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Platinum-Catalyzed Tandem Indole Annulation/Arylation for the Synthesis of Diindolylmethanes and Indolo[3,2-b]carbazoles

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Download Hi-Res ImageDownload to MS-PowerPointCite This:Org. Lett. 2013, 15, 16, 4162-4165
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    Platinum-Catalyzed Tandem Indole Annulation/Arylation for the Synthesis of Diindolylmethanes and Indolo[3,2-b]carbazoles
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    School of Pharmacy, University of Wisconsin, Madison, Wisconsin 53705, United States, and Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States
    [email protected]
    †School of Pharmacy.
    ‡Department of Chemistry.
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    Organic Letters

    Cite this: Org. Lett. 2013, 15, 16, 4162–4165
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    https://doi.org/10.1021/ol4018408
    Published August 5, 2013
    Copyright © 2013 American Chemical Society
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    Abstract

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    Various diindolylmethanes were prepared from propargylic ethers and substituted indoles via a platinum-catalyzed tandem indole annulation/arylation cascade. The resulting diindolylmethanes could be converted to natural product malassezin by formylation or indolo[3,2-b]carbazoles by cyclization.

    Copyright © 2013 American Chemical Society

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    This article is cited by 47 publications.

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    Cite this: Org. Lett. 2013, 15, 16, 4162–4165
    Click to copy citationCitation copied!
    https://doi.org/10.1021/ol4018408
    Published August 5, 2013
    Copyright © 2013 American Chemical Society
    Request reuse permissions

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