Emulsion-Based Synthesis of Reversibly Swellable, Magnetic Nanoparticle-Embedded Polymer MicrocapsulesClick to copy article linkArticle link copied!
Abstract
A one-step, template-free synthetic method for preparing polymeric microcapsules with iron oxide (γ-Fe2O3) magnetic nanoparticles (MPs) embedded in the polymer shell is reported. Using a simple emulsification of the multiphase mixture containing liquid prepolymer and MPs in chloroform solution, double emulsions comprising a chloroform core and MPs/polymer shell were spontaneously formed. After exposure to UV light, these double emulsions converted to microcapsules with a polymerized composite shell. The evolution from the double emulsions to the microcapsules was examined by confocal laser scanning microscopy. One unusual feature of these microcapsules is the ability to change shape reversibly by osmotic swelling of the water core upon repetitive drying and hydration. The microcapsules had an intrinsic superparamagnetic response due to the presence of the magnetic nanoparticles and could be moved and collected by external magnetic fields.
†
Gwangju Institute of Science and Technology.
‡
North Carolina State University.
*
To whom correspondence should be addressed. E-mail: kimdy@ gist.ac.kr (D.Y.K.); [email protected] (O.D.V.).
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- Pengyao Xu, Kaijie Li, Hongbo Yu, Martien A. Cohen Stuart, Junyou Wang, Shenghu Zhou. One-Pot Syntheses of Porous Hollow Silica Nanoreactors Encapsulating Rare Earth Oxide Nanoparticles for Methylene Blue Degradation. Industrial & Engineering Chemistry Research 2019, 58
(9)
, 3726-3734. https://doi.org/10.1021/acs.iecr.9b00735
- Makoto Takafuji, Nanami Hano, Md. A. Alam, and Hirotaka Ihara . Fabrication of Hollow Silica Microspheres with Orderly Hemispherical Protrusions and Capability for Heat-Induced Controlled Cracking. Langmuir 2017, 33
(40)
, 10679-10689. https://doi.org/10.1021/acs.langmuir.7b02223
- Denis V. Voronin, Olga A. Sindeeva, Maxim A. Kurochkin, Oksana Mayorova, Ivan V. Fedosov, Oksana Semyachkina-Glushkovskaya, Dmitry A. Gorin, Valery V. Tuchin, and Gleb B. Sukhorukov . In Vitro and in Vivo Visualization and Trapping of Fluorescent Magnetic Microcapsules in a Bloodstream. ACS Applied Materials & Interfaces 2017, 9
(8)
, 6885-6893. https://doi.org/10.1021/acsami.6b15811
- Xiaojing Wang, Ji Feng, Yaocai Bai, Qiao Zhang, and Yadong Yin . Synthesis, Properties, and Applications of Hollow Micro-/Nanostructures. Chemical Reviews 2016, 116
(18)
, 10983-11060. https://doi.org/10.1021/acs.chemrev.5b00731
- Shuaishuai Liang, Jiang Li, Jia Man, and Haosheng Chen . Mass-Transfer-Induced Multistep Phase Separation in Emulsion Droplets: Toward Self-Assembly Multilayered Emulsions and Onionlike Microspheres. Langmuir 2016, 32
(31)
, 7882-7887. https://doi.org/10.1021/acs.langmuir.6b01665
- Jonathan S. Sander, Mathias Steinacher, Eve Loiseau, Ahmet F. Demirörs, Michele Zanini, Lucio Isa, and André R. Studart . Robust Microcompartments with Hydrophobically Gated Shells. Langmuir 2015, 31
(25)
, 6965-6970. https://doi.org/10.1021/acs.langmuir.5b00732
- Mohammed Ali, Sangita Bora, and Sujit Kumar Ghosh . Composite-Walled Magnetic Microcapsules at the Water–Toluene Interface by Ligand Polymerization. Langmuir 2014, 30
(34)
, 10449-10455. https://doi.org/10.1021/la5018054
- Hee-Jae Yoon, Tae Geuk Lim, Joo-Ho Kim, Young Min Cho, Yong Seok Kim, Ui Seok Chung, Jung Hyun Kim, Byoung Wook Choi, Won-Gun Koh, and Woo-Dong Jang . Fabrication of Multifunctional Layer-by-Layer Nanocapsules toward the Design of Theragnostic Nanoplatform. Biomacromolecules 2014, 15
(4)
, 1382-1389. https://doi.org/10.1021/bm401928f
- Elena Blanco, Stephanie Lam, Stoyan K. Smoukov, Krassimir P. Velikov, Saad A. Khan, and Orlin D. Velev . Stability and Viscoelasticity of Magneto-Pickering Foams. Langmuir 2013, 29
(32)
, 10019-10027. https://doi.org/10.1021/la4014224
- James J. O’Mahony, Mark Platt, Devrim Kilinc, and Gil Lee . Synthesis of Superparamagnetic Particles with Tunable Morphologies: The Role of Nanoparticle–Nanoparticle Interactions. Langmuir 2013, 29
(8)
, 2546-2553. https://doi.org/10.1021/la3047565
- Hassan Masoud and Alexander Alexeev . Controlled Release of Nanoparticles and Macromolecules from Responsive Microgel Capsules. ACS Nano 2012, 6
(1)
, 212-219. https://doi.org/10.1021/nn2043143
- Bin Xu, Hongjing Dou, Ke Tao, Kang Sun, Jing Ding, Weibin Shi, Xiasheng Guo, Jiyu Li, Dong Zhang, and Kun Sun . “Two-in-One” Fabrication of Fe3O4/MePEG-PLA Composite Nanocapsules as a Potential Ultrasonic/MRI Dual Contrast Agent. Langmuir 2011, 27
(19)
, 12134-12142. https://doi.org/10.1021/la202096x
- Aaron P. Esser-Kahn, Susan A. Odom, Nancy R. Sottos, Scott R. White, and Jeffrey S. Moore . Triggered Release from Polymer Capsules. Macromolecules 2011, 44
(14)
, 5539-5553. https://doi.org/10.1021/ma201014n
- Jiwei Liu, Yu Zhang, Chunyu Wang, Ruizhi Xu, Zhongping Chen and Ning Gu . Magnetically Sensitive Alginate-Templated Polyelectrolyte Multilayer Microcapsules for Controlled Release of Doxorubicin. The Journal of Physical Chemistry C 2010, 114
(17)
, 7673-7679. https://doi.org/10.1021/jp911933b
- Marta Horecha, Volodymyr Senkovskyy, Manfred Stamm and Anton Kiriy. One-Pot Synthesis of Thermoresponsive PNIPAM Hydrogel Microcapsules Designed to Function in Apolar Media. Macromolecules 2009, 42
(15)
, 5811-5817. https://doi.org/10.1021/ma9008934
- Qing Zhang, Alideertu Dong, Yongai Zhai, Fengqi Liu and Ge Gao. Synthesis of 1,4-Bis(o-cyanostyryl)benzene−Silica Nanoparticles with Core−Shell Structures and Effects of Reaction Conditions. The Journal of Physical Chemistry C 2009, 113
(28)
, 12033-12039. https://doi.org/10.1021/jp902472m
- Brian P. Mason, Steven M. Hira, Geoffrey F. Strouse and D. Tyler McQuade. Microcapsules with Three Orthogonal Reactive Sites. Organic Letters 2009, 11
(7)
, 1479-1482. https://doi.org/10.1021/ol802843v
- Claudia Feldgitscher, Herwig Peterlik, Michael Puchberger and Guido Kickelbick . Structural Investigations on Hybrid Polymers Suitable as a Nanoparticle Precipitation Environment. Chemistry of Materials 2009, 21
(4)
, 695-705. https://doi.org/10.1021/cm802171s
- Bridgette M. Budhlall, Manuel Marquez and Orlin D. Velev . Microwave, Photo- and Thermally Responsive PNIPAm−Gold Nanoparticle Microgels. Langmuir 2008, 24
(20)
, 11959-11966. https://doi.org/10.1021/la8019556
- Song Yang, Huarong Liu and Zhicheng Zhang. Fabrication of Novel Multihollow Superparamagnetic Magnetite/Polystyrene Nanocomposite Microspheres via Water-in-Oil-in-Water Double Emulsions. Langmuir 2008, 24
(18)
, 10395-10401. https://doi.org/10.1021/la800657k
- Liqin Ge, Keiji Nagai, ZhongZe Gu, Yoshinori Shimada, Hiroaki Nishimura, Noriaki Miyanaga, Yasukazu Izawa, Kunioki Mima and Takayoshi Norimatsu . Dry Tin Dioxide Hollow Microshells and Extreme Ultraviolet Radiation Induced by CO2 Laser Illumination. Langmuir 2008, 24
(18)
, 10402-10406. https://doi.org/10.1021/la800766q
- Ru Qiao,, Xiao Li Zhang,, Ri Qiu,, Yan Li, and, Young Soo Kang. Fabrication of Superparamagnetic Cobalt Nanoparticles-Embedded Block Copolymer Microcapsules. The Journal of Physical Chemistry C 2007, 111
(6)
, 2426-2429. https://doi.org/10.1021/jp067534s
- David B. Lawrence,, Tong Cai,, Zhibing Hu,, Manuel Marquez, and, A. D. Dinsmore. Temperature-Responsive Semipermeable Capsules Composed of Colloidal Microgel Spheres. Langmuir 2007, 23
(2)
, 395-398. https://doi.org/10.1021/la062676z
- Yunwei Niu, Xiyuan Zhang, Yanxiang Kang, Pingli Sun, Huiqin Liu, Zuobing Xiao, Di Zhao. Magnetic microcapsules based on Fe3O4 nanoparticles: Preparation, properties, and applications. Materials Today Communications 2024, 39 , 108660. https://doi.org/10.1016/j.mtcomm.2024.108660
- Jiaxing Zhang, Wenlong Chen, Rui Zhai, Hui Chen, Zhihua Shan. Application of noise reduction and heat insulation based on controlled-size polystyrene hollow microspheres. Journal of Industrial and Engineering Chemistry 2022, 115 , 476-490. https://doi.org/10.1016/j.jiec.2022.08.034
- Roman Verkhovskii, Alexey Ermakov, Oleg Grishin, Mikhail A. Makarkin, Ilya Kozhevnikov, Mikhail Makhortov, Anastasiia Kozlova, Samia Salem, Valery Tuchin, Daniil Bratashov. The Influence of Magnetic Composite Capsule Structure and Size on Their Trapping Efficiency in the Flow. Molecules 2022, 27
(18)
, 6073. https://doi.org/10.3390/molecules27186073
- Beatriz Fresco-Cala, Soledad Cárdenas. Advanced polymeric solids containing nano- and micro-particles prepared via emulsion-based polymerization approaches. A review. Analytica Chimica Acta 2022, 1208 , 339669. https://doi.org/10.1016/j.aca.2022.339669
- Marcus U. Witt, Joachim Landers, Stephan Hinrichs, Soma Salamon, Juri Kopp, Birgit Hankiewicz, Heiko Wende, Regine von Klitzing. Magnetic response of CoFe
2
O
4
nanoparticles confined in a PNIPAM microgel network. Soft Matter 2022, 18
(5)
, 1089-1099. https://doi.org/10.1039/D1SM01597D
- Graciane Resende, Gabriel V. S. Dutra, Maria S. B. Neta, Olacir A. Araújo, Sacha B. Chaves, Fabricio Machado. Well Defined Poly(Methyl Methacrylate)-Fe3O4/Poly(Vinyl Pivalate) Core–Shell Superparamagnetic Nanoparticles: Design and Evaluation of In Vitro Cytotoxicity Activity Against Cancer Cells. Polymers 2020, 12
(12)
, 2868. https://doi.org/10.3390/polym12122868
- Tengyu He, Jesse V. Jokerst. Structured micro/nano materials synthesized
via
electrospray: a review. Biomaterials Science 2020, 8
(20)
, 5555-5573. https://doi.org/10.1039/D0BM01313G
- Mohammed Ali, Sujit Kumar Ghosh. Liquid-liquid interface as scaffold for self-assembly of nanostructures into functional materials. 2020, 515-536. https://doi.org/10.1016/B978-0-12-816770-0.00031-9
- Mallinath S. Birajdar, Jonghwi Lee. Hierarchically structured microgels of SPIONs, nanofibers, and alginate for copper ion removal. Journal of Industrial and Engineering Chemistry 2019, 77 , 303-308. https://doi.org/10.1016/j.jiec.2019.04.052
- Wishulada Injumpa, Tanatorn Khotavivattana, Numpon Insin. Synthesis of peroxy-functionalized magnetic mesoporous silica for epoxidation of vinyl acetate. Journal of Magnetism and Magnetic Materials 2019, 475 , 579-585. https://doi.org/10.1016/j.jmmm.2018.11.111
- Olga A. Inozemtseva, Sergey V. German, Nikita A. Navolokin, Alla B. Bucharskaya, Galina N. Maslyakova, Dmitry A. Gorin. Encapsulated Magnetite Nanoparticles. 2018, 175-192. https://doi.org/10.1016/B978-0-12-813855-7.00006-4
- . Shear‐Induced Generation of Controllable Multiple Emulsions in Microfluidic Devices. 2017, 11-34. https://doi.org/10.1002/9783527803637.ch2
- Devi Henam Sylvia, Singh Henam Premananda, Singh Thiyam David. Green synthesized urchin like Pt/Cu bimetallic photonanocatalysts: Understanding composition effect. Materials Research Bulletin 2017, 86 , 277-286. https://doi.org/10.1016/j.materresbull.2016.10.030
- Rimesh Augustine, Johnson V. John, Il Kim. Nanoparticle-Homing Polymers as Platforms for Theranostic Applications. 2017, 203-222. https://doi.org/10.1016/B978-0-12-809717-5.00007-5
- Tao Wang, Ren Wang, Zhengxing Chen, Qixin Zhong. Magnetization of eugenol to fabricate magnetic-responsive emulsions for targeted delivery of caffeic acid phenethyl ester. RSC Advances 2017, 7
(69)
, 43455-43463. https://doi.org/10.1039/C7RA08167G
- Alexander S. Timin, Hui Gao, Denis V. Voronin, Dmitry A. Gorin, Gleb B. Sukhorukov. Inorganic/Organic Multilayer Capsule Composition for Improved Functionality and External Triggering. Advanced Materials Interfaces 2017, 4
(1)
https://doi.org/10.1002/admi.201600338
- Jinde Zhang, Huarong Liu. A novel approach to preparing polystyrene/Fe3O4 multihollow microspheres with porous walls. Colloid and Polymer Science 2016, 294
(11)
, 1755-1763. https://doi.org/10.1007/s00396-016-3938-z
- Luis A. Puentes-Vara, Karla M. Gregorio-Jauregui, Ana M. Bolarín, Ma. E. Navarro-Clemente, Héctor J. Dorantes, Mónica Corea. Effects of surfactant and polymerization method on the synthesis of magnetic colloidal polymeric nanoparticles. Journal of Nanoparticle Research 2016, 18
(7)
https://doi.org/10.1007/s11051-016-3524-9
- Dipali R. Bagal‐Kestwal, Rakesh M. Kestwal, Been H. Chiang. Bio‐based Nanomaterials and Their Bionanocomposites. 2016, 255-330. https://doi.org/10.1002/9783527683772.ch8
- P. M. Visakh. Introduction for Nanomaterials and Nanocomposites: State of Art, New Challenges, and Opportunities. 2016, 1-20. https://doi.org/10.1002/9783527683772.ch1
- Iris Tavernier, Wahyu Wijaya, Paul Van der Meeren, Koen Dewettinck, Ashok R. Patel. Food-grade particles for emulsion stabilization. Trends in Food Science & Technology 2016, 50 , 159-174. https://doi.org/10.1016/j.tifs.2016.01.023
- Samuel Levi, Valérie Mancier, Céline Rousse, Omar Lozano Garcia, Jorge Mejia, Maribel Guzman, Stéphane Lucas, Patrick Fricoteaux. Synthesis of spherical copper-platinum nanoparticles by sonoelectrochemistry followed by conversion reaction. Electrochimica Acta 2015, 176 , 567-574. https://doi.org/10.1016/j.electacta.2015.06.155
- You-Jin Kim, Jonghwi Lee. Translational and rotational motion control of microgels enabling shoaling and schooling. Soft Matter 2015, 11
(5)
, 994-1000. https://doi.org/10.1039/C4SM02450H
- Jingxian Huang, Chongdai Luo, Wanbo Li, Yan Li, Yu Shrike Zhang, Jianhua Zhou, Qing Jiang. Eccentric magnetic microcapsules for orientation-specific and dual stimuli-responsive drug release. Journal of Materials Chemistry B 2015, 3
(22)
, 4530-4538. https://doi.org/10.1039/C5TB00263J
- Goran T. Vladisavljević, Bing Wang, Marijana M. Dragosavac, Richard G. Holdich. Production of food-grade multiple emulsions with high encapsulation yield using oscillating membrane emulsification. Colloids and Surfaces A: Physicochemical and Engineering Aspects 2014, 458 , 78-84. https://doi.org/10.1016/j.colsurfa.2014.05.011
- O. Shevchuk, V. Serdiuk, N. Bukartyk, R. Moncibovich, V. Tokarev. Microencapsulation of liquid and solid substances by reactive polymers. Journal of Microencapsulation 2014, 31
(4)
, 390-398. https://doi.org/10.3109/02652048.2013.863397
- QING ZHANG. SYNTHESIS OF
ZnS
:
Mn
/SILICA CORE/SHELL MICROSPHERES WITH A COMBINATION OF SOL–GEL AND SELF-TEMPLATING TECHNIQUES. Nano 2014, 09
(03)
, 1450028. https://doi.org/10.1142/S1793292014500283
- Boris I. Kharisov, H. V. Rasika Dias, Oxana V. Kharissova, Alejandro Vázquez, Yolanda Peña, Idalia Gómez. Solubilization, dispersion and stabilization of magnetic nanoparticles in water and non-aqueous solvents: recent trends. RSC Adv. 2014, 4
(85)
, 45354-45381. https://doi.org/10.1039/C4RA06902A
- Suk Fun Chin, Aressa Azman, Suh Cem Pang. Size Controlled Synthesis of Starch Nanoparticles by a Microemulsion Method. Journal of Nanomaterials 2014, 2014 , 1-7. https://doi.org/10.1155/2014/763736
- Xianglong Zhao, Guowen Meng, Fangming Han, Xiangdong Li, Bensong Chen, Qiaoling Xu, Xiaoguang Zhu, Zhaoqin Chu, Mingguang Kong, Qing Huang. Nanocontainers made of Various Materials with Tunable Shape and Size. Scientific Reports 2013, 3
(1)
https://doi.org/10.1038/srep02238
- Vellingiri Sreevani, Krishnamurthy Shanthi, Soundarapandian Kannan. Goat red blood cells as precursor for iron oxide nanocrystal synthesis to develop nuclear targeted lung cancer therapy. Materials Research Bulletin 2013, 48
(9)
, 3164-3171. https://doi.org/10.1016/j.materresbull.2013.04.079
- Robert Taylor, Sylvain Coulombe, Todd Otanicar, Patrick Phelan, Andrey Gunawan, Wei Lv, Gary Rosengarten, Ravi Prasher, Himanshu Tyagi. Small particles, big impacts: A review of the diverse applications of nanofluids. Journal of Applied Physics 2013, 113
(1)
https://doi.org/10.1063/1.4754271
- Bin Xu, Rong Lu, Hongjing Dou, Ke Tao, Kang Sun, Yuanyuan Qiu, Jing Ding, Dong Zhang, Jiyu Li, Weibin Shi, Kun Sun. Exploring the structure–property relationships of ultrasonic/MRI dual imaging magnetite/PLA microbubbles: magnetite@Cavity versus magnetite@Shell systems. Colloid and Polymer Science 2012, 290
(16)
, 1617-1626. https://doi.org/10.1007/s00396-012-2682-2
- Nam Seon Kim, Jong-Duk Kim. Core–shell polymerization for monodispersed hollow polymer spheres embedded with magnetic nanoparticles. Journal of Industrial and Engineering Chemistry 2012, 18
(5)
, 1721-1729. https://doi.org/10.1016/j.jiec.2012.03.012
- Mi Sun Lee, Eun Young Mok, Won Cheol Shin, Jong Dai Kim, Jin-Chul Kim. Poly(vinyl alcohol) hollow microcapsules prepared by emulsification, salting out, and photo cross-linking method. Korean Journal of Chemical Engineering 2012, 29
(8)
, 1108-1113. https://doi.org/10.1007/s11814-012-0020-5
- Yang Lu, Liang Dong, Le-Cheng Zhang, Yu-De Su, Shu-Hong Yu. Biogenic and biomimetic magnetic nanosized assemblies. Nano Today 2012, 7
(4)
, 297-315. https://doi.org/10.1016/j.nantod.2012.06.011
- Zengjiang Wei, Chaoyang Wang, Shengwen Zou, Hao Liu, Zhen Tong. Fe2O3 nanoparticles as particulate emulsifier: Preparation of magnetic and biocompatible PLGA microcapsules. Colloids and Surfaces A: Physicochemical and Engineering Aspects 2011, 392
(1)
, 116-123. https://doi.org/10.1016/j.colsurfa.2011.09.043
- Xiaobo Hu, Zhen Tong, L. Andrew Lyon. One‐Pot Synthesis of Microcapsules with Nanoscale Inclusions. Macromolecular Rapid Communications 2011, 32
(18)
, 1461-1466. https://doi.org/10.1002/marc.201100338
- Kaliyaperumal Viswanathan. Preparation and characterization of fluorescent silica coated magnetic hybrid nanoparticles. Colloids and Surfaces A: Physicochemical and Engineering Aspects 2011, 386
(1-3)
, 11-15. https://doi.org/10.1016/j.colsurfa.2011.06.017
- Guohe Hu, Demei Yu, Jing Zhang, Honglu Liang, Zhen Cao. Synthesis of micron-sized poly(styrene-co-divinylbenzene) hollow particles from seeded emulsions by using swelling solvents. Colloid Journal 2011, 73
(4)
, 557-564. https://doi.org/10.1134/S1061933X11040077
- M. Chamundeeswari, V. Senthil, M. Kanagavel, S.M. Chandramohan, T.P. Sastry. Preparation and characterization of nanobiocomposites containing iron nanoparticles prepared from blood and coated with chitosan and gelatin. Materials Research Bulletin 2011, 46
(6)
, 901-904. https://doi.org/10.1016/j.materresbull.2011.02.021
- Quan Guo He, Zhao Hui Wu. Solvothermal Fabrication of Hollow Porous Magnetite Particles. Advanced Materials Research 2011, 183-185 , 1995-1999. https://doi.org/10.4028/www.scientific.net/AMR.183-185.1995
- Pengcheng Du, Peng Liu, Bin Mu, Yunjiao Wang. Monodisperse superparamagnetic pH‐sensitive single‐layer chitosan hollow microspheres with controllable structure. Journal of Polymer Science Part A: Polymer Chemistry 2010, 48
(22)
, 4981-4988. https://doi.org/10.1002/pola.24294
- Bin Mu, Peng Liu, Yun Dong, Chunyin Lu, Xueli Wu. Superparamagnetic pH‐sensitive multilayer hybrid hollow microspheres for targeted controlled release. Journal of Polymer Science Part A: Polymer Chemistry 2010, 48
(14)
, 3135-3144. https://doi.org/10.1002/pola.24095
- Ignác Capek. On inverse miniemulsion polymerization of conventional water-soluble monomers. Advances in Colloid and Interface Science 2010, 156
(1-2)
, 35-61. https://doi.org/10.1016/j.cis.2010.02.006
- Joëlle Aubin, Montse Ferrando, Vladimir Jiricny. Current methods for characterising mixing and flow in microchannels. Chemical Engineering Science 2010, 65
(6)
, 2065-2093. https://doi.org/10.1016/j.ces.2009.12.001
- Hongxia Liu, Chaoyang Wang, Quanxing Gao, Xinxing Liu, Zhen Tong. Magnetic hydrogels with supracolloidal structures prepared by suspension polymerization stabilized by Fe2O3 nanoparticles. Acta Biomaterialia 2010, 6
(1)
, 275-281. https://doi.org/10.1016/j.actbio.2009.06.018
- Hassan Masoud, Alexander Alexeev. Modeling magnetic microcapsules that crawl in microchannels. Soft Matter 2010, 6
(4)
, 794-799. https://doi.org/10.1039/B916835D
- Xuan Feng, Ying Yi, Xu Yu, Dai-Wen Pang, Zhi-Ling Zhang. Generation of water–ionic liquid droplet pairs in soybean oil on microfluidic chip. Lab Chip 2010, 10
(3)
, 313-319. https://doi.org/10.1039/B918167A
- Quanxing Gao, Chaoyang Wang, Hongxia Liu, Yunhua Chen, Zhen Tong. Dual nanocomposite multihollow polymer microspheres prepared by suspension polymerization based on a multiple pickering emulsion. Polym. Chem. 2010, 1
(1)
, 75-77. https://doi.org/10.1039/B9PY00255C
- Song Yang, Huarong Liu, Haofeng Huang, Zhicheng Zhang. Fabrication of superparamagnetic magnetite/poly(styrene-co-12-acryloxy-9-octadecenoic acid) nanocomposite microspheres with controllable structure. Journal of Colloid and Interface Science 2009, 338
(2)
, 584-590. https://doi.org/10.1016/j.jcis.2009.07.007
- Chun‐Xia Zhao, Anton P. J. Middelberg. Microfluidic Mass‐Transfer Control for the Simple Formation of Complex Multiple Emulsions. Angewandte Chemie 2009, 121
(39)
, 7344-7347. https://doi.org/10.1002/ange.200902485
- Chun‐Xia Zhao, Anton P. J. Middelberg. Microfluidic Mass‐Transfer Control for the Simple Formation of Complex Multiple Emulsions. Angewandte Chemie International Edition 2009, 48
(39)
, 7208-7211. https://doi.org/10.1002/anie.200902485
- Weisi Yin, M.Z. Yates. Encapsulation and sustained release from biodegradable microcapsules made by emulsification/freeze drying and spray/freeze drying. Journal of Colloid and Interface Science 2009, 336
(1)
, 155-161. https://doi.org/10.1016/j.jcis.2009.03.065
- Hongxia Liu, Chaoyang Wang, Quanxing Gao, Jianxin Chen, Biye Ren, Xinxing Liu, Zhen Tong. Facile fabrication of well-defined hydrogel beads with magnetic nanocomposite shells. International Journal of Pharmaceutics 2009, 376
(1-2)
, 92-98. https://doi.org/10.1016/j.ijpharm.2009.04.031
- Rong Lu, Hongjing Dou, Yuanyuan Qiu, Dong Zhang, Kang Sun, Yuqi Zhang, Kun Sun. Polymeric microcapsules with internal cavities for ultrasonic imaging: efficient fabrication and physical characterization. Colloid and Polymer Science 2009, 287
(6)
, 683-693. https://doi.org/10.1007/s00396-009-2014-3
- Yan Li, Jiafu Chen, Aping Niu, Fengfeng Xue, Yanxia Cao, Qun Xu. Preparation of hollow poly (styrene-co-divinylbenzene) particles with variable cavity sizes and further fabrication of hollow TiO2 particles using solid poly (styrene-co-divinylbenzene) particles as templates. Colloids and Surfaces A: Physicochemical and Engineering Aspects 2009, 342
(1-3)
, 107-114. https://doi.org/10.1016/j.colsurfa.2009.04.021
- Guangyu Liu, Hui Wang, Xinlin Yang. Synthesis of pH-sensitive hollow polymer microspheres with movable magnetic core. Polymer 2009, 50
(12)
, 2578-2586. https://doi.org/10.1016/j.polymer.2009.04.002
- Hongxia Liu, Chaoyang Wang, Quanxing Gao, Jianxin Chen, Xinxing Liu, Zhen Tong. One-pot fabrication of magnetic nanocomposite microcapsules. Materials Letters 2009, 63
(11)
, 884-886. https://doi.org/10.1016/j.matlet.2009.01.034
- Eun Mi Lee, Hyun Woo Lee, Jae Hyeung Park, Young A. Han, Byung Chul Ji, Weontae Oh, Yulin Deng, Jeong Hyun Yeum. Multihollow structured poly(methyl methacrylate)/silver nanocomposite microspheres prepared by suspension polymerization in the presence of dual dispersion agents. Colloid and Polymer Science 2008, 286
(12)
, 1379-1385. https://doi.org/10.1007/s00396-008-1907-x
- Song Yang, Huarong Liu, Zhicheng Zhang. A facile route to hollow superparamagnetic magnetite/polystyrene nanocomposite microspheres via inverse miniemulsion polymerization. Journal of Polymer Science Part A: Polymer Chemistry 2008, 46
(12)
, 3900-3910. https://doi.org/10.1002/pola.22700
- Sinoj Abraham, Yun Hwan Park, Jin Kyu Lee, Chang‐Sik Ha, Il Kim. Microfluidic Synthesis of Reversibly Swelling Porous Polymeric Microcapsules with Controlled Morphology. Advanced Materials 2008, 20
(11)
, 2177-2182. https://doi.org/10.1002/adma.200700456
- Dae Kun Hwang, Dhananjay Dendukuri, Patrick S. Doyle. Microfluidic-based synthesis of non-spherical magnetic hydrogel microparticles. Lab on a Chip 2008, 8
(10)
, 1640. https://doi.org/10.1039/b805176c
- Soon-Ryoung Hur, Yong Seok Kim, Jong Chan Won, Jae Heung Lee, Hyun Min Jung. Hollow hybrid spheres with silica inner shell for non-deformable, core exchangeable properties. Chemical Communications 2008, 43
(42)
, 5405. https://doi.org/10.1039/b811724a
- Liang‐Yin Chu, Andrew S. Utada, Rhutesh K. Shah, Jin‐Woong Kim, David A. Weitz. Controllable Monodisperse Multiple Emulsions. Angewandte Chemie International Edition 2007, 46
(47)
, 8970-8974. https://doi.org/10.1002/anie.200701358
- Liang‐Yin Chu, Andrew S. Utada, Rhutesh K. Shah, Jin‐Woong Kim, David A. Weitz. Controllable Monodisperse Multiple Emulsions. Angewandte Chemie 2007, 119
(47)
, 9128-9132. https://doi.org/10.1002/ange.200701358
- G. Guan, Z. Zhang, Z. Wang, B. Liu, D. Gao, C. Xie. Single‐Hole Hollow Polymer Microspheres toward Specific High‐Capacity Uptake of Target Species. Advanced Materials 2007, 19
(17)
, 2370-2374. https://doi.org/10.1002/adma.200700984
- Chaoyang Wang, Hongxia Liu, Quanxing Gao, Xinxing Liu, Zhen Tong. Facile Fabrication of Hybrid Colloidosomes with Alginate Gel Cores and Shells of Porous CaCO
3
Microparticles. ChemPhysChem 2007, 8
(8)
, 1157-1160. https://doi.org/10.1002/cphc.200700147
- N.S. John, N.R. Selvi, G.U. Kulkarni, S. Heun, E. Cavaliere, M. Fanetti, I. Kholmanov, L. Gavioli, M. Sancrotti. Transformation of femtoliter metal cups to oxide cups: chemical mapping by scanning Auger spectroscopy. Applied Physics A 2007, 87
(4)
, 683-689. https://doi.org/10.1007/s00339-007-3987-8
- Yuliang Wang, Thurston Herricks, Marta Ibisate, Pedro H.C. Camargo, Younan Xia. Synthesis and characterization of monodisperse colloidal spheres of Pb containing superparamagnetic Fe3O4 nanoparticles. Chemical Physics Letters 2007, 436
(1-3)
, 213-217. https://doi.org/10.1016/j.cplett.2007.01.046
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