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Effect of Sesame Seeds Rich in Sesamin and Sesamolin on Fatty Acid Oxidation in Rat Liver

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National Food Research Institute, Ministry of Agriculture Forestry and Fisheries, 2-1-2 Kannondai, Tsukuba 305-8642, Japan; National Agriculture Research Center, Ministry of Agriculture Forestry and Fisheries, 2-1-2 Kannondai, Tsukuba 305-8666, Japan; and Chugoku National Agriculture Experimental Station, Ministry of Agriculture Forestry and Fisheries, Nishifukatsu 6-12-1, Fukuyama 721-8514, Japan
Cite this: J. Agric. Food Chem. 2001, 49, 5, 2647–2651
Publication Date (Web):April 6, 2001
Copyright © 2001 American Chemical Society

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    Activities of enzymes involved in hepatic fatty acid oxidation and synthesis among rats fed sesame (Sesamum indicum L.) differing in lignan content (sesamin and sesamolin) were compared. Sesame seeds rich in lignans from two lines, 0730 and 0732, lines established in this laborary, and those from a conventional cultivar (Masekin) were employed. Seeds from the 0730 and 0732 lines contained sesamin and sesamolin at amounts twice those from Masekin. Sesame seeds were added at levels of 200 g/kg to the experimental diets. Sesame increased both the hepatic mitochondrial and the peroxisomal fatty acid oxidation rate. Increases were greater with sesame rich in lignans than with Maskin. Noticeably, peroxisomal activity levels were >3 times higher in rats fed diets containing sesame seeds from the 0730 and 0732 lines than in those fed a control diet without sesame. The diet containing Masekin seed caused only a 50% increase in the value, however. Diets containing seeds from the 0730 and 0732 lines, compared to the control and Masekin diets, also significantly increased the activity of hepatic fatty acid oxidation enzymes including acyl-CoA oxidase, carnitine palmitoyltranferase, 3-hydroxyacyl-CoA dehydrogenase, and 3-ketoacyl-CoA thiolase. In contrast, diets containing sesame lowered the activity of enzymes involved in fatty acid synthesis including fatty acid synthase, glucose-6-phosphate dehydrogenase, ATP-citrate lyase, and pyruvate kinase. No significant differences in enzyme activities were, however, seen among diets containing sesame from Masekin cultivar and lines 0730 and 0732. Serum triacylglycerol concentrations were lower in rats fed diets containing sesame from lines 0730 and 0732 than in those fed the control or Masekin diet. It is apparent that sesame rich in lignans more profoundly affects hepatic fatty acid oxidation and serum triacylglycerol levels. Therefore, consumption of sesame rich in lignans results in physiological activity to alter lipid metabolism in a potentially beneficial manner.

    Keywords: Sesame; lignans; hepatic fatty acid oxidation; serum lipids; rat

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     National Agriculture Research Center.

     Chugoku National Agriculture Experimental Station.


     National Food Research Institute.


     Corresponding author (telephone 81-298-38-8083; fax 81-298-38-7996; e-mail [email protected]).

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    15. Yiting Sun, Jingyi Ren, Siqi Zhu, Zhenao Zhang, Zihao Guo, Jiaqi An, Bowen Yin, Yuxia Ma. The Effects of Sesamin Supplementation on Obesity, Blood Pressure, and Lipid Profile: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Frontiers in Endocrinology 2022, 13
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    17. Amin F. Majdalawieh, Sarah Dalibalta, Sarah M. Yousef. Effects of sesamin on fatty acid and cholesterol metabolism, macrophage cholesterol homeostasis and serum lipid profile: A comprehensive review. European Journal of Pharmacology 2020, 885 , 173417.
    18. M. Bonesi, A. M. Saab, M. C. Tenuta, M. Leporini, M. J. Saab, M. R. Loizzo, R. Tundis. Screening of traditional Lebanese medicinal plants as antioxidants and inhibitors of key enzymes linked to type 2 diabetes. Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology 2020, 154 (5) , 656-662.
    19. Marzieh Mokhber, Seyyed Ali Keshavarz, Farzad Shidfar, Abbas Hadji Akhundi, Hamidreza Pouraliakbar, Zahra Nazem Bokaee, Kamal Azam, Masoumeh Jabbarifakher, Feridoun Noohi. WITHDRAWN ARTICLE: Effect of Sesame Lignan Supplementation on Carotid Intima-Media Thickness, Serum Lipid Profile, Serum VEGF, VCAM-1, ICAM-1 and vWF Levels in Cardiovascular Disease Patients. International Journal of Endocrinology and Metabolism 2020, 19 (1)
    20. . Studies on trait association and path co-efficient analysis of sesame (Sesamum sp.) for quantitative traits and oil quality parameters. ELECTRONIC JOURNAL OF PLANT BREEDING 2020, 18-24.
    21. Lucy Sun Hwang, Min‐Hsiung Lee, Nan‐Wei Su. Sesame Oil. 2020, 1-39.
    22. Seung-Hwa Baek, Myung-Gyun Kang, Daeui Park. Inhibitory Effect of Sesamolin on Melanogenesis in B16F10 Cells Determined by In Vitro and Molecular Docking Analyses. Current Pharmaceutical Biotechnology 2020, 21 (2) , 169-178.
    23. Ayesha Mushtaq, Muhammad Asif Hanif, Muhammad Adnan Ayub, Ijaz Ahmad Bhatti, Muhammad Idrees Jilani. Sesame. 2020, 601-615.
    24. Yihang Zhao, Qianxu Wang, Mengzhen Jia, Shangchen Fu, Junru Pan, Chuanqi Chu, Xiaoning Liu, Xuebo Liu, Zhigang Liu. (+)-Sesamin attenuates chronic unpredictable mild stress-induced depressive-like behaviors and memory deficits via suppression of neuroinflammation. The Journal of Nutritional Biochemistry 2019, 64 , 61-71.
    25. Niti Pathak, Asani Bhaduri, Ashwani K. Rai. Sesame: Bioactive Compounds and Health Benefits. 2019, 181-200.
    26. Xin Guo, Tao Zhang, Longkai Shi, Mengyue Gong, Jun Jin, Yu Zhang, Ruijie Liu, Ming Chang, Qingzhe Jin, Xingguo Wang. The relationship between lipid phytochemicals, obesity and its related chronic diseases. Food & Function 2018, 9 (12) , 6048-6062.
    27. Yumiko Nakatani, Yukie Yaguchi, Tomomi Komura, Masakazu Nakadai, Kenji Terao, Eriko Kage-Nakadai, Yoshikazu Nishikawa. Sesamin extends lifespan through pathways related to dietary restriction in Caenorhabditis elegans. European Journal of Nutrition 2018, 57 (3) , 1137-1146.
    28. Carolina Alves Cardoso, Gláucia Maria Moraes de Oliveira, Luciana de Almeida Vittori Gouveia, Annie Seixas Bello Moreira, Glorimar Rosa. The effect of dietary intake of sesame ( Sesamumindicum L .) derivatives related to the lipid profile and blood pressure: A systematic review. Critical Reviews in Food Science and Nutrition 2018, 58 (1) , 116-125.
    29. Niti Pathak, Asani Bhaduri, Ashwani K Rai. Sesame: Bioactive Compounds and Health Benefits. 2018, 1-20.
    30. Mijeong Kim, Minji Woo, Jeong Sook Noh, Eunok Choe, Yeong Ok Song. Sesame oil lignans inhibit hepatic endoplasmic reticulum stress and apoptosis in high-fat diet-fed mice. Journal of Functional Foods 2017, 37 , 658-665.
    31. S. Gharby, H. Harhar, Z. Bouzoubaa, A. Asdadi, A. El Yadini, Z. Charrouf. Chemical characterization and oxidative stability of seeds and oil of sesame grown in Morocco. Journal of the Saudi Society of Agricultural Sciences 2017, 16 (2) , 105-111.
    32. Honoo Satake, Tomotsugu Koyama, Erika Matsumoto, Kinuyo Morimoto, Eiichiro Ono, Jun Murata. Metabolic Engineering of Lignan Biosynthesis Pathways for the Production of Transgenic Plant-Based Foods. 2017, 373-398.
    33. Honoo Satake, Akira Shiraishi, Tomotsugu Koyama, Erika Matsumoto, Kinuyo Morimoto, Sedigheh E. Bahabadi, Eiichiro Ono, Jun Murata. Lignan Biosynthesis for Food Bioengineering. 2017, 351-379.
    34. Vahid Rezaeipour, Alireza Barsalani, Rohullah Abdullahpour. Effects of phytase supplementation on growth performance, jejunum morphology, liver health, and serum metabolites of Japanese quails fed sesame (Sesamum indicum) meal-based diets containing graded levels of protein. Tropical Animal Health and Production 2016, 48 (6) , 1141-1146.
    35. Saman Khalesi, Ernesta Paukste, Elham Nikbakht, Hossein Khosravi-Boroujeni. Sesame fractions and lipid profiles: a systematic review and meta-analysis of controlled trials. British Journal of Nutrition 2016, 115 (5) , 764-773.
    36. Honoo Satake, Tomotsugu Koyama, Erika Matsumoto, Kinuyo Morimoto, Eiichiro Ono, Jun Murata. Metabolic Engineering of Lignan Biosynthesis Pathways for the Production of Transgenic Plant-Based Foods. 2016, 1-26.
    37. Jun Murata, Erika Matsumoto, Kinuyo Morimoto, Tomotsugu Koyama, Honoo Satake, . Generation of Triple-Transgenic Forsythia Cell Cultures as a Platform for the Efficient, Stable, and Sustainable Production of Lignans. PLOS ONE 2015, 10 (12) , e0144519.
    38. Yun Hee Kim, Hye Lim Lee. Therapeutic Effects of Sesamum Indicum Extracts on Atopic Dermatitis-Like Skin Lesions of NC/Nga Mouce. The Journal of Korean Oriental Pediatrics 2015, 29 (4) , 39-66.
    39. Mohammad Ali Nasseri, Saeideh Sharifi Bigy, Ali Allahresani, Mohammad Malekaneh. Assessment of Antioxidant Activity, Chemical Characterization and Evaluation of Fatty Acid Compositions of Scorzonera Paradoxa Fisch and C. A. Mey. Jundishapur Journal of Natural Pharmaceutical Products 2015, 10 (4)
    40. Vasundhra Shukla, Prameela Kandra. Development, physico-chemical and sensory evaluation of natural nutra candy. Journal of Food Science and Technology 2015, 52 (11) , 7535-7539.
    41. N. Pathak, A. Bhaduri, K.V. Bhat, A.K. Rai, . Tracking sesamin synthase gene expression through seed maturity in wild and cultivated sesame species – a domestication footprint. Plant Biology 2015, 17 (5) , 1039-1046.
    42. Honoo Satake, Tomotsugu Koyama, Sedigheh Bahabadi, Erika Matsumoto, Eiichiro Ono, Jun Murata. Essences in Metabolic Engineering of Lignan Biosynthesis. Metabolites 2015, 5 (2) , 270-290.
    43. Takashi Ide, Ayana Azechi, Sayaka Kitade, Yoko Kunimatsu, Natsuko Suzuki, Chihiro Nakajima, Naoki Ogata. Comparative Effects of Sesame Seeds Differing in Lignan Contents and Composition on Fatty Acid Oxidation in Rat Liver. Journal of Oleo Science 2015, 64 (2) , 211-222.
    44. Yun Sik Nam, Kown-Chul Noh, Eun Joo Roh, Gyochang Keum, Yeonhee Lee, Kang-Bong Lee. Determination of Edible Vegetable Oil Adulterants in Sesame Oil Using 1 H Nuclear Magnetic Resonance Spectroscopy. Analytical Letters 2014, 47 (7) , 1190-1200.
    45. Peraphan Pothacharoen, Sumet Najarus, Jongkolnee Settakorn, Shuji Mizumoto, Kazuyuki Sugahara, Prachya Kongtawelert. Effects of sesamin on the biosynthesis of chondroitin sulfate proteoglycans in human articular chondrocytes in primary culture. Glycoconjugate Journal 2014, 31 (3) , 221-230.
    46. N.E. Mohamed, M.M. Wakwak. Effect of sesame seeds or oil supplementation to the feed on some physiological parameters in Japanese Quail. Journal of Radiation Research and Applied Sciences 2014, 7 (1) , 101-109.
    47. Danijela Ristic-Medic, Gordana Perunicic-Pekovic, Zorica Rasic-Milutinovic, Marija Takic, Tamara Popovic, Aleksandra Arsic, Marija Glibetic. Effects of Dietary Milled Seed Mixture on Fatty Acid Status and Inflammatory Markers in Patients on Hemodialysis. The Scientific World Journal 2014, 2014 , 1-9.
    48. Jia-Le Song, Jung-Ho Choi, Jae-Hoon Seo, Jeung-Ha Kil, Kun-Young Park. Antioxidative effects of fermented sesame sauce against hydrogen peroxide-induced oxidative damage in LLC-PK1 porcine renal tubule cells. Nutrition Research and Practice 2014, 8 (2) , 138.
    49. AnnaLotta Schiller Vestergren, Sofia Trattner, Jinfeng Pan, Pernilla Johnsson, Afaf Kamal-Eldin, Eva Brännäs, Ali A. Moazzami, Jana Pickova. The effect of combining linseed oil and sesamin on the fatty acid composition in white muscle and on expression of lipid-related genes in white muscle and liver of rainbow trout (Oncorhynchus mykiss). Aquaculture International 2013, 21 (4) , 843-859.
    50. Kequan Zhou, Yuting Zhou, Y. Martin Lo. Refining Food Processing By‐Products for Value‐Added Functional Ingredients. 2013, 441-448.
    51. Nitesh Kumar, Jayesh Mudgal, Vipan K. Parihar, Pawan G. Nayak, N. Gopalan Kutty, C. Mallikarjuna Rao. Sesamol Treatment Reduces Plasma Cholesterol and Triacylglycerol Levels in Mouse Models of Acute and Chronic Hyperlipidemia. Lipids 2013, 48 (6) , 633-638.
    52. V. Aparna, K. V. Dileep, C. Sadasivan, M. Haridas. Computational and thermodynamic analyses of the phospholipase A2 inhibition by erucic acid and linoleic acid. Medicinal Chemistry Research 2013, 22 (3) , 1102-1106.
    53. Sedigheh Asgary, Mahmoud Rafieian-Kopaei, Somayeh Najafi, Esfandiar Heidarian, Amirhossein Sahebkar. Antihyperlipidemic Effects of Sesamum indicum L. in Rabbits Fed a High-Fat Diet. The Scientific World Journal 2013, 2013 , 1-5.
    54. Ramez Alhazzaa, Andrew R. Bridle, Chris G. Carter, Peter D. Nichols. Sesamin modulation of lipid class and fatty acid profile in early juvenile teleost, Lates calcarifer, fed different dietary oils. Food Chemistry 2012, 134 (4) , 2057-2065.
    55. Beitollah Alipoor, Mahdieh Khadem Haghighian, Bina Eftekhar Sadat, Mohammad Asghari. Effect of sesame seed on lipid profile and redox status in hyperlipidemic patients. International Journal of Food Sciences and Nutrition 2012, 63 (6) , 674-678.
    56. Papiya Bigoniya, Ravi Nishad, Chandra Shekhar Singh. Preventive effect of sesame seed cake on hyperglycemia and obesity against high fructose-diet induced Type 2 diabetes in rats. Food Chemistry 2012, 133 (4) , 1355-1361.
    57. N. Shivhare, N. Satsangee. Wonders of Sesame: Nutraceutical Uses and Health Benefits. 2012, 63-68.
    58. T. K. Lim. Sesamum indicum. 2012, 187-219.
    59. CLIFFORD HALL. Other natural antioxidants – rice bran oil, sesame oil, rosemary extract, flavonoids. 2012, 73-112.
    60. S. Prakash Kochhar. Minor and Speciality Oils. 2011, 291-341.
    61. Kinuyo Morimoto, Hyun-Jung Kim, Eiichiro Ono, Akio Kobayashi, Atsushi Okazawa, Honoo Satake. Effects of light on production of endogenous and exogenous lignans by Forsythia koreana wildtype and transgenic cells. Plant Biotechnology 2011, 28 (3) , 331-337.
    62. J.H.Y. Wu, J.M. Hodgson, I.B. Puddey, R. Belski, V. Burke, K.D. Croft. Sesame supplementation does not improve cardiovascular disease risk markers in overweight men and women. Nutrition, Metabolism and Cardiovascular Diseases 2009, 19 (11) , 774-780.
    63. H. J. Kim, E. Ono, K. Morimoto, T. Yamagaki, A. Okazawa, A. Kobayashi, H. Satake. Metabolic Engineering of Lignan Biosynthesis in Forsythia Cell Culture. Plant and Cell Physiology 2009, 50 (12) , 2200-2209.
    64. Karen D. Coulman, Zhen Liu, John Michaelides, Winston Quan Hum, Lilian U. Thompson. Fatty acids and lignans in unground whole flaxseed and sesame seed are bioavailable but have minimal antioxidant and lipid‐lowering effects in postmenopausal women. Molecular Nutrition & Food Research 2009, 53 (11) , 1366-1375.
    65. Tae-Shik Hahm, Sung-Jin Park, Y. Martin Lo. Effects of germination on chemical composition and functional properties of sesame (Sesamum indicum L.) seeds. Bioresource Technology 2009, 100 (4) , 1643-1647.
    66. Ali Moazzami, Afaf Kamal-Eldin. Sesame Seed Oil. 2009, 267-282.
    67. Takashi IDE, Jin Seon LIM, Tseye-Oidov ODBAYAR, Yasutaka NAKASHIMA. Comparative Study of Sesame Lignans (Sesamin, Episesamin and Sesamolin) Affecting Gene Expression Profile and Fatty Acid Oxidation in Rat Liver. Journal of Nutritional Science and Vitaminology 2009, 55 (1) , 31-43.
    68. Yoko Takahashi, Takashi Ide. Effects of soy protein and isoflavone on hepatic fatty acid synthesis and oxidation and mRNA expression of uncoupling proteins and peroxisome proliferator-activated receptor γ in adipose tissues of rats. The Journal of Nutritional Biochemistry 2008, 19 (10) , 682-693.
    69. Mitsuo Namiki. Nutraceutical Functions of Sesame: A Review. Critical Reviews in Food Science and Nutrition 2007, 47 (7) , 651-673.
    70. Bor-Sen Wang, Lee-Wen Chang, Wen-Jye Yen, Pin-Der Duh. Antioxidative effect of sesame coat on LDL oxidation and oxidative stress in macrophages. Food Chemistry 2007, 102 (1) , 351-360.
    71. Wieland Peschel, Wilfried Dieckmann, Marlies Sonnenschein, Andreas Plescher. High antioxidant potential of pressing residues from evening primrose in comparison to other oilseed cakes and plant antioxidants. Industrial Crops and Products 2007, 25 (1) , 44-54.
    72. Jin Seon Lim, Yoshikazu Adachi, Yoko Takahashi, Takashi Ide. Comparative analysis of sesame lignans (sesamin and sesamolin) in affecting hepatic fatty acid metabolism in rats. British Journal of Nutrition 2007, 97 (1) , 85-95.
    73. Shylesh Bhaskaran, Nalini Santanam, Meera Penumetcha, Sampath Parthasarathy. Inhibition of Atherosclerosis in Low-Density Lipoprotein Receptor-Negative Mice by Sesame Oil. Journal of Medicinal Food 2006, 9 (4) , 487-490.
    74. Jinyoung Lee, Eunok Choe. Extraction of Lignan Compounds from Roasted Sesame Oil and their Effects on the Autoxidation of Methyl Linoleate. Journal of Food Science 2006, 71 (7)
    75. Eiichiro Ono, Masaaki Nakai, Yuko Fukui, Namino Tomimori, Masako Fukuchi-Mizutani, Masayuki Saito, Honoo Satake, Takaharu Tanaka, Masumi Katsuta, Toshiaki Umezawa, Yoshikazu Tanaka. Formation of two methylenedioxy bridges by a Sesamum CYP81Q protein yielding a furofuran lignan, (+)-sesamin. Proceedings of the National Academy of Sciences 2006, 103 (26) , 10116-10121.
    76. Kinuko Ishiyama, Mayumi Nagashima, Tomoko Yasumoto, Yasuko Fukuda. Changes in Amounts of Lignan Compounds and Radical Scavenging Activities in Improved High-Lignan Breed of Sesame, “Gomazou”, during Germination. NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI 2006, 53 (1) , 8-16.
    77. Satoko YASUMOTO, Masumi KATSUTA. Breeding a High-Lignan-Content Sesame Cultivar in the Prospect of Promoting Metabolic Functionality. Japan Agricultural Research Quarterly: JARQ 2006, 40 (2) , 123-129.
    78. Lilian Thompson. Flaxseed, Lignans, n-3 Fatty Acids, and Drug Synergy in the Prevention and Treatment of Cancer. 2005, 147-173.
    79. Lucy Sun Hwang. Sesame Oil. 2005
    80. Karen D. Coulman, Zhen Liu, Winston Quan Hum, John Michaelides, Lilian U. Thompson. Whole Sesame Seed Is as Rich a Source of Mammalian Lignan Precursors as Whole Flaxseed. Nutrition and Cancer 2005, 52 (2) , 156-165.
    81. Takashi Ide, Dang Diem Hong, Pathmasiri Ranasinghe, Yoko Takahashi, Masayo Kushiro, Michihiro Sugano. Interaction of dietary fat types and sesamin on hepatic fatty acid oxidation in rats. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 2004, 1682 (1-3) , 80-91.
    82. . Sesamum indicum. , 487-505.

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