1964–1970. Peptide Science 2008, 90 (3) , 200-202. https://doi.org/10.1002/bip.20912
    95. Alexander R. Mitchell. Bruce Merrifield and solid‐phase peptide synthesis: A historical assessment. Peptide Science 2008, 90 (3) , 175-184. https://doi.org/10.1002/bip.20925
    96. Jens Waschke, Carlos Menendez-Castro, Paola Bruggeman, Rainer Koob, Masayuki Amagai, Hermann J. Gruber, Detlev Drenckhahn, Werner Baumgartner. Imaging and Force Spectroscopy on Desmoglein 1 Using Atomic Force Microscopy Reveal Multivalent Ca2+-Dependent, Low-Affinity Trans-Interaction. Journal of Membrane Biology 2007, 216 (2-3) , 83-92. https://doi.org/10.1007/s00232-007-9037-9
    97. Ana Pena, Brigitte Murat, Miguel Trueba, Maria A. Ventura, Gyslaine Bertrand, Ling Ling Cheng, Stoytcho Stoev, Hazel H. Szeto, Nga Wo, Gabrielle Brossard, Claudine Serradeil-Le Gal, Maurice Manning, Gilles Guillon. Pharmacological and Physiological Characterization of d[Leu4, Lys8]Vasopressin, the First V1b-Selective Agonist for Rat Vasopressin/Oxytocin Receptors. Endocrinology 2007, 148 (9) , 4136-4146. https://doi.org/10.1210/en.2006-1633
    98. John M. Stewart. Bradykinin in Solid-phase Peptide Synthesis. International Journal of Peptide Research and Therapeutics 2007, 13 (1-2) , 3-5. https://doi.org/10.1007/s10989-006-9043-2
    99. Maurice Manning, Stoytcho Stoev, Ling Ling Cheng, Nga Wo, W. Y. Chan, Hazel H. Szeto. The Role of the Merrifield Solid Phase Method in the Discovery and Exploration of a New Class of Selective Vasopressin Hypotensive Agonists. International Journal of Peptide Research and Therapeutics 2007, 13 (1-2) , 7-17. https://doi.org/10.1007/s10989-007-9089-9
    100. A-L Nouvion, J Thibaut, O D Lohez, S Venet, P Colas, G Gillet, P Lalle. Modulation of Nr-13 antideath activity by peptide aptamers. Oncogene 2007, 26 (5) , 701-710. https://doi.org/10.1038/sj.onc.1209832
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