Communication

DNA Prism Structures Constructed by Folding of Multiple Rectangular Arms

Institute for Integrated Cell-Material Sciences (iCeMS) and Department of Chemistry, Graduate School of Science, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto 606-8502, Japan, CREST, Japan Science and Technology Corporation (JST), Sanbancho, Chiyoda-ku, Tokyo 102-0075, Japan, and Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan
J. Am. Chem. Soc., 2009, 131 (43), pp 15570–15571
DOI: 10.1021/ja904252e
Publication Date (Web): October 13, 2009
Copyright © 2009 American Chemical Society
endo@kuchem.kyoto-u.ac.jp; hs@kuchem.kyoto-u.ac.jp, †

Institute for Integrated Cell-Material Sciences, Kyoto University.

, §

Japan Science and Technology Corporation.

, ‡

Department of Chemistry, Graduate School of Science, Kyoto University.

, ∥

Osaka University.

Abstract

Abstract Image

Novel multiarm DNA structures were designed using two-dimensional DNA origami scaffolds, and these structures were folded into hollow three-dimensional (3D) structures by introducing connection strands into the arms. The opening of the prism structures was examined by high-speed AFM imaging, which showed the dissociation of the connecting arms in the 3D structures.

Experimental procedures and sequences of the DNA origami structures. This material is available free of charge via the Internet at http://pubs.acs.org.

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Article Views: 1,994 Times
Received 26 May 2009
Published online 13 October 2009
Published in print 4 November 2009
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