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Investigations of Factors That Influence the Acrylamide Content of Heated Foodstuffs

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Department of Environmental Chemistry, Stockholm University, S-106 91 Stockholm, Sweden, and AnalyCen Nordic AB, Box 905, S-531 19 Lidköping, Sweden
Cite this: J. Agric. Food Chem. 2003, 51, 24, 7012–7018
Publication Date (Web):October 18, 2003
https://doi.org/10.1021/jf034649+
Copyright © 2003 American Chemical Society

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    Abstract

    The acrylamide content of heated foodstuffs should be considered to be the net result of complex reactions leading to the formation and elimination/degradation of this compound. The present study, involving primarily homogenized potato heated in an oven, was designed to characterize parameters that influence these reactions, including the heating temperature, duration of heating, pH, and concentrations of various components. Higher temperature (200 °C) combined with prolonged heating times produced reduced levels of acrylamide, due to elimination/degradation processes. At certain concentrations the presence of asparagine or monosaccharides (in particular, fructose and also glucose and glyceraldehyde) was found to increase the net content of acrylamide. Addition of other free amino acids or a protein-rich food component strongly reduced the acrylamide content, probably by promoting competing reactions and/or covalently binding acrylamide formed. The dependence on pH of the acrylamide content exhibited a maximum around pH 8; in particular, lower pH was shown to enhance elimination and decelerate formation of acrylamide. In contrast, the effects of additions of antioxidants or peroxides on acrylamide content were small or nonexistent.

    Keywords: Acrylamide; cooking; heating; food; potato; Maillard reaction

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     Stockholm University.

     AnalyCen Nordic AB.

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     Author to whom correspondence should be addressed (telephone +46-8-162000; fax +46-8-163979; e-mail [email protected]).

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    3. Antonio Dario Troise, Alberto Fiore, and Vincenzo Fogliano . Quantitation of Acrylamide in Foods by High-Resolution Mass Spectrometry. Journal of Agricultural and Food Chemistry 2014, 62 (1) , 74-79. https://doi.org/10.1021/jf404205b
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    8. Yu Zhang, Yiping Ren and Ying Zhang. New Research Developments on Acrylamide: Analytical Chemistry, Formation Mechanism, and Mitigation Recipes. Chemical Reviews 2009, 109 (9) , 4375-4397. https://doi.org/10.1021/cr800318s
    9. Micha Peleg, Maria G. Corradini and Mark D. Normand . Isothermal and Non-isothermal Kinetic Models of Chemical Processes in Foods Governed by Competing Mechanisms. Journal of Agricultural and Food Chemistry 2009, 57 (16) , 7377-7386. https://doi.org/10.1021/jf9012423
    10. Robert A. Levine and Sean M. Ryan. Determining the Effect of Calcium Cations on Acrylamide Formation in Cooked Wheat Products Using a Model System. Journal of Agricultural and Food Chemistry 2009, 57 (15) , 6823-6829. https://doi.org/10.1021/jf901120m
    11. Gema Arribas-Lorenzo and Francisco J. Morales. Effect of Pyridoxamine on Acrylamide Formation in a Glucose/Asparagine Model System. Journal of Agricultural and Food Chemistry 2009, 57 (3) , 901-909. https://doi.org/10.1021/jf802870t
    12. J. Stephen Elmore, Jane K. Parker, Nigel G. Halford, Nira Muttucumaru and Donald S. Mottram. Effects of Plant Sulfur Nutrition on Acrylamide and Aroma Compounds in Cooked Wheat. Journal of Agricultural and Food Chemistry 2008, 56 (15) , 6173-6179. https://doi.org/10.1021/jf0730441
    13. Rosario Zamora and Francisco J. Hidalgo. Contribution of Lipid Oxidation Products to Acrylamide Formation in Model Systems. Journal of Agricultural and Food Chemistry 2008, 56 (15) , 6075-6080. https://doi.org/10.1021/jf073047d
    14. Mendel Friedman and Carol E. Levin. Review of Methods for the Reduction of Dietary Content and Toxicity of Acrylamide. Journal of Agricultural and Food Chemistry 2008, 56 (15) , 6113-6140. https://doi.org/10.1021/jf0730486
    15. Frédéric Mestdagh, Pieter Castelein, Carlos Van Peteghem and Bruno De Meulenaer. Importance of Oil Degradation Components in the Formation of Acrylamide in Fried Foodstuffs. Journal of Agricultural and Food Chemistry 2008, 56 (15) , 6141-6144. https://doi.org/10.1021/jf073049y
    16. Craig Mills, Christina Tlustos, Rhodri Evans and Wendy Matthews. Dietary Acrylamide Exposure Estimates for the United Kingdom and Ireland: Comparison between Semiprobabilistic and Probabilistic Exposure Models. Journal of Agricultural and Food Chemistry 2008, 56 (15) , 6039-6045. https://doi.org/10.1021/jf073050x
    17. Guy A. Channell, Florian Wulfert and Andrew J. Taylor. Identification and Monitoring of Intermediates and Products in the Acrylamide Pathway Using Online Analysis. Journal of Agricultural and Food Chemistry 2008, 56 (15) , 6097-6104. https://doi.org/10.1021/jf7037423
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    19. Aurora Napolitano, Francisco Morales, Raffaele Sacchi and Vincenzo Fogliano. Relationship between Virgin Olive Oil Phenolic Compounds and Acrylamide Formation in Fried Crisps. Journal of Agricultural and Food Chemistry 2008, 56 (6) , 2034-2040. https://doi.org/10.1021/jf0730082
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    21. Vandana Verma, Neelam Yadav. Effect of plant extracts on the reduction of acrylamide and hydroxymethylfurfural formation in French fries. Food Chemistry Advances 2024, 4 , 100708. https://doi.org/10.1016/j.focha.2024.100708
    22. Pei-Tjun Edna Hee, Zijian Liang, Pangzhen Zhang, Zhongxiang Fang. Formation mechanisms, detection methods and mitigation strategies of acrylamide, polycyclic aromatic hydrocarbons and heterocyclic amines in food products. Food Control 2024, 158 , 110236. https://doi.org/10.1016/j.foodcont.2023.110236
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    27. Ying Zhang, Cheng Jin. Relationship between antioxidants and acrylamide formation. 2024, 403-432. https://doi.org/10.1016/B978-0-323-99119-3.00013-8
    28. Aytül Hamzalıoğlu, Vural Gökmen. Reactions of acrylamide during digestions of thermally processed foods. 2024, 351-369. https://doi.org/10.1016/B978-0-323-99119-3.00028-X
    29. Vural Gökmen. Introduction: potential safety risks associated with thermal processing of foods. 2024, xix-xxv. https://doi.org/10.1016/B978-0-323-99119-3.02001-4
    30. Neslihan Göncüoğlu Taş, Vural Gökmen. Multiresponse kinetic modeling of acrylamide formation in foods. 2024, 331-350. https://doi.org/10.1016/B978-0-323-99119-3.00025-4
    31. Slađana Žilić. Acrylamide in soybean products, roasted nuts, and dried fruits. 2024, 201-222. https://doi.org/10.1016/B978-0-323-99119-3.00026-6
    32. Vural Gökmen. Acrylamide in Thermally Processed Potato Products. Potato Research 2023, 66 (4) , 1315-1329. https://doi.org/10.1007/s11540-023-09634-8
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    41. Eileen Abt, Victoria Incorvati, Lauren Posnick Robin. Acrylamide: perspectives from international, national, and regional exposure assessments. Current Opinion in Food Science 2022, 47 , 100891. https://doi.org/10.1016/j.cofs.2022.100891
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    57. Huihui Hu, Xiaoling Liu, Lian Jiang, Qi Zhang, Haide Zhang. The relationship between acrylamide and various components during coffee roasting and effect of amino acids on acrylamide formation. Journal of Food Processing and Preservation 2021, 43 https://doi.org/10.1111/jfpp.15421
    58. Jaime Amaya-Farfan, Delia B. Rodriguez-Amaya. The Maillard reactions. 2021, 215-263. https://doi.org/10.1016/B978-0-12-817380-0.00006-3
    59. Maria Beatriz Abreu Gloria, Lilia Masson, Jaime Amaya-Farfan, Delia B. Rodriguez-Amaya. Generation of process-induced toxicants. 2021, 453-535. https://doi.org/10.1016/B978-0-12-817380-0.00010-5
    60. Dilumi W.K. Liyanage, Dmytro P. Yevtushenko, Michele Konschuh, Benoît Bizimungu, Zhen-Xiang Lu. Processing strategies to decrease acrylamide formation, reducing sugars and free asparagine content in potato chips from three commercial cultivars. Food Control 2021, 119 , 107452. https://doi.org/10.1016/j.foodcont.2020.107452
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    63. Burçe Ataç Mogol, Aytül Hamzalıoğlu, Vural Gökmen. Mitigation of Acrylamide in Thermally Processed Foods. 2021, 32-43. https://doi.org/10.1016/B978-0-08-100596-5.22827-8
    64. Aoi Takama, Hiroko Matsubara, Seon Hwa Lee, Tomoyuki Oe. Carnosine and anserine in chicken can quench toxic acrylamide under cooking conditions: Mass spectrometric studies on adduct formation and characterization. Food Chemistry 2020, 333 , 127480. https://doi.org/10.1016/j.foodchem.2020.127480
    65. Johannes Pitsch, Otmar Höglinger, Julian Weghuber. Roasted Rye as a Coffee Substitute: Methods for Reducing Acrylamide. Foods 2020, 9 (7) , 925. https://doi.org/10.3390/foods9070925
    66. Hyojin Jeong, Soomee Hwang, Hoonjeong Kwon. Survey for acrylamide in processed foods from Korean market and individual exposure estimation using a non-parametric probabilistic model. Food Additives & Contaminants: Part A 2020, 37 (6) , 916-930. https://doi.org/10.1080/19440049.2020.1746410
    67. Thomas Swift. pH Dependence of Acrylate-Derivative Polyelectrolyte Properties. 2020https://doi.org/10.5772/intechopen.82569
    68. Der-Sheng Chan. Computer Simulation with a Temperature-Step Frying Approach to Mitigate Acrylamide Formation in French Fries. Foods 2020, 9 (2) , 200. https://doi.org/10.3390/foods9020200
    69. Robert Sevenich, Cornelia Rauh, Beverly Belkova, Jana Hajslova. Effect of high-pressure thermal sterilization (HPTS) on the reduction of food processing contaminants (e.g., furan, acrylamide, 3-MCPD-esters, HMF). 2020, 139-172. https://doi.org/10.1016/B978-0-12-816405-1.00006-6
    70. Atsushi Kobayashi, Satoko Gomikawa, Asami Oguro, Satoshi Maeda, Akira Yamazaki, Shinji Sato, Hirofumi Maekawa. Effects on Acrylamide Generation under Heating Conditions by Addition of Lysine and Cysteine to Non-centrifugal Cane Sugar. Food Science and Technology Research 2020, 26 (5) , 673-680. https://doi.org/10.3136/fstr.26.673
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    72. Hugo Streekstra, Andy Livingston. Acrylamide in bread and baked products. 2020, 289-321. https://doi.org/10.1016/B978-0-08-102519-2.00010-4
    73. Eileen Abt, Lauren Posnick Robin, Sara McGrath, Jannavi Srinivasan, Michael DiNovi, Yoko Adachi, Stuart Chirtel. Acrylamide levels and dietary exposure from foods in the United States, an update based on 2011-2015 data. Food Additives & Contaminants: Part A 2019, 36 (10) , 1475-1490. https://doi.org/10.1080/19440049.2019.1637548
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    76. Suman, Generotti, Cirlini, Dall’Asta. Acrylamide Reduction Strategy in Combination with Deoxynivalenol Mitigation in Industrial Biscuits Production. Toxins 2019, 11 (9) , 499. https://doi.org/10.3390/toxins11090499
    77. Katharina Goerke, Meike Ruenz, Alfonso Lampen, Klaus Abraham, Tamara Bakuradze, Gerhard Eisenbrand, Elke Richling. Biomonitoring of nutritional acrylamide intake by consumers without dietary preferences as compared to vegans. Archives of Toxicology 2019, 93 (4) , 987-996. https://doi.org/10.1007/s00204-019-02412-x
    78. . Improving the Quality of Fried Foods. 2019, 407-445. https://doi.org/10.1002/9781119468417.ch13
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    80. Yuan Yuan, Fang Chen. Acrylamide. 2019, 47-85. https://doi.org/10.1007/978-981-13-8118-8_3
    81. Aytül Hamzalıoğlu, Burçe Ataç Mogol, Vural Gökmen. Acrylamide: An Overview of the Chemistry and Occurrence in Foods. 2019, 492-499. https://doi.org/10.1016/B978-0-08-100596-5.21817-9
    82. Emine Tanış, Nevin Çankaya, Serap Yalçın. Synthesis, Characterization, Computation of Global Reactivity Descriptors and Antiproliferative Activity of N-(4-nitrophenyl)Acrylamide. Russian Journal of Physical Chemistry B 2019, 13 (1) , 49-61. https://doi.org/10.1134/S1990793119010147
    83. Rehab Mohamed Ibrahim, Isis Nawar, Mokhtar Ibrahim Yousef, Mahmoud Ibrahim El-Sayed, Amal Hassanein. Protective Role of Natural Antioxidants Against the Formation and Harmful Effects of Acrylamide in Food. Trends in Applied Sciences Research 2019, 14 (1) , 41-55. https://doi.org/10.3923/tasr.2019.41.55
    84. A. Antunes-Rohling, S. Ciudad-Hidalgo, J. Mir-Bel, J. Raso, G. Cebrián, I. Álvarez. Ultrasound as a pretreatment to reduce acrylamide formation in fried potatoes. Innovative Food Science & Emerging Technologies 2018, 49 , 158-169. https://doi.org/10.1016/j.ifset.2018.08.010
    85. Mohammad Namir, Mohamed A. Rabie, Nourhan A. Rabie, Mohamed Fawzy Ramadan. Optimizing the Addition of Functional Plant Extracts and Baking Conditions To Develop Acrylamide-Free Pita Bread. Journal of Food Protection 2018, 81 (10) , 1696-1706. https://doi.org/10.4315/0362-028X.JFP-18-150
    86. Gurunathan Baskar, Ravi Aiswarya. Overview on mitigation of acrylamide in starchy fried and baked foods. Journal of the Science of Food and Agriculture 2018, 98 (12) , 4385-4394. https://doi.org/10.1002/jsfa.9013
    87. Sreenivasulu Dasari, Muni Swamy Ganjayi, Balaji Meriga. Glutathione S-transferase is a good biomarker in acrylamide induced neurotoxicity and genotoxicity. Interdisciplinary Toxicology 2018, 11 (2) , 115-121. https://doi.org/10.2478/intox-2018-0007
    88. Hengameh Dortaj, , Morteza Anvari, , Maryam Yadegari, , Mohammad Hosseini Sharifabad, , Abolghasem Abbasi Sarcheshmeh, . Stereological Survey of the Effect of Vitamin C on Neonatal Rat Kidney Tissue Treated With Acrylamide. Modern Medical Laboratory Journal 2018, 1 (2) , 42-49. https://doi.org/10.30699/mmlj17.1.2.42
    89. Asmaa Al-Asmar, Daniele Naviglio, Concetta Valeria L. Giosafatto, Loredana Mariniello. Hydrocolloid-Based Coatings are Effective at Reducing Acrylamide and Oil Content of French Fries. Coatings 2018, 8 (4) , 147. https://doi.org/10.3390/coatings8040147
    90. Andres Elias, Mati Roasto, Mari Reinik, Keiu Nelis, Eha Nurk, Terje Elias. Acrylamide in commercial foods and intake by infants in Estonia. Food Additives & Contaminants: Part A 2017, 34 (11) , 1875-1884. https://doi.org/10.1080/19440049.2017.1347283
    91. Elena Bartkiene, Donata Vizbickiene, Vadims Bartkevics, Iveta Pugajeva, Vita Krungleviciute, Daiva Zadeike, Paulina Zavistanaviciute, Grazina Juodeikiene. Application of Pediococcus acidilactici LUHS29 immobilized in apple pomace matrix for high value wheat-barley sourdough bread. LWT - Food Science and Technology 2017, 83 , 157-164. https://doi.org/10.1016/j.lwt.2017.05.010
    92. Fernanda Furlan Gonçalves Dias, Stanislau Bogusz Junior, Leandro Wang Hantao, Fábio Augusto, Hélia Harumi Sato. Acrylamide mitigation in French fries using native l-asparaginase from Aspergillus oryzae CCT 3940. LWT - Food Science and Technology 2017, 76 , 222-229. https://doi.org/10.1016/j.lwt.2016.04.017
    93. Franco Pedreschi, María Salomé Mariotti. Mitigation of Acrylamide Formation in Highly Consumed Foods. 2017, 357-375. https://doi.org/10.1007/978-1-4939-6496-3_19
    94. Vijay Paul, R. Ezekiel, Rakesh Pandey. Acrylamide in processed potato products: progress made and present status. Acta Physiologiae Plantarum 2016, 38 (12) https://doi.org/10.1007/s11738-016-2290-8
    95. Cécile Rannou, Delphine Laroque, Emilie Renault, Carole Prost, Thierry Sérot. Mitigation strategies of acrylamide, furans, heterocyclic amines and browning during the Maillard reaction in foods. Food Research International 2016, 90 , 154-176. https://doi.org/10.1016/j.foodres.2016.10.037
    96. Gaurav Sanghvi, Kapil Bhimani, Devendra Vaishnav, Tejas Oza, Gaurav Dave, Prashant Kunjadia, Navin Sheth. Mitigation of acrylamide by l-asparaginase from Bacillus subtilis KDPS1 and analysis of degradation products by HPLC and HPTLC. SpringerPlus 2016, 5 (1) https://doi.org/10.1186/s40064-016-2159-8
    97. Fei Xu, Maria-Jose Oruna-Concha, J. Stephen Elmore. The use of asparaginase to reduce acrylamide levels in cooked food. Food Chemistry 2016, 210 , 163-171. https://doi.org/10.1016/j.foodchem.2016.04.105
    98. M. Sansano, M.L. Castelló, A. Heredia, A. Andrés. Protective effect of chitosan on acrylamide formation in model and batter systems. Food Hydrocolloids 2016, 60 , 1-6. https://doi.org/10.1016/j.foodhyd.2016.03.017
    99. Yu-Wei Chang, Wen-Chieh Sung, Jing-Yi Chen. Effect of different molecular weight chitosans on the mitigation of acrylamide formation and the functional properties of the resultant Maillard reaction products. Food Chemistry 2016, 199 , 581-589. https://doi.org/10.1016/j.foodchem.2015.12.065
    100. Yuchen Zhu, Pengpu Wang, Fei Wang, Mengyao Zhao, Xiaosong Hu, Fang Chen. The kinetics of the inhibition of acrylamide by glycine in potato model systems. Journal of the Science of Food and Agriculture 2016, 96 (2) , 548-554. https://doi.org/10.1002/jsfa.7122
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