Anthocyanin and Flavonol Variation in Bog Bilberries (Vaccinium uliginosum L.) in FinlandClick to copy article linkArticle link copied!
Abstract
The flavonoids, anthocyanins and flavonols, in bog bilberries (Vaccinium uliginosum L.) were studied from 15 populations in Finland on a south−north axis of ∼1000 km. Four anthocyanidin xylosides and 14 flavonol glycosides were tentatively identified by means of HPLC−ESI-MS. Twenty-five major flavonoids were quantified by HPLC−DAD. The averages (±standard deviation) in the contents of anthocyanins and flavonols were 1425 ± 398 and 1133 ± 290 mg/100 g of dry weight, respectively. The most abundant anthocyanidin was malvidin, followed by delphinidin, petunidin, cyanidin, and peonidin. Quercetin was the major flavonol, followed by myricetin, laricitrin, syringetin, and isorhamnetin. Anthocyanins were mostly glucosides, whereas flavonols were mainly conjugated to galactose. The anthocyanin content in the berries from the south was the lowest. The delphinidin content was the highest but the proportion of malvidin the lowest in the north. The total flavonol content and the level of myricetin and quercetin were the highest in the north.
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- Wei Yang, Xueying Ma, Oskar Laaksonen, Wenjia He, Heikki Kallio, Baoru Yang. Effects of Latitude and Weather Conditions on Proanthocyanidins in Blackcurrant (Ribes nigrum) of Finnish Commercial Cultivars. Journal of Agricultural and Food Chemistry 2019, 67
(51)
, 14038-14047. https://doi.org/10.1021/acs.jafc.9b06031
- Wei Yang, Oskar Laaksonen, Heikki Kallio, and Baoru Yang . Proanthocyanidins in Sea Buckthorn (Hippophaë rhamnoides L.) Berries of Different Origins with Special Reference to the Influence of Genetic Background and Growth Location. Journal of Agricultural and Food Chemistry 2016, 64
(6)
, 1274-1282. https://doi.org/10.1021/acs.jafc.5b05718
- Laura Zoratti, Laura Jaakola, Hely Häggman, and Lara Giongo . Anthocyanin Profile in Berries of Wild and Cultivated Vaccinium spp. along Altitudinal Gradients in the Alps. Journal of Agricultural and Food Chemistry 2015, 63
(39)
, 8641-8650. https://doi.org/10.1021/acs.jafc.5b02833
- Mary H. Grace, Debora Esposito, Kriya L. Dunlap, and Mary Ann Lila . Comparative Analysis of Phenolic Content and Profile, Antioxidant Capacity, and Anti-inflammatory Bioactivity in Wild Alaskan and Commercial Vaccinium Berries. Journal of Agricultural and Food Chemistry 2014, 62
(18)
, 4007-4017. https://doi.org/10.1021/jf403810y
- Li-Chen Yang, Rong Li, Jin Tan, and Zi-Tao Jiang . Polyphenolics Composition of the Leaves of Zanthoxylum bungeanum Maxim. Grown in Hebei, China, and Their Radical Scavenging Activities. Journal of Agricultural and Food Chemistry 2013, 61
(8)
, 1772-1778. https://doi.org/10.1021/jf3042825
- Eivind Uleberg, Jens Rohloff, Laura Jaakola, Kajetan Trôst, Olavi Junttila, Hely Häggman, and Inger Martinussen . Effects of Temperature and Photoperiod on Yield and Chemical Composition of Northern and Southern Clones of Bilberry (Vaccinium myrtillus L.). Journal of Agricultural and Food Chemistry 2012, 60
(42)
, 10406-10414. https://doi.org/10.1021/jf302924m
- Anu Lavola, Reijo Karjalainen, and Riitta Julkunen-Tiitto . Bioactive Polyphenols in Leaves, Stems, and Berries of Saskatoon (Amelanchier alnifolia Nutt.) Cultivars. Journal of Agricultural and Food Chemistry 2012, 60
(4)
, 1020-1027. https://doi.org/10.1021/jf204056s
- Verka Gavrilova, Marina Kajdžanoska, Viktor Gjamovski, and Marina Stefova . Separation, Characterization and Quantification of Phenolic Compounds in Blueberries and Red and Black Currants by HPLC−DAD−ESI-MSn. Journal of Agricultural and Food Chemistry 2011, 59
(8)
, 4009-4018. https://doi.org/10.1021/jf104565y
- Yixiang Liu, Xue Song, Yong Han, Feng Zhou, Di Zhang, Baoping Ji, Jimei Hu, Yechun Lv, Shengbao Cai, Ying Wei, Fengyi Gao, and Xiaonan Jia. Identification of Anthocyanin Components of Wild Chinese Blueberries and Amelioration of Light-Induced Retinal Damage in Pigmented Rabbit Using Whole Berries. Journal of Agricultural and Food Chemistry 2011, 59
(1)
, 356-363. https://doi.org/10.1021/jf103852s
- Ali K. J. Koskela, Mikko J. Anttonen, Tuula H. Soininen, Niina M. M. Saviranta, Seppo Auriola, Riitta Julkunen-Tiitto, and Reijo O. Karjalainen . Variation in the Anthocyanin Concentration of Wild Populations of Crowberries (Empetrum nigrum L subsp. hermaphroditum). Journal of Agricultural and Food Chemistry 2010, 58
(23)
, 12286-12291. https://doi.org/10.1021/jf1037695
- Andreas Åkerström, Laura Jaakola, Ulla Bång, and Anders Jäderlund . Effects of Latitude-Related Factors and Geographical Origin on Anthocyanidin Concentrations in Fruits of Vaccinium myrtillus L. (Bilberries). Journal of Agricultural and Food Chemistry 2010, 58
(22)
, 11939-11945. https://doi.org/10.1021/jf102407n
- Ahmed K. Rashwan, Ahmed I. Osman, Naymul Karim, Jianling Mo, Wei Chen. Unveiling the Mechanisms of the Development of Blueberries-Based Functional Foods: An Updated and Comprehensive Review. Food Reviews International 2024, 40
(7)
, 1913-1940. https://doi.org/10.1080/87559129.2023.2245025
- Naser A. Alsharairi. A Review with a Focus on Vaccinium-Berries-Derived Bioactive Compounds for the Treatment of Reproductive Cancers. Plants 2024, 13
(7)
, 1047. https://doi.org/10.3390/plants13071047
- Zuzana Vaneková, Patricia Holloway, Judith M. Rollinger. Vaccinium uliginosum L. (bog bilberry) and the search for its alleged toxicity: a review. Frontiers in Toxicology 2024, 6 https://doi.org/10.3389/ftox.2024.1358840
- Bianca Eugenia Ștefănescu, Sonia Ancuța Socaci, Anca Corina Fărcaș, Silvia Amalia Nemeș, Bernadette Emőke Teleky, Gheorghe Adrian Martău, Lavinia Florina Călinoiu, Laura Mitrea, Floricuța Ranga, Dan Grigoroaea, Dan Cristian Vodnar, Carmen Socaciu. Characterization of the Chemical Composition and Biological Activities of Bog Bilberry (Vaccinium uliginosum L.) Leaf Extracts Obtained via Various Extraction Techniques. Foods 2024, 13
(2)
, 258. https://doi.org/10.3390/foods13020258
- Richard V. Espley, Laura Jaakola. The role of environmental stress in fruit pigmentation. Plant, Cell & Environment 2023, 46
(12)
, 3663-3679. https://doi.org/10.1111/pce.14684
- L. Jaakola, A. Samkumar, K. Karppinen, I. Martinussen. Bluer than blue: regulation of delphinidin branch anthocyanins in
Vaccinium
berries. Acta Horticulturae 2023, 58
(1381)
, 191-198. https://doi.org/10.17660/ActaHortic.2023.1381.26
- Agnieszka Kopystecka, Ilona Kozioł, Dominika Radomska, Krzysztof Bielawski, Anna Bielawska, Monika Wujec. Vaccinium uliginosum and Vaccinium myrtillus—Two Species—One Used as a Functional Food. Nutrients 2023, 15
(19)
, 4119. https://doi.org/10.3390/nu15194119
- Riikka Räisänen, Anja Primetta, Peppi Toukola, Silja Fager, Joanna Ylänen. Biocolourants from onion crop side streams and forest mushroom for regenerated cellulose fibres. Industrial Crops and Products 2023, 198 , 116748. https://doi.org/10.1016/j.indcrop.2023.116748
- D. V. Sokolova, A. E. Solovieva. Characterization of the biochemical composition and antioxidant activity of Spinacia oleracea L. and Spinacia turkestanica Iljin.: a comparative study. Vegetable crops of Russia 2023,
(4)
, 23-29. https://doi.org/10.18619/2072-9146-2023-4-23-29
- M. Amundsen, L. Jaakola, K. Aaby, I. Martinussen, N. Kelanne, S. Tuominen, O. Laaksonen, B. Yang, AL. Hykkerud. Effect of ripening temperature on the chemical composition of lingonberries (Vaccinium vitis-idaea L.) of northern and southern origin. Food Research International 2023, 167 , 112738. https://doi.org/10.1016/j.foodres.2023.112738
- Guorong Fan, Xiaodan Ning, Shangxing Chen, Liang Zhong, Chunce Guo, Yuling Yang, Juan Liu, Ming Tang, Guoxiang Liao, Xuefang Wang, Zongde Wang, Jiawei Wang. Differences in fruit yields and essential oil contents and composition among natural provenances of Litsea cubeba in China and their relationships with main habitat factors. Industrial Crops and Products 2023, 194 , 116285. https://doi.org/10.1016/j.indcrop.2023.116285
- Xuan Wang, Qi Tang, Fumei Chi, Hongdi Liu, Hongjun Zhang, Yang Song. Sucrose non-fermenting1-related protein kinase VcSnRK2.3 promotes anthocyanin biosynthesis in association with VcMYB1 in blueberry. Frontiers in Plant Science 2023, 14 https://doi.org/10.3389/fpls.2023.1018874
- Charles F. Manful, Ahsan Hameed, Raymond H. Thomas. Berries. 2023, 161-217. https://doi.org/10.1016/B978-0-12-823811-0.00004-3
- Yu Wang, Xin Liu, Jia-Zhuo Chen, Xin Tian, Yu-Hang Zheng, Jia Hao, Yu-Jian Xue, Shao-Yu Ding, Cheng-Wen Zong. The variation of total flavonoids, anthocyanins and total phenols in Vaccinium uliginosum fruits in Changbai Mountain of China is closely related to spatial distribution. Journal of Berry Research 2022, 12
(4)
, 463-481. https://doi.org/10.3233/JBR-220025
- Jerome Higbee, Patrick Solverson, Meijun Zhu, Franck Carbonero. The emerging role of dark berry polyphenols in human health and nutrition. Food Frontiers 2022, 3
(1)
, 3-27. https://doi.org/10.1002/fft2.128
- Xingguo Li, Xiaotian Wang, Xue Guo, Dalong Li, Junwei Huo, Zeyuan Yu. Structural and Biochemical Characterization of a Polysaccharide Isolated From
Vaccinium uliginosum
L. Starch - Stärke 2022, 74
(1-2)
https://doi.org/10.1002/star.202100109
- Sorin Ciulca, Gheorghe Roma, Ersilia Alexa, Isidora Radulov, Ileana Cocan, Emilian Madosa, Adriana Ciulca. Variation of Polyphenol Content and Antioxidant Activity in Some Bilberry (Vaccinium myrtillus L.) Populations from Romania. Agronomy 2021, 11
(12)
, 2557. https://doi.org/10.3390/agronomy11122557
- Qi Tang, Fu-Mei Chi, Hong-Di Liu, Hong-Jun Zhang, Yang Song. Single-Molecule Real-Time and Illumina Sequencing to Analyze Transcriptional Regulation of Flavonoid Synthesis in Blueberry. Frontiers in Plant Science 2021, 12 https://doi.org/10.3389/fpls.2021.754325
- Jørgen A. B. Mølmann, Sigridur Dalmannsdottir, Anne Linn Hykkerud, Timo Hytönen, Amos Samkumar, Laura Jaakola. Influence of Arctic light conditions on crop production and quality. Physiologia Plantarum 2021, 172
(4)
, 1931-1940. https://doi.org/10.1111/ppl.13418
- Fabiana Antognoni, Giulia Potente, Stefania Biondi, Roberto Mandrioli, Lorenzo Marincich, Karina B. Ruiz. Free and Conjugated Phenolic Profiles and Antioxidant Activity in Quinoa Seeds and Their Relationship with Genotype and Environment. Plants 2021, 10
(6)
, 1046. https://doi.org/10.3390/plants10061046
- Rosa Tundis, Maria C. Tenuta, Monica R. Loizzo, Marco Bonesi, Federica Finetti, Lorenza Trabalzini, Brigitte Deguin. Vaccinium Species (Ericaceae): From Chemical Composition to Bio-Functional Activities. Applied Sciences 2021, 11
(12)
, 5655. https://doi.org/10.3390/app11125655
- Erika Krüger, Frank Will, Keshav Kumar, Karolina Celejewska, Philippe Chartier, Agnieszka Masny, Daniela Mott, Aurélie Petit, Gianluca Savini, Anita Sønsteby. Influence of Post-Flowering Climate Conditions on Anthocyanin Profile of Strawberry Cultivars Grown from North to South Europe. Applied Sciences 2021, 11
(3)
, 1326. https://doi.org/10.3390/app11031326
- Kyungae Jo, Gi Yeon Bae, Kyoungwon Cho, Sung Sun Park, Hyung Joo Suh, Ki-Bae Hong. An Anthocyanin-Enriched Extract from Vaccinium uliginosum Improves Signs of Skin Aging in UVB-Induced Photodamage. Antioxidants 2020, 9
(9)
, 844. https://doi.org/10.3390/antiox9090844
- Esther Asensio, Daniel Vitales, Iván Pérez, Laia Peralba, Juan Viruel, Celia Montaner, Joan Vallès, Teresa Garnatje, Ester Sales. Phenolic Compounds Content and Genetic Diversity at Population Level across the Natural Distribution Range of Bearberry (Arctostaphylos uva-ursi, Ericaceae) in the Iberian Peninsula. Plants 2020, 9
(9)
, 1250. https://doi.org/10.3390/plants9091250
- Tânia C. S. P. Pires, Cristina Caleja, Celestino Santos-Buelga, Lillian Barros, Isabel C.F.R. Ferreira. Vaccinium myrtillus L. Fruits as a Novel Source of Phenolic Compounds with Health Benefits and Industrial Applications - A Review. Current Pharmaceutical Design 2020, 26
(16)
, 1917-1928. https://doi.org/10.2174/1381612826666200317132507
- Yu Wang, Haobo Yang, Shuai Zhong, Xin Liu, Tong Li, Chengwen Zong. Variations in Sugar and Organic Acid Content of Fruit Harvested from Different Vaccinium uliginosum Populations in the Changbai Mountains of China. Journal of the American Society for Horticultural Science 2019, 144
(6)
, 420-428. https://doi.org/10.21273/JASHS04740-19
- Anna Spinardi, Gabriele Cola, Claudio Sebastiano Gardana, Ilaria Mignani. Variation of Anthocyanin Content and Profile Throughout Fruit Development and Ripening of Highbush Blueberry Cultivars Grown at Two Different Altitudes. Frontiers in Plant Science 2019, 10 https://doi.org/10.3389/fpls.2019.01045
- Yusong Jin, Yunhui Zhang, Dongmei Liu, Dewen Liu, Chunying Zhang, Huijuan Qi, Huiyan Gu, Lei Yang, Zhiqiang Zhou. Efficient Homogenization-Ultrasound-Assisted Extraction of Anthocyanins and Flavonols from Bog Bilberry (Vaccinium uliginosum L.) Marc with Carnosic Acid as an Antioxidant Additive. Molecules 2019, 24
(14)
, 2537. https://doi.org/10.3390/molecules24142537
- Bianca Eugenia Ștefănescu, Katalin Szabo, Andrei Mocan, Gianina Crişan. Phenolic Compounds from Five Ericaceae Species Leaves and Their Related Bioavailability and Health Benefits. Molecules 2019, 24
(11)
, 2046. https://doi.org/10.3390/molecules24112046
- Yang Lin, Yuehua Wang, Bin Li, Hui Tan, Dongnan Li, Li Li, Xuan Liu, Jichen Han, Xianjun Meng. Comparative transcriptome analysis of genes involved in anthocyanin synthesis in blueberry. Plant Physiology and Biochemistry 2018, 127 , 561-572. https://doi.org/10.1016/j.plaphy.2018.04.034
- Zichao Wang, Yuzhen Yan, Tanzeela Nisar, Li Zou, Xi Yang, Pengfei Niu, Lijun Sun, Yurong Guo. Comparison and multivariate statistical analysis of anthocyanin composition in Lycium ruthenicum Murray from different regions to trace geographical origins: The case of China. Food Chemistry 2018, 246 , 233-241. https://doi.org/10.1016/j.foodchem.2017.11.030
- Jasmina Petreska Stanoeva, Marina Stefova, Katerina Baceva Andonovska, Ana Vankova, Trajce Stafilov. Phenolics and mineral content in bilberry and bog bilberry from Macedonia. International Journal of Food Properties 2017, 20
(sup1)
, S863-S883. https://doi.org/10.1080/10942912.2017.1315592
- Andrzej Cendrowski, Iwona Ścibisz, Marek Kieliszek, Joanna Kolniak-Ostek, Marta Mitek. UPLC-PDA-Q/TOF-MS Profile of Polyphenolic Compounds of Liqueurs from Rose Petals (Rosa rugosa). Molecules 2017, 22
(11)
, 1832. https://doi.org/10.3390/molecules22111832
- Anu Lavola, Anneli Salonen, Virpi Virjamo, Riitta Julkunen-Tiitto. Phytochemical variation in the plant-part specific phenols of wild crowberry ( Empetrum hermaphroditum Hagerup) populations. Phytochemistry Letters 2017, 21 , 11-20. https://doi.org/10.1016/j.phytol.2017.05.016
- Cheng-Yong Feng, Wei-Wei Wang, Jian-Fei Ye, Shan-Shan Li, Qian Wu, Dan-Dan Yin, Bing Li, Yan-Jun Xu, Liang-Sheng Wang. Polyphenol profile and antioxidant activity of the fruit and leaf of Vaccinium glaucoalbum from the Tibetan Himalayas. Food Chemistry 2017, 219 , 490-495. https://doi.org/10.1016/j.foodchem.2016.09.083
- Claudia Ancillotti, Lorenzo Ciofi, Daniele Rossini, Ugo Chiuminatto, Jianru Stahl-Zeng, Serena Orlandini, Sandra Furlanetto, Massimo Del Bubba. Liquid chromatographic/electrospray ionization quadrupole/time of flight tandem mass spectrometric study of polyphenolic composition of different Vaccinium berry species and their comparative evaluation. Analytical and Bioanalytical Chemistry 2017, 409
(5)
, 1347-1368. https://doi.org/10.1007/s00216-016-0067-y
- Jihye Yang, Kyunghee Song, Yunhee Chang, Youngmi Lee. Culinary Characteristics of Hwachae in Korean Cookbooks Published in 1600-1940s. Korean Journal of Food & Cookery Science 2016, 32
(6)
, 800-810. https://doi.org/10.9724/kfcs.2016.32.6.800
- Wei-An Chang, Jen-Yu Hung, Shu-Fang Jian, Yi-Shiuan Lin, Cheng-Ying Wu, Ya-Ling Hsu, Po-Lin Kuo. Laricitrin ameliorates lung cancer-mediated dendritic cell suppression by inhibiting signal transducer and activator of transcription 3. Oncotarget 2016, 7
(51)
, 85220-85234. https://doi.org/10.18632/oncotarget.13240
- Oana-Crina Bujor, Carine Le Bourvellec, Irina Volf, Valentin I. Popa, Claire Dufour. Seasonal variations of the phenolic constituents in bilberry ( Vaccinium myrtillus L.) leaves, stems and fruits, and their antioxidant activity. Food Chemistry 2016, 213 , 58-68. https://doi.org/10.1016/j.foodchem.2016.06.042
- Bom-Lee Lee, Jung-Hwan Kang, Hye-Mi Kim, Se-Hee Jeong, Dae-Sik Jang, Young-Pyo Jang, Se-Young Choung. Polyphenol-enriched Vaccinium uliginosum L. fractions reduce retinal damage induced by blue light in A2E-laden ARPE19 cell cultures and mice. Nutrition Research 2016, 36
(12)
, 1402-1414. https://doi.org/10.1016/j.nutres.2016.11.008
- Claudia Ancillotti, Lorenzo Ciofi, Daniele Pucci, Eva Sagona, Edgardo Giordani, Stefano Biricolti, Massimo Gori, William Antonio Petrucci, Fabio Giardi, Riccardo Bartoletti, Ugo Chiuminatto, Serena Orlandini, Stefano Mosti, Massimo Del Bubba. Polyphenolic profiles and antioxidant and antiradical activity of Italian berries from Vaccinium myrtillus L. and Vaccinium uliginosum L. subsp. gaultherioides (Bigelow) S.B. Young. Food Chemistry 2016, 204 , 176-184. https://doi.org/10.1016/j.foodchem.2016.02.106
- Xueying Ma, Oskar Laaksonen, Jie Zheng, Wei Yang, Martin Trépanier, Heikki Kallio, Baoru Yang. Flavonol glycosides in berries of two major subspecies of sea buckthorn (Hippophaë rhamnoides L.) and influence of growth sites. Food Chemistry 2016, 200 , 189-198. https://doi.org/10.1016/j.foodchem.2016.01.036
- Nesrin Colak, Hülya Torun, Jiri Gruz, Miroslav Strnad, Isidro Hermosín-Gutiérrez, Sema Hayirlioglu-Ayaz, Faik Ahmet Ayaz. Bog bilberry phenolics, antioxidant capacity and nutrient profile. Food Chemistry 2016, 201 , 339-349. https://doi.org/10.1016/j.foodchem.2016.01.062
- Shang Su, Li-Jin Wang, Cheng-Yong Feng, Yang Liu, Chong-Hui Li, Hui Du, Zhong-Qiu Tang, Yan-Jun Xu, Liang-Sheng Wang. Fingerprints of anthocyanins and flavonols of Vaccinium uliginosum berries from different geographical origins in the Greater Khingan Mountains and their antioxidant capacities. Food Control 2016, 64 , 218-225. https://doi.org/10.1016/j.foodcont.2016.01.006
- Katja Karppinen, Laura Zoratti, Nga Nguyenquynh, Hely Häggman, Laura Jaakola. On the Developmental and Environmental Regulation of Secondary Metabolism in Vaccinium spp. Berries. Frontiers in Plant Science 2016, 7 https://doi.org/10.3389/fpls.2016.00655
- Niranjan Koirala, Nguyen Huy Thuan, Gopal Prasad Ghimire, Duong Van Thang, Jae Kyung Sohng. Methylation of flavonoids: Chemical structures, bioactivities, progress and perspectives for biotechnological production. Enzyme and Microbial Technology 2016, 86 , 103-116. https://doi.org/10.1016/j.enzmictec.2016.02.003
- Anne Linn Hykkerud Steindal, Tor J Johansen, Gunnar B Bengtsson, Sidsel F Hagen, Jørgen AB Mølmann. Impact of pre‐harvest light spectral properties on health‐ and sensory‐related compounds in broccoli florets. Journal of the Science of Food and Agriculture 2016, 96
(6)
, 1974-1981. https://doi.org/10.1002/jsfa.7307
- Dongnan Li, Xianjun Meng, Bin Li. Profiling of anthocyanins from blueberries produced in China using HPLC-DAD-MS and exploratory analysis by principal component analysis. Journal of Food Composition and Analysis 2016, 47 , 1-7. https://doi.org/10.1016/j.jfca.2015.09.005
- Shu-Xun Liu, Hang-Yu Yang, Si-Yu Li, Jia-Yue Zhang, Teng Li, Bao-Qing Zhu, Bo-Lin Zhang. Polyphenolic Compositions and Chromatic Characteristics of Bog Bilberry Syrup Wines. Molecules 2015, 20
(11)
, 19865-19877. https://doi.org/10.3390/molecules201119662
- José C. del Valle, Ma L. Buide, Inés Casimiro-Soriguer, Justen B. Whittall, Eduardo Narbona. On flavonoid accumulation in different plant parts: variation patterns among individuals and populations in the shore campion (Silene littorea). Frontiers in Plant Science 2015, 6 https://doi.org/10.3389/fpls.2015.00939
- Anja K. Primetta, Katja Karppinen, Kaisu R. Riihinen, Laura Jaakola. Metabolic and molecular analyses of white mutant Vaccinium berries show down-regulation of MYBPA1-type R2R3 MYB regulatory factor. Planta 2015, 242
(3)
, 631-643. https://doi.org/10.1007/s00425-015-2363-8
- Suresh Govindaraghavan. Pharmacopeial HPLC identification methods are not sufficient to detect adulterations in commercial bilberry (Vaccinium myrtillus) extracts. Anthocyanin profile provides additional clues. Fitoterapia 2014, 99 , 124-138. https://doi.org/10.1016/j.fitote.2014.09.007
- Laura Zoratti, Katja Karppinen, Ana Luengo Escobar, Hely Häggman, Laura Jaakola. Light-controlled flavonoid biosynthesis in fruits. Frontiers in Plant Science 2014, 5 https://doi.org/10.3389/fpls.2014.00534
- Li-Jin Wang, Shang Su, Jie Wu, Hui Du, Shan-Shan Li, Jun-Wei Huo, Yue Zhang, Liang-Sheng Wang. Variation of anthocyanins and flavonols in Vaccinium uliginosum berry in Lesser Khingan Mountains and its antioxidant activity. Food Chemistry 2014, 160 , 357-364. https://doi.org/10.1016/j.foodchem.2014.03.081
- Yixiang Liu, Di Zhang, Yongpei Wu, Dan Wang, Ying Wei, Jiulin Wu, Baoping Ji. Stability and absorption of anthocyanins from blueberries subjected to a simulated digestion process. International Journal of Food Sciences and Nutrition 2014, 65
(4)
, 440-448. https://doi.org/10.3109/09637486.2013.869798
- Monica Jordheim. Basic Anthocyanin Chemistry and Dietary Sources. 2013, 13-90. https://doi.org/10.1201/b15554-3
- Timothy D. Miles, Christine Vandervoort, Muraleedharan G. Nair, Annemiek C. Schilder. Characterization and biological activity of flavonoids from ripe fruit of an anthracnose-resistant blueberry cultivar. Physiological and Molecular Plant Pathology 2013, 83 , 8-16. https://doi.org/10.1016/j.pmpp.2013.02.004
- Anja K. Primetta, Laura Jaakola, Faik A. Ayaz, Huseyin Inceer, Kaisu R. Riihinen. Anthocyanin fingerprinting for authenticity studies of bilberry (Vaccinium myrtillus L.). Food Control 2013, 30
(2)
, 662-667. https://doi.org/10.1016/j.foodcont.2012.09.009
- Claudia Drossard, Katja Bolzenius, Clemens Kunz, Mathilde Kersting. Anthocyanins in the diet of children and adolescents: intake, sources and trends. European Journal of Nutrition 2013, 52
(2)
, 667-676. https://doi.org/10.1007/s00394-012-0371-z
- Kajetan Trošt, Eivind Uleberg, Inger Martinussen. Levels of individual anthocyanins and hydroxycinnamic derivates in selected clones of cloudberry (
Rubus chamaemorus
). Acta Agriculturae Scandinavica, Section B - Soil & Plant Science 2013, 63
(2)
, 147-152. https://doi.org/10.1080/09064710.2012.733726
- Kanika Patel, Achint Jain, Dinesh K. Patel. Medicinal significance, pharmacological activities, and analytical aspects of anthocyanidins ‘delphinidin’: A concise report. Journal of Acute Disease 2013, 2
(3)
, 169-178. https://doi.org/10.1016/S2221-6189(13)60123-7
- Hyun Kyung Kil, You Mi Song, KoI Chun. The Efficacy of
Vaccinium Uliginosum
for Early Age-Related Macula Degeneration. Journal of the Korean Ophthalmological Society 2013, 54
(8)
, 1255. https://doi.org/10.3341/jkos.2013.54.8.1255
- Raja S Payyavula, Duroy A Navarre, Joseph C Kuhl, Alberto Pantoja, Syamkumar S Pillai. Differential effects of environment on potato phenylpropanoid and carotenoid expression. BMC Plant Biology 2012, 12
(1)
https://doi.org/10.1186/1471-2229-12-39
- Urska Vrhovsek, Domenico Masuero, Luisa Palmieri, Fulvio Mattivi. Identification and quantification of flavonol glycosides in cultivated blueberry cultivars. Journal of Food Composition and Analysis 2012, 25
(1)
, 9-16. https://doi.org/10.1016/j.jfca.2011.04.015
- Claudia Drossard, Ute Alexy, Katja Bolzenius, Clemens Kunz, Mathilde Kersting. Anthocyanins in the diet of infants and toddlers: intake, sources and trends. European Journal of Nutrition 2011, 50
(8)
, 705-711. https://doi.org/10.1007/s00394-011-0184-5
- Christopher M. Wallis, Dezene P. W. Huber, Kathy J. Lewis. Ecosystem, Location, and Climate Effects on Foliar Secondary Metabolites of Lodgepole Pine Populations from Central British Columbia. Journal of Chemical Ecology 2011, 37
(6)
, 607-621. https://doi.org/10.1007/s10886-011-9958-8
- Anja K. Lätti, Kaisu R. Riihinen, Laura Jaakola. Phenolic compounds in berries and flowers of a natural hybrid between bilberry and lingonberry (Vaccinium×intermedium Ruthe). Phytochemistry 2011, 72
(8)
, 810-815. https://doi.org/10.1016/j.phytochem.2011.02.015
- LAURA JAAKOLA, ANJA HOHTOLA. Effect of latitude on flavonoid biosynthesis in plants. Plant, Cell & Environment 2010, 33
(8)
, 1239-1247. https://doi.org/10.1111/j.1365-3040.2010.02154.x
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