Article

Chirped Coherent Anti-Stokes Raman Scattering for High Spectral Resolution Spectroscopy and Chemically Selective Imaging

Department of Chemistry, D31 Hildebrand Hall, University of California, Berkeley, California 94720
J. Phys. Chem. B, 2006, 110 (12), pp 5854–5864
DOI: 10.1021/jp052416a
Publication Date (Web): February 28, 2006
Copyright © 2006 American Chemical Society

Abstract

We describe a simple multiplex vibrational spectroscopic imaging technique based on employing chirped femtosecond pulses in a coherent anti-Stokes Raman scattering (CARS) scheme. Overlap of a femtosecond Stokes pulse with chirped pump/probe pulses introduces a temporal gate that defines the spectral resolution of the technique, allowing single-shot acquisition of high spectral resolution CARS spectra over a several hundred wavenumber bandwidth. Simulated chirped (c-) CARS spectra match the experimental results, quantifying the dependence of the high spectral resolution on the properties of the chirped pulse. c-CARS spectromicroscopy offers promise as a simple and generally applicable high spatial resolution, chemically specific imaging technique for studying complex biological and materials samples.

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Article Views: 406 Times
Received 10 May 2005
Published online 28 February 2006
Published in print 1 March 2006
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