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2-Alkynyl derivatives of adenosine and adenosine-5'-N-ethyluronamide as selective agonists at A2 adenosine receptors

Cite this: J. Med. Chem. 1992, 35, 13, 2363–2368
Publication Date (Print):June 1, 1992
https://doi.org/10.1021/jm00091a003
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    Cited By

    This article is cited by 74 publications.

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    2. Rosaria Volpini, Michela Buccioni, Diego Dal Ben, Catia Lambertucci, Carmen Lammi, Gabriella Marucci, Anna T. Ramadori, Karl-Norbert Klotz and Gloria Cristalli . Synthesis and Biological Evaluation of 2-Alkynyl-N6-methyl-5′-N-methylcarboxamidoadenosine Derivatives as Potent and Highly Selective Agonists for the Human Adenosine A3 Receptor. Journal of Medicinal Chemistry 2009, 52 (23) , 7897-7900. https://doi.org/10.1021/jm900754g
    3. Thomas Borrmann, Aliaa Abdelrahman, Rosaria Volpini, Catia Lambertucci, Edgars Alksnis, Simone Gorzalka, Melanie Knospe, Anke C. Schiedel, Gloria Cristalli and Christa E. Müller . Structure−Activity Relationships of Adenine and Deazaadenine Derivatives as Ligands for Adenine Receptors, a New Purinergic Receptor Family. Journal of Medicinal Chemistry 2009, 52 (19) , 5974-5989. https://doi.org/10.1021/jm9006356
    4. Rosaria Volpini,, Diego Dal Ben,, Catia Lambertucci,, Sara Taffi,, Sauro Vittori,, Karl-Norbert Klotz, and, Gloria Cristalli. N6-Methoxy-2-alkynyladenosine Derivatives as Highly Potent and Selective Ligands at the Human A3 Adenosine Receptor. Journal of Medicinal Chemistry 2007, 50 (6) , 1222-1230. https://doi.org/10.1021/jm060963u
    5. M. Pilar Bosch,, Francisco Campos,, Itziar Niubó,, Gloria Rosell,, J. Luis Díaz,, J. Brea,, M. Isabel Loza, and, Angel Guerrero. Synthesis and Biological Activity of New Potential Agonists for the Human Adenosine A2A Receptor. Journal of Medicinal Chemistry 2004, 47 (16) , 4041-4053. https://doi.org/10.1021/jm031143+
    6. Rosaria Volpini,, Stefano Costanzi,, Catia Lambertucci,, Sara Taffi,, Sauro Vittori,, Karl-Norbert Klotz, and, Gloria Cristalli. N6-Alkyl-2-alkynyl Derivatives of Adenosine as Potent and Selective Agonists at the Human Adenosine A3 Receptor and a Starting Point for Searching A2B Ligands. Journal of Medicinal Chemistry 2002, 45 (15) , 3271-3279. https://doi.org/10.1021/jm0109762
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    11. Pier Giovanni Baraldi,, Barbara Cacciari,, Giampiero Spalluto,, Xiao-duo Ji,, Mark E. Olah,, Gary Stiles,, Silvio Dionisotti,, Cristina Zocchi,, Ennio Ongini, and, Kenneth A. Jacobson. Novel N6-(Substituted-phenylcarbamoyl)adenosine-5‘-uronamides as Potent Agonists for A3 Adenosine Receptors. Journal of Medicinal Chemistry 1996, 39 (3) , 802-806. https://doi.org/10.1021/jm950518r
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