ACS Publications. Most Trusted. Most Cited. Most Read
My Activity
CONTENT TYPES

Figure 1Loading Img

Regeneration of Gold Surfaces Covered by Adsorbed Thiols and Proteins Using Liquid-Phase Hydrogen Peroxide-Mediated UV-Photooxidation

View Author Information
Department of Chemical and Biological Engineering, Drexel University, Philadelphia, Pennsylvania 19104, United States
*Tel.: (215) 895-2236. Fax: (215) 895-5837. E-mail: [email protected]
Cite this: J. Phys. Chem. C 2013, 117, 3, 1335–1341
Publication Date (Web):December 27, 2012
https://doi.org/10.1021/jp307983e
Copyright © 2012 American Chemical Society

    Article Views

    1111

    Altmetric

    -

    Citations

    LEARN ABOUT THESE METRICS
    Other access options
    Supporting Info (1)»

    Abstract

    Abstract Image

    Quartz crystal microbalance (QCM) response of 6-mercapto-1-hexanol chemisorption was used as a model system for examining regeneration of gold (Au) surfaces covered by sulfur-based self-assembled monolayers (SAMs) using a liquid-phase UV-photooxidation (liquid-UVPO) technique. The treatment facilitated oxidation of the Au–thiolate bond in liquid as supported by time-of-flight matrix-free laser desorption/ionization mass spectrometry (LDI-TOF-MS) and post-treatment SAM reformation. The liquid-UVPO technique also showed the ability to regenerate Au surfaces covered by adsorbed proteins, demonstrated using bovine serum albumin (BSA). Comparison with Au regeneration achieved using standard piranha treatment showed the liquid-UVPO technique better preserved the original Au film properties than did piranha treatment. Piranha treatment was found to affect both surface morphology, in terms of surface roughness increase, and film crystal structure, in terms of Au ⟨111⟩ phase fractional decrease, that were relatively absent in the liquid-UVPO treatment based on atomic force microscopy (AFM) and X-ray diffraction (XRD) studies, respectively. This work gives a new liquid-phase technique for regenerating SAM- and protein-covered Au surfaces in liquid that better preserves the original properties of the Au film than standard piranha treatment. Thus, it has potential to improve measurement repeatability in sensing applications, which require Au surface regeneration.

    Read this article

    To access this article, please review the available access options below.

    Get instant access

    Purchase Access

    Read this article for 48 hours. Check out below using your ACS ID or as a guest.

    Recommended

    Access through Your Institution

    You may have access to this article through your institution.

    Your institution does not have access to this content. You can change your affiliated institution below.

    Supporting Information

    ARTICLE SECTIONS
    Jump To

    Additional information is given on mass spectrometry measurements, predicted QCM resonant frequency shifts, binding kinetics calculations, removal of adsorbed proteins from Au using liquid-UVPO, and experimental design. This material is available free of charge via the Internet at http://pubs.acs.org.

    Terms & Conditions

    Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses). Permission may be obtained from ACS for other uses through requests via the RightsLink permission system: http://pubs.acs.org/page/copyright/permissions.html.

    Cited By

    This article is cited by 19 publications.

    1. Sumudu Athukorale, Maleesha De Silva, Allen LaCour, Ganganath S. Perera, Charles U. Pittman, Jr., and Dongmao Zhang . NaHS Induces Complete Nondestructive Ligand Displacement from Aggregated Gold Nanoparticles. The Journal of Physical Chemistry C 2018, 122 (4) , 2137-2144. https://doi.org/10.1021/acs.jpcc.7b10069
    2. Jie Zhong, Xiao Wang, Jianping Du, Lei Wang, Youguo Yan, and Jun Zhang . Combined Molecular Dynamics and Quantum Mechanics Study of Oil Droplet Adsorption on Different Self-Assembly Monolayers in Aqueous Solution. The Journal of Physical Chemistry C 2013, 117 (24) , 12510-12519. https://doi.org/10.1021/jp401047b
    3. Francesco Lavecchia di Tocco, Valentina Botti, Salvatore Cannistraro, Anna Rita Bizzarri. Detection of miR-155 Using Peptide Nucleic Acid at Physiological-like Conditions by Surface Plasmon Resonance and Bio-Field Effect Transistor. Biosensors 2024, 14 (2) , 79. https://doi.org/10.3390/bios14020079
    4. Vira Zakusilova, Evgeny E. Tereshatov, Maria Boltoeva, Charles M. Folden III. Characterization and application of alkanethiolate self-assembled monolayers on Au-coated chips for Ir(IV) and Rh(III) sorption. Applied Surface Science 2024, 642 , 158356. https://doi.org/10.1016/j.apsusc.2023.158356
    5. Margaret S. Lee, Daryl W. Yee, Joshua M. Kubiak, Peter J. Santos, Robert J. Macfarlane. Improving nanoparticle superlattice stability with deformable polymer gels. The Journal of Chemical Physics 2023, 158 (6) https://doi.org/10.1063/5.0130800
    6. Chiara Baldacchini, Antonino Francesco Montanarella, Luca Francioso, Maria Assunta Signore, Salvatore Cannistraro, Anna Rita Bizzarri. A Reliable BioFET Immunosensor for Detection of p53 Tumour Suppressor in Physiological-Like Environment. Sensors 2020, 20 (21) , 6364. https://doi.org/10.3390/s20216364
    7. Ellen Cesewski, Blake N. Johnson. Electrochemical biosensors for pathogen detection. Biosensors and Bioelectronics 2020, 159 , 112214. https://doi.org/10.1016/j.bios.2020.112214
    8. Valentina Di Meo, Andrea Caporale, Alessio Crescitelli, Mohammed Janneh, Elia Palange, Andrea De Marcellis, Marianna Portaccio, Maria Lepore, Ivo Rendina, Menotti Ruvo, Emanuela Esposito. Metasurface based on cross-shaped plasmonic nanoantennas as chemical sensor for surface-enhanced infrared absorption spectroscopy. Sensors and Actuators B: Chemical 2019, 286 , 600-607. https://doi.org/10.1016/j.snb.2019.02.014
    9. Alexander P. Haring, Ellen Cesewski, Blake N. Johnson. Piezoelectric Cantilever Biosensors for Label-free, Real-time Detection of DNA and RNA. 2017, 247-262. https://doi.org/10.1007/978-1-4939-6911-1_17
    10. S. N. Ovchinnikova. Comparative electrochemical study of self-assembly of octanethiol from aqueous and aqueous ethanol solutions on a gold electrode. Russian Journal of Electrochemistry 2016, 52 (3) , 260-267. https://doi.org/10.1134/S1023193516030083
    11. Vivien Lacour, Céline Elie-Caille, Thérèse Leblois, Jan J. Dubowski. Regeneration of a thiolated and antibody functionalized GaAs (001) surface using wet chemical processes. Biointerphases 2016, 11 (1) https://doi.org/10.1116/1.4942878
    12. Blake N. Johnson, Raj Mutharasan. Biosensors. 2015, 391-426. https://doi.org/10.1002/9783527676330.ch16
    13. S. N. Ovchinnikova, A. Zh. Medvedev. Desorption of octanethiol from gold electrode surface during its electrochemical cleaning. Russian Journal of Electrochemistry 2015, 51 (4) , 287-293. https://doi.org/10.1134/S1023193515040084
    14. Edward W. Elliott, Richard D. Glover, James E. Hutchison. Removal of Thiol Ligands from Surface-Confined Nanoparticles without Particle Growth or Desorption. ACS Nano 2015, 9 (3) , 3050-3059. https://doi.org/10.1021/nn5072528
    15. Augusta M. Levendorf, Shi-Gang Sun, YuYe J. Tong. In Situ FT-IR Investigation of Methanol and CO Electrooxidation on Cubic and Octahedral/Tetrahedral Pt Nanoparticles Having Residual PVP. Electrocatalysis 2014, 5 (3) , 248-255. https://doi.org/10.1007/s12678-014-0186-1
    16. Mingming Yu, Dongzhi Liu, Wei Li, Xueqin Zhou. The negative temperature coefficient resistivities of Ag2SAg core–shell structures. Applied Surface Science 2014, 288 , 158-165. https://doi.org/10.1016/j.apsusc.2013.09.172
    17. Augusta M. Levendorf, De-Jun Chen, Christopher L. Rom, Yangwei Liu, YuYe J. Tong. Electrochemical and in situ ATR-SEIRAS investigations of methanol and CO electro-oxidation on PVP-free cubic and octahedral/tetrahedral Pt nanoparticles. RSC Adv. 2014, 4 (41) , 21284-21293. https://doi.org/10.1039/C4RA00815D
    18. Blake N. Johnson, Raj Mutharasan. Reduction of nonspecific protein adsorption on cantilever biosensors caused by transverse resonant mode vibration. The Analyst 2014, 139 (5) , 1112. https://doi.org/10.1039/c3an01675g
    19. Blake N. Johnson, Raj Mutharasan. Electrochemical piezoelectric-excited millimeter-sized cantilever (ePEMC) for simultaneous dual transduction biosensing. The Analyst 2013, 138 (21) , 6365. https://doi.org/10.1039/c3an01353g

    Pair your accounts.

    Export articles to Mendeley

    Get article recommendations from ACS based on references in your Mendeley library.

    Pair your accounts.

    Export articles to Mendeley

    Get article recommendations from ACS based on references in your Mendeley library.

    You’ve supercharged your research process with ACS and Mendeley!

    STEP 1:
    Click to create an ACS ID

    Please note: If you switch to a different device, you may be asked to login again with only your ACS ID.

    Please note: If you switch to a different device, you may be asked to login again with only your ACS ID.

    Please note: If you switch to a different device, you may be asked to login again with only your ACS ID.

    MENDELEY PAIRING EXPIRED
    Your Mendeley pairing has expired. Please reconnect