Pyrazine Diuretics. II. N-Amidino-3-amino-5-substituted 6-Halopyrazinecarboxamides

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67. Michio Kuwahara, Sei Sasaki, Shinichi Uchida, Edward J. Cragoe, Fumiaki Marumo. Different development of apical and basolateral Na-H exchangers in LLC-PK1 renal epithelial cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1994, 1220 (2) , 132-138. https://doi.org/10.1016/0167-4889(94)90128-7
68. Mark C. Alliegro, Mary Anne Alliegro, Edward J. Cragoe, Bert M. Glaser. Amiloride inhibition of angiogenesis in vitro. Journal of Experimental Zoology 1993, 267 (3) , 245-252. https://doi.org/10.1002/jez.1402670302
69. Nelia A. Tobey, Sridhar P. Reddy, Temitope O. Keku, Edward J. Cragoe, Roy C. Orlando. Mechanisms of HCI-Induced lowering of intracellular pH in rabbit esophageal epithelial cells. Gastroenterology 1993, 105 (4) , 1035-1044. https://doi.org/10.1016/0016-5085(93)90946-A
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71. Atsuko Ogawa, Yoshihide Ishikawa, Shigeru Sasakawa. Na+/H+ exchange activity induced by thrombin is not inhibited by protein kinase inhibitors, staurosporine, K-252a, H-7 and sphingosine, in human platelets. Thrombosis Research 1993, 70 (2) , 139-149. https://doi.org/10.1016/0049-3848(93)90155-H
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73. Robert S. Haworth, Edward J. Cragoe, Larry Fliegel. Amiloride and 5-(N-ethyl-N-isopropyl) amiloride inhibit medium acidification and glucose metabolism by the fission yeast Schizosaccharomyces pombe. Biochimica et Biophysica Acta (BBA) - Biomembranes 1993, 1145 (2) , 266-272. https://doi.org/10.1016/0005-2736(93)90298-E
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77. Branka Horvat, Shahram Taheri, Aida Salihagić. Tumour cell proliferation is abolished by inhibitors of and exchange. European Journal of Cancer 1993, 29 (1) , 132-137. https://doi.org/10.1016/0959-8049(93)90591-3
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80. A M Kahn, M Bishara, E J Cragoe, J C Allen, C L Seidel, S S Navran, R G O'Neil, N A McCarty, H Shelat. Effects of serotonin on intracellular pH and contraction in vascular smooth muscle.. Circulation Research 1992, 71 (6) , 1294-1304. https://doi.org/10.1161/01.RES.71.6.1294
81. T Nakanishi, H Gu, M Seguchi, E J Cragoe, K Momma. HCO3(-)-dependent intracellular pH regulation in the premature myocardium.. Circulation Research 1992, 71 (6) , 1314-1323. https://doi.org/10.1161/01.RES.71.6.1314
82. M.W Musch, C Bookstein, D.L Arvans, E.J Cragoe, M.C Rao, E.B Chang. Characterization of chicken intestinal brush border membrane Ns/H exchange. Comparative Biochemistry and Physiology Part A: Physiology 1992, 103 (3) , 439-444. https://doi.org/10.1016/0300-9629(92)90269-V
83. Mary Anne Alliegro, Kimberly D. Dyer, Edward J. Cragoe, Bert M. Glaser, Mark C. Alliegro. High-performance liquid chromatographic method for quantitating plasma levels of amiloride and its analogues. Journal of Chromatography B: Biomedical Sciences and Applications 1992, 582 (1-2) , 217-223. https://doi.org/10.1016/0378-4347(92)80322-H
84. J.W. Armstrong, E.J. Cragoe, J.R. Bourke, G.J. Huxham, S.W. Manley. Chloride conductance of apical membrane in cultured porcine thyroid cells activated by cyclic AMP. Molecular and Cellular Endocrinology 1992, 88 (1-3) , 105-110. https://doi.org/10.1016/0303-7207(92)90014-W
85. Guo H. Zhang, Edward J. Cragoe, James E. Melvin. Regulation of cytoplasmic pH in rat sublingual mucous acini at rest and during muscarinic stimulation. The Journal of Membrane Biology 1992, 129 (3) , 311-321. https://doi.org/10.1007/BF00232912
86. Nelia A. Tobey, Sridhar P. Reddy, Temitope O. Keku, Edward J. Cragoe, Roy C. Orlando. Studies of pHi in rabbit esophageal basal and squamous epithelial cells in culture. Gastroenterology 1992, 103 (3) , 830-839. https://doi.org/10.1016/0016-5085(92)90014-P
87. Mette Ree Holthe, Odd Brørs, Edward J. Cragoe, Terje Veel, Morten Ræder. Determination of active 5-(N,N-hexamethylene)amiloride in pig plasma. Journal of Chromatography B: Biomedical Sciences and Applications 1992, 579 (2) , 376-381. https://doi.org/10.1016/0378-4347(92)80408-I
88. G Vairo, B.G. Cocks, E J Cragoe, J.A. Hamilton. Selective suppression of growth factor-induced cell cycle gene expression by Na+/H+ antiport inhibitors.. Journal of Biological Chemistry 1992, 267 (27) , 19043-19046. https://doi.org/10.1016/S0021-9258(18)41736-X
89. N. Andreeva, B. Khodorov, E. Stelmashook, S. Sokolova, E. Cragoe, I. Victorov. 5-(N-ethyl-N-isopropyl)amiloride and mild acidosis protect cultured cerebellar granule cells against glutamate-induced delayed neuronal death. Neuroscience 1992, 49 (1) , 175-181. https://doi.org/10.1016/0306-4522(92)90085-G
90. Willie R. Ross, William S. Bertrand, Aubrey R. Morrison. Identification of a processed protein related to the human chaperonins (hsp 60) protein in mammalian kidney. Biochemical and Biophysical Research Communications 1992, 185 (2) , 683-687. https://doi.org/10.1016/0006-291X(92)91679-K
91. Takenori Miyamoto, Diego Restrepo, Edward J. Cragoe, John H. Teeter. IP3-and cAMP-induced responses in isolated olfactory receptor neurons from the channel catfish. The Journal of Membrane Biology 1992, 127 (3) , 173-183. https://doi.org/10.1007/BF00231505
92. D Rajotte, P Haddad, A Haman, E J Cragoe, T Hoang. Role of protein kinase C and the Na+/H+ antiporter in suppression of apoptosis by granulocyte macrophage colony-stimulating factor and interleukin-3.. Journal of Biological Chemistry 1992, 267 (14) , 9980-9987. https://doi.org/10.1016/S0021-9258(19)50188-0
93. Salvador Viniegra, Edward J. Cragoe, Carlos A. Rabito. Heterogeneity of the Na+H+ antiport systems in renal cells. Biochimica et Biophysica Acta (BBA) - Biomembranes 1992, 1106 (1) , 99-109. https://doi.org/10.1016/0005-2736(92)90227-D
94. Lucio Annunziato, Maurizio Taglialatela, Lorella M.T. Canzoniero, Alessandro Fatatis, Gianfranco Di Rienzo. The Na+-Ca++ exchanger in central nerve endings: The relationship between its pharmacological blockade and dopamine release from tuberoinfundibular hypothalamic neurons. Neurochemistry International 1992, 20 , 95-99. https://doi.org/10.1016/0197-0186(92)90218-G
95. Paolo Parenti, Patrizia Ferrari, Mara Ferrandi, Giorgio M. Hanozet, Giuseppe Bianchi. Effect of amiloride analogues on sodium transport in renal brush border membrane vesicles from milan hypertensive rats. Biochemical and Biophysical Research Communications 1992, 183 (1) , 55-61. https://doi.org/10.1016/0006-291X(92)91608-S
96. Anja Garritsen, Margot W. Beukers, Ad P. Ijzerman, Edward J. Cragoe Jr, Willem Soudijn. The mode of interaction of amiloride and some of its analogues with the adenosine A1 receptor. Neurochemistry International 1992, 20 (2) , 207-213. https://doi.org/10.1016/0197-0186(92)90169-R
97. Thomas Russ, Walter Ried, Frank Ullrich, Ernst Mutschler. Preparation and Diuretic Properties of Novel Amiloride Analogues. Archiv der Pharmazie 1992, 325 (12) , 761-767. https://doi.org/10.1002/ardp.19923251204
98. Dale J. Benos, Sonia Cunningham, R. Randall Baker, K. Beth Beason, Youngsuk Oh, Peter R. Smith. Molecular characteristics of amiloride-sensitive sodium channels. 1992, 31-113. https://doi.org/10.1007/BFb0036122
99. Ian Tannock, Michael Boyer, Asok Kurari, Robert Maidorn, Ken Newell. PROSPECTS FOR DRUGS EXPLOITING LOWER TUMOR pH. 1992, 813-818. https://doi.org/10.1016/B978-0-12-168562-1.50145-2
100. Robert S Haworth, Bernard D Lemire, Diane Crandall, Edward J Cragoe, Larry Fliegel. Characterisation of proton fluxes across the cytoplasmic membrane of the yeast Saccharomyces cerevisiae. Biochimica et Biophysica Acta (BBA) - Bioenergetics 1991, 1098 (1) , 79-89. https://doi.org/10.1016/0005-2728(91)90011-C