Article

The Sonogashira Reaction:  A Booming Methodology in Synthetic Organic Chemistry

Departamento de Química Orgánica and Instituto de Síntesis Orgánica (ISO), Universidad de Alicante, Facultad de Ciencias, Apartado 99, 03080 Alicante, Spain
Chem. Rev., 2007, 107 (3), pp 874–922
DOI: 10.1021/cr050992x
Publication Date (Web): February 17, 2007
Copyright © 2007 American Chemical Society

Rafael Chinchilla (right) was born in Alicante and studied chemistry at the University of Alicante, from which he received B.S. (1985) and Ph.D. (1990) degrees. After a postdoctoral stay at the University of Uppsala, Sweden (1991−1992), he moved back to the University of Alicante, where he was appointed Associate Professor in 1997. He is coauthor of 70 papers and four patents. He is cofounder of the new chemical company MEDALCHEMY, S. L. as a spin-off of the University of Alicante. His current research interests include asymmetric synthesis, amino acid and peptide synthesis, and solid-supported reagents.

Carmen Nájera (left) was born in Nájera (La Rioja). She graduated from the University of Zaragoza in 1973 and obtained her doctorate in chemistry from the University of Oviedo in 1979, followed by postdoctoral stays at the ETH (Zurich), the Dyson Perrins Laboratory (Oxford), Harvard University, and Uppsala University. She became Associate Professor in 1985 at the University of Oviedo and Full Professor in 1993 at the University of Alicante. She is coauthor of more than 200 papers and 30 reviews, and has been visiting professor at different universities, such as University of Arizona (Tucson, AZ, USA), Universidad Nacional del Sur (Bahia Blanca, Argentina), Université Louis Pasteur (Strassbourg, France), and Ecole Nationale Superiéure de Chimie de Paris (France). Prof. Nájera has received the 2006 Janssen Cilag Organic Chemistry Prize from the Spanish Royal Chemical Society of Chemistry and the 2006 Rosalind Franklin International Lectureship from the English Royal Society. She is cofounder of the new chemical company MEDALCHEMY, S. L. as a spin-off of the University of Alicante. Her current research interest is focused on sulfones, amino acids, polymer-supported reagents, asymmetric catalysis, and palladium catalysis.

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Received 25 September 2006
Published online 17 February 2007
Published in print 1 March 2007
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