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Novel inhibitors of prolyl 4-hydroxylase

Cite this: J. Med. Chem. 1992, 35, 5, 800–804
Publication Date (Print):March 1, 1992
https://doi.org/10.1021/jm00083a001
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    This article is cited by 18 publications.

    1. James D. Vasta, Ronald T. Raines. Collagen Prolyl 4-Hydroxylase as a Therapeutic Target. Journal of Medicinal Chemistry 2018, 61 (23) , 10403-10411. https://doi.org/10.1021/acs.jmedchem.8b00822
    2. Fei Xu, Behnam Nazari, Kyuho Moon, Leah B. Bushin, and Mohammad R. Seyedsayamdost . Discovery of a Cryptic Antifungal Compound from Streptomyces albus J1074 Using High-Throughput Elicitor Screens. Journal of the American Chemical Society 2017, 139 (27) , 9203-9212. https://doi.org/10.1021/jacs.7b02716
    3. James D. Vasta, Kristen A. Andersen, Kathryn M. Deck, Christopher P. Nizzi, Richard S. Eisenstein, and Ronald T. Raines . Selective Inhibition of Collagen Prolyl 4-Hydroxylase in Human Cells. ACS Chemical Biology 2016, 11 (1) , 193-199. https://doi.org/10.1021/acschembio.5b00749
    4. Mario Thevis, Maxie Kohler, Nils Schlörer, Wilhelm Schänzer. Gas phase reaction of substituted isoquinolines to carboxylic acids in ion trap and triple quadrupole mass spectrometers after electrospray ionization and collision-induced dissociation. Journal of the American Society for Mass Spectrometry 2008, 19 (1) , 151-158. https://doi.org/10.1016/j.jasms.2007.11.003
    5. Thomas P. Corner, Ryan Z. R. Teo, Yue Wu, Eidarus Salah, Yu Nakashima, Giorgia Fiorini, Anthony Tumber, Amelia Brasnett, James P. Holt-Martyn, William D. Figg, Xiaojin Zhang, Lennart Brewitz, Christopher J. Schofield. Structure-guided optimisation of N -hydroxythiazole-derived inhibitors of factor inhibiting hypoxia-inducible factor-α. Chemical Science 2023, 14 (43) , 12098-12120. https://doi.org/10.1039/D3SC04253G
    6. Denis N. Tomilin, Lyubov N. Sobenina, Ivan V. Saliy, Igor A. Ushakov, Aleksandra M. Belogolova, Boris A. Trofimov. Substituted pyrrolyl-cyanopyridines on the platform of acylethynylpyrroles via their 1 : 2 annulation with acetonitrile under the action of lithium metal. New Journal of Chemistry 2022, 46 (27) , 13149-13155. https://doi.org/10.1039/D2NJ02011D
    7. Marialucia Gallorini, Simone Carradori. Understanding collagen interactions and their targeted regulation by novel drugs. Expert Opinion on Drug Discovery 2021, 16 (11) , 1239-1260. https://doi.org/10.1080/17460441.2021.1933426
    8. Robert J. Mishur, Maruf Khan, Erin Munkácsy, Lokendra Sharma, Alex Bokov, Haley Beam, Oxana Radetskaya, Megan Borror, Rebecca Lane, Yidong Bai, Shane L. Rea. Mitochondrial metabolites extend lifespan. Aging Cell 2016, 15 (2) , 336-348. https://doi.org/10.1111/acel.12439
    9. James D. Vasta, Ronald T. Raines. Selective inhibition of prolyl 4-hydroxylases by bipyridinedicarboxylates. Bioorganic & Medicinal Chemistry 2015, 23 (13) , 3081-3090. https://doi.org/10.1016/j.bmc.2015.05.003
    10. P. Barczyński, A. Komasa, A. Katrusiak, Z. Dega-Szafran, Ł. Nowaczyk, M. Ratajczak-Sitarz, M. Szafran. Spectroscopic and structural investigation of 2,5-dicarboxy-1-methylpyridinium inner salt. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2014, 121 , 586-595. https://doi.org/10.1016/j.saa.2013.10.123
    11. Nathan R. Rose, Michael A. McDonough, Oliver N. F. King, Akane Kawamura, Christopher J. Schofield. Inhibition of 2-oxoglutarate dependent oxygenases. Chemical Society Reviews 2011, 40 (8) , 4364. https://doi.org/10.1039/c0cs00203h
    12. . Novel Inhibitors of Prolyl 4-Hydroxylase; Solid-phase Synthesis of 2,2-Dimethyl-3,4-Dialkoxy-Substituted 6-Aminobenzopyran Derivatives. Bulletin of the Korean Chemical Society 2006, 909-917. https://doi.org/10.5012/bkcs.2006.27.6.909
    13. Robert Rucker, Jerold Last, Ana Samimi. Prolyl 4-Hydroxylase. 2002https://doi.org/10.1201/9780203910450.ch35
    14. John A Morgan, Jacqueline V Shanks. Inhibitor studies of tabersonine metabolism in C. roseus hairy roots. Phytochemistry 1999, 51 (1) , 61-68. https://doi.org/10.1016/S0031-9422(98)00585-8
    15. Kari I. Kivirikko, Taina Pihlajaniemi. Collagen Hydroxylases and the Protein Disulfide Isomerase Subunit of Prolyl 4‐Hydroxylases. 1998, 325-398. https://doi.org/10.1002/9780470123188.ch9
    16. Ari M.P. Koskinen, Jörg Schwerdtfeger, Michael Edmonds. A simple route to 4-substituted-3,4-didehydroprolines. Mechanistic probes for the inhibition of prolyl-4-hydroxylase. Tetrahedron Letters 1997, 38 (30) , 5399-5402. https://doi.org/10.1016/S0040-4039(97)01182-9
    17. V. Srinivasan, V. Ciddi, V. Bringi, M. L. Shuler. Metabolic Inhibitors, Elicitors, and Precursors as Tools for Probing Yield Limitation in Taxane Production by Taxus chinensis Cell Cultures. Biotechnology Progress 1996, 12 (4) , 457-465. https://doi.org/10.1021/bp9600344
    18. RI Dowell, NH Hales, H Tucker. Novel inhibitors of prolyl 4-hydroxylase. Part 4 pyridine-2-carboxylic acid analogues with alternative 2-substituents. European Journal of Medicinal Chemistry 1993, 28 (6) , 513-516. https://doi.org/10.1016/0223-5234(93)90019-B

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