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Immobilized glucuronosyltransferase for the synthesis of conjugates

Cite this: J. Med. Chem. 1976, 19, 2, 296–299
Publication Date (Print):February 1, 1976
https://doi.org/10.1021/jm00224a018
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    Cited By

    This article is cited by 32 publications.

    1. Howard Horng, Hilde Spahn-Langguth, Leslie Z. Benet. Mechanistic Role of Acyl Glucuronides. 2013, 35-70. https://doi.org/10.1016/B978-0-12-387817-5.00003-0
    2. P L Williams, A C Moffat. Identification in human urine of Δ9-tetrahydrocannabinol-11-oic acid glucuronide: a tetrahydrocannabinol metabolite. Journal of Pharmacy and Pharmacology 2011, 32 (1) , 445-448. https://doi.org/10.1111/j.2042-7158.1980.tb12966.x
    3. Yousuke Kashima, Takashi Kitade, Yuuko Kashima, Yoshito Okabayashi. Development of an Automated Synthesis System for Preparation of Glucuronides Using a Solid-Phase Extraction Column Loaded with Microsomes. Chemical and Pharmaceutical Bulletin 2010, 58 (3) , 354-358. https://doi.org/10.1248/cpb.58.354
    4. Hee Seung Kim, Irving W. Wainer. The covalent immobilization of microsomal uridine diphospho-glucuronosyltransferase (UDPGT): Initial synthesis and characterization of an UDPGT immobilized enzyme reactor for the on-line study of glucuronidation. Journal of Chromatography B 2005, 823 (2) , 158-166. https://doi.org/10.1016/j.jchromb.2005.06.030
    5. Matthias Kittelmann, Urs Rheinegger, Aude Espigat, Lukas Oberer, Reiner Aichholz, Eric Francotte, Oreste Ghisalba. Preparative Enzymatic Synthesis of the Acylglucuronide of Mycophenolic Acid. Advanced Synthesis & Catalysis 2003, 345 (6-7) , 825-829. https://doi.org/10.1002/adsc.200303044
    6. Hiroshi Kamimori, Yoshihisa Ozaki, Yoshito Okabayashi, Kyoji Ueno, Shigeru Narita. Synthesis of acylglucuronides of drugs using immobilized dog liver microsomes octadecylsilica particles coated with phospholipid. Analytical Biochemistry 2003, 317 (1) , 99-106. https://doi.org/10.1016/S0003-2697(03)00111-8
    7. Kumiko Sakai-Kato, Masaru Kato, Toshimasa Toyo’oka. On-line drug–metabolism system using microsomes encapsulated in a capillary by the sol–gel method and integrated into capillary electrophoresis. Analytical Biochemistry 2002, 308 (2) , 278-284. https://doi.org/10.1016/S0003-2697(02)00231-2
    8. Alexander M. Klibanov, Gennady P. Samokhin, Karel Martinek, Ilya V. Berezin. A new approach to preparative enzymatic synthesis. Biotechnology and Bioengineering 2000, 67 (6) , 737-747. https://doi.org/10.1002/(SICI)1097-0290(20000320)67:6<737::AID-BIT12>3.0.CO;2-2
    9. Marika Pasternyk Di Marco, Guy Felix, Vincent Descorps, Murray P Ducharme, Irving W Wainer. On-line deconjugation of glucuronides using an immobilized enzyme reactor based upon β-glucuronidase. Journal of Chromatography B: Biomedical Sciences and Applications 1998, 715 (2) , 379-386. https://doi.org/10.1016/S0378-4347(98)00229-1
    10. Andrew V. Stachulski, Gareth V. Jenkins. The synthesis of O-glucuronides. Natural Product Reports 1998, 15 (2) , 173. https://doi.org/10.1039/a815173y
    11. Hélène Juteau, Yves Gareau, Marc Labelle. A convenient synthesis of β-acyl glucuronides. Tetrahedron Letters 1997, 38 (9) , 1481-1484. https://doi.org/10.1016/S0040-4039(97)00135-4
    12. Scott D. Studenberg, Debra L. Price‐Raybuck, Steve E. Unger, John Shockcor, Kim L.R. Brouwer. Characterization ofp‐Hydroxyphenobarbital Glucuronide Generated from lmmobilized Rat Hepatic UDP‐Glucuronosyltransferase. Journal of Pharmaceutical Sciences 1995, 84 (9) , 1134-1136. https://doi.org/10.1002/jps.2600840918
    13. H. He, G. McKay, K. K. Midha. Phase I and II metabolites of benztropine in rat urine and bile. Xenobiotica 1995, 25 (8) , 857-872. https://doi.org/10.3109/00498259509061899
    14. T. Alebić-Kolbah, I. W. Wainer. Microsomal immobilized-enzyme-reactor for on-line production of glucuronides in a HPLC column. Chromatographia 1993, 37 (11-12) , 608-612. https://doi.org/10.1007/BF02274110
    15. Ron A.H.J. Gilissen, John H.N. Meerman, Gerard J. Mulder. Immobilization of solubilized UDP-glucuronosyltransferase from rat liver microsomes to Sepharose 4B. Biochemical Pharmacology 1992, 43 (12) , 2661-2663. https://doi.org/10.1016/0006-2952(92)90157-E
    16. Jan Vanggaard Andersen, Steen Honoré Hansen. Simultaneous quantitative determination of naproxen, its metabolite 6-O-desmethylnaproxen and their five conjugates in plasma and urine samples by high-performance liquid chromatography on dynamically modified silica. Journal of Chromatography B: Biomedical Sciences and Applications 1992, 577 (2) , 325-333. https://doi.org/10.1016/0378-4347(92)80254-N
    17. Hildegard Spahn Langguth, Leslie Z. Benet. Acyl Glucuronides Revisited: Is the Glucuronidation Proces a Toxification as Well as a Detoxification Mechanism?. Drug Metabolism Reviews 1992, 24 (1) , 5-47. https://doi.org/10.3109/03602539208996289
    18. C. J. C. Jackson, J. W. Hubbard, K. K. Midha. Biosynthesis and characterization of glucuronide metabolites of fluphenazine: 7-hydroxyfluphenazine glucuronide and fluphenazine glucuronide. Xenobiotica 1991, 21 (3) , 383-393. https://doi.org/10.3109/00498259109039478
    19. Raymond McCague, Iris B. Parr, Guy Leclercq, On-Tai Leung, Michael Jarman. Metabolism of tamoxifen by isolated rat hepatocytes. Biochemical Pharmacology 1990, 39 (9) , 1459-1465. https://doi.org/10.1016/0006-2952(90)90427-M
    20. F. Tegtmeier, K. Belsner, G. Brunner. Enzymatic synthesis of glucuronides using lipophilic hollow fiber membranes. Bioprocess Engineering 1988, 3 (1) , 43-47. https://doi.org/10.1007/BF00372859
    21. Richard B. van Breemen, Catherine C. Fenselau, Deanne M. Dulik. Activated Phase II Metabolites: Comparison of Alkylation by 1-0-Acyl Glucuronides and Acyl Sulfates. 1986, 423-429. https://doi.org/10.1007/978-1-4684-5134-4_41
    22. Lemuel B. Wingard. Immobilized drugs and enzymes in biochemical pharmacology. Biochemical Pharmacology 1983, 32 (18) , 2647-2652. https://doi.org/10.1016/0006-2952(83)90070-9
    23. G. Brunner. Advances in the Development of Immobilized Enzymes for Future Extracorporeal Liver Support. 1981, 230-235. https://doi.org/10.1007/978-3-642-96629-3_36
    24. Leslie P. Johnson, Catherine Fenselau. Physico-chemical characterization of anomeric d-glucopyranosiduronic acid conjugates. Carbohydrate Research 1979, 73 (1) , 255-259. https://doi.org/10.1016/S0008-6215(00)85495-6
    25. Samir S. Sofer, Robert A. Wills, Bernard J. Van Wie. A Model Enzymic Extracorporeal Detoxification System. Artificial Organs 1979, 3 (2) , 147-152. https://doi.org/10.1111/j.1525-1594.1979.tb01029.x
    26. S.S. Sofer. Hepatic microsomal enzymes: Potential applications. Enzyme and Microbial Technology 1979, 1 (1) , 3-8. https://doi.org/10.1016/0141-0229(79)90003-6
    27. Karel Martinek, I. V. Berezin. General principles of enzyme stabilization. Journal of Solid-Phase Biochemistry 1977, 2 (4) https://doi.org/10.1007/BF02991328
    28. Catherine Fenselau, Sharon Pallante, Robert P Batzinger, Walter R. Benson, Robert P. Barron, Eric B. Sheinin, Millard Maienthal. Mandelonitrile β-Glucuronide: Synthesis and Characterization. Science 1977, 198 (4317) , 625-627. https://doi.org/10.1126/science.335509
    29. Alexander M. Klibanov, Gennady P. Samokhin, Karel Martinek, Ilya. V. Berezin. A new approach to preparative enzymatic synthesis. Biotechnology and Bioengineering 1977, 19 (9) , 1351-1361. https://doi.org/10.1002/bit.260190908
    30. Michael A. Lyle, Sharon Pallante, Ken Head, Catherine Fenselau. Synthesis and characterization of glucuronides of cannabinol, cannabidiol, Δ9-tetrahydrocannabinol and Δ8-tetrahydrocannabinol. Biological Mass Spectrometry 1977, 4 (3) , 190-196. https://doi.org/10.1002/bms.1200040313
    31. William Cohen, William H. Baricos, Peter R. Kastl, Robert P. Chambers. Membrane-Immobilized Liver Microsome Drug Detoxifier. 1977, 319-328. https://doi.org/10.1007/978-1-4684-2610-6_21
    32. S. S. Sofer. Immobilized hepatic microsomes for the synthesis of glucuronides. Journal of Solid-Phase Biochemistry 1976, 1 (3) , 237-240. https://doi.org/10.1007/BF02991021

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