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3D Printed Programmable Release Capsules

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Department of Mechanical and Aerospace Engineering and Department of Electrical Engineering, Princeton University, Princeton, New Jersey 08544, United States
§ Department of Mechanical Engineering, University of Minnesota, Minneapolis, Minnesota 55455, United States
Department of Mechanical Engineering and Materials Science, Washington University in St. Louis, St. Louis, Missouri 63130, United States
*Tel (609) 542-0275; e-mail [email protected]
Cite this: Nano Lett. 2015, 15, 8, 5321–5329
Publication Date (Web):June 4, 2015
Copyright © 2015 American Chemical Society

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    The development of methods for achieving precise spatiotemporal control over chemical and biomolecular gradients could enable significant advances in areas such as synthetic tissue engineering, biotic–abiotic interfaces, and bionanotechnology. Living organisms guide tissue development through highly orchestrated gradients of biomolecules that direct cell growth, migration, and differentiation. While numerous methods have been developed to manipulate and implement biomolecular gradients, integrating gradients into multiplexed, three-dimensional (3D) matrices remains a critical challenge. Here we present a method to 3D print stimuli-responsive core/shell capsules for programmable release of multiplexed gradients within hydrogel matrices. These capsules are composed of an aqueous core, which can be formulated to maintain the activity of payload biomolecules, and a poly(lactic-co-glycolic) acid (PLGA, an FDA approved polymer) shell. Importantly, the shell can be loaded with plasmonic gold nanorods (AuNRs), which permits selective rupturing of the capsule when irradiated with a laser wavelength specifically determined by the lengths of the nanorods. This precise control over space, time, and selectivity allows for the ability to pattern 2D and 3D multiplexed arrays of enzyme-loaded capsules along with tunable laser-triggered rupture and release of active enzymes into a hydrogel ambient. The advantages of this 3D printing-based method include (1) highly monodisperse capsules, (2) efficient encapsulation of biomolecular payloads, (3) precise spatial patterning of capsule arrays, (4) “on the fly” programmable reconfiguration of gradients, and (5) versatility for incorporation in hierarchical architectures. Indeed, 3D printing of programmable release capsules may represent a powerful new tool to enable spatiotemporal control over biomolecular gradients.

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    Additional experimental details with materials, methods, and figures. The Supporting Information is available free of charge on the ACS Publications website at DOI: 10.1021/acs.nanolett.5b01688.

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    10. Elmeri Lahtinen, Lotta Turunen, Mikko M. Hänninen, Kalle Kolari, Heikki M. Tuononen, Matti Haukka. Fabrication of Porous Hydrogenation Catalysts by a Selective Laser Sintering 3D Printing Technique. ACS Omega 2019, 4 (7) , 12012-12017.
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    12. Linda M. Guiney, Nikhita D. Mansukhani, Adam E. Jakus, Shay G. Wallace, Ramille N. Shah, Mark C. Hersam. Three-Dimensional Printing of Cytocompatible, Thermally Conductive Hexagonal Boron Nitride Nanocomposites. Nano Letters 2018, 18 (6) , 3488-3493.
    13. Milena Nadgorny, Amir Ameli. Functional Polymers and Nanocomposites for 3D Printing of Smart Structures and Devices. ACS Applied Materials & Interfaces 2018, 10 (21) , 17489-17507.
    14. Cole D. Brubaker, Michael A. Davies, James R. McBride, Sandra J. Rosenthal, G. Kane Jennings, Douglas E. Adams. Nondestructive Evaluation and Detection of Defects in 3D Printed Materials Using the Optical Properties of Gold Nanoparticles. ACS Applied Nano Materials 2018, 1 (3) , 1377-1384.
    15. Samuel Clark Ligon, Robert Liska, Jürgen Stampfl, Matthias Gurr, and Rolf Mülhaupt . Polymers for 3D Printing and Customized Additive Manufacturing. Chemical Reviews 2017, 117 (15) , 10212-10290.
    16. Milena Nadgorny, Zeyun Xiao, Chao Chen, and Luke A. Connal . Three-Dimensional Printing of pH-Responsive and Functional Polymers on an Affordable Desktop Printer. ACS Applied Materials & Interfaces 2016, 8 (42) , 28946-28954.
    17. Rock J. Mancini, Samantha J. Paluck, Erhan Bat, and Heather D. Maynard . Encapsulated Hydrogels by E-beam Lithography and Their Use in Enzyme Cascade Reactions. Langmuir 2016, 32 (16) , 4043-4051.
    18. Limei Tian, Sirimuvva Tadepalli, Max Fei, Jeremiah J. Morrissey, Evan D. Kharasch, and Srikanth Singamaneni . Off-Resonant Gold Superstructures as Ultrabright Minimally Invasive Surface-Enhanced Raman Scattering (SERS) Probes. Chemistry of Materials 2015, 27 (16) , 5678-5684.
    19. Md. Habibur Rahman, Nilufar Yasmin Liza, Khan Rajib Hossain, Dipika Ramdas Kalambhe, Md. Abu Shyeed, Dilwar Hossain Noor. Additive manufacturing in nano drug delivery systems. Pharmaceutical Science Advances 2024, 2 , 100036.
    20. Manoj K. Shukla, Charles M. Luft, Ashlyn M. Koval, William A. Pisani, Robert W. Lamb, Levi A. Lystrom, Brian D. Etz, Katarina M. Pittman, Michael R. Roth, Caitlin G. Bresnahan, Timothy C. Schutt, Glen R. Jenness, Harley R. McAlexander. Emerging Materials and Environment: A Brief Introduction. 2024, 1-78.
    21. Atheer Awad, Abdul W. Basit, Simon Gaisford, Alvaro Goyanes. Forging a Personalised Path: 3D Printing’s Role in Healthcare Transformation. 2024, 257-272.
    22. Lihuang Wu, Junhua Li, Yuqi Wang, Xinyue Zhao, Yiyan He, Hongli Mao, Wenbo Tang, Rong Liu, Kui Luo, Zhongwei Gu. Engineered Hierarchical Microdevices Enable Pre‐Programmed Controlled Release for Postsurgical and Unresectable Cancer Treatment. Advanced Materials 2023, 35 (51)
    23. Darya O. Shavronskaya, Alina O. Noskova, Natalia N. Skvortsova, Parise Adadi, Elena A. Nazarova, . Encapsulation of Hydrophobic Bioactive Substances for Food Applications: Carriers, Techniques, and Biosafety. Journal of Food Processing and Preservation 2023, 2023 , 1-21.
    24. Zijing Zhou, Weijie Tang, Jinfu Yang, Chengming Fan. Application of 4D printing and bioprinting in cardiovascular tissue engineering. Biomaterials Science 2023, 11 (19) , 6403-6420.
    25. Souvik Ghosh, Siddhi Chaudhuri, Partha Roy, Debrupa Lahiri. 4D Printing in Biomedical Engineering: a State-of-the-Art Review of Technologies, Biomaterials, and Application. Regenerative Engineering and Translational Medicine 2023, 9 (3) , 339-365.
    26. Muneeb Ullah, Abdul Wahab, Shahid Ullah Khan, Muhammad Naeem, Khalil ur Rehman, Haider Ali, Aziz Ullah, Amjad Khan, Nauman Rahim Khan, Waleed Y. Rizg, Khaled M. Hosny, Mohammed Alissa, Moutaz Y. Badr, Hala M. Alkhalidi. 3D printing technology: A new approach for the fabrication of personalized and customized pharmaceuticals. European Polymer Journal 2023, 195 , 112240.
    27. Bin Xie, Weixian Zhao, Xiaobing Luo, Run Hu. Alignment engineering in thermal materials. Materials Science and Engineering: R: Reports 2023, 154 , 100738.
    28. Zhiqiang Zhu, Tianao Chen, Yuanqing Zhu, Fangsheng Huang, Kai Mu, Ting Si, Ronald X. Xu. Programmable pulsed aerodynamic printing for multi-interface composite manufacturing. Matter 2023, 6 (6) , 2034-2051.
    29. Zichen Xu, Zehao Wu, Mingzhe Yuan, Yuanhe Chen, Wei Ge, Qingsong Xu. Versatile magnetic hydrogel soft capsule microrobots for targeted delivery. iScience 2023, 26 (5) , 106727.
    30. James Mason, Daniel Öhlund. Key aspects for conception and construction of co-culture models of tumor-stroma interactions. Frontiers in Bioengineering and Biotechnology 2023, 11
    31. Rahul M. Visalakshan, Mary K. Lowrey, Mauricio G. C. Sousa, Haylie R. Helms, Abrar Samiea, Carolyn E. Schutt, Josh M. Moreau, Luiz E. Bertassoni. Opportunities and challenges to engineer 3D models of tumor-adaptive immune interactions. Frontiers in Immunology 2023, 14
    32. Keiki Muranaka, Takuro Niidome, Maria Leilani Torres-Mapa, Alexander Heisterkamp, Mitsuhiro Terakawa. Formation of Gold Nanoparticles inside a Hydrogel by Multiphoton Photoreduction for Plasmonic Sensing. Plasmonics 2023, 18 (2) , 751-760.
    33. Jie Li, Bogdan V. Parakhonskiy, Andre G. Skirtach. A decade of developing applications exploiting the properties of polyelectrolyte multilayer capsules. Chemical Communications 2023, 59 (7) , 807-835.
    34. Atheer Awad, Alvaro Goyanes, Abdul W. Basit, Ahmed S. Zidan, Changxue Xu, Wei Li, Roger J. Narayan, Roland K. Chen. A Review of State-of-the-Art on Enabling Additive Manufacturing Processes for Precision Medicine. Journal of Manufacturing Science and Engineering 2023, 145 (1)
    35. Prashant Pingale, Shilpa Dawre, Vividha Dhapte-Pawar, Namdev Dhas, Amarjitsing Rajput. Advances in 4D printing: from stimulation to simulation. Drug Delivery and Translational Research 2023, 13 (1) , 164-188.
    36. Zhen Wang, Lei Xiang, Feng Lin, Yunkai Tang, Wenguo Cui. 3D bioprinting of emulating homeostasis regulation for regenerative medicine applications. Journal of Controlled Release 2023, 353 , 147-165.
    37. Md Omar Faruque, Yugyung Lee, Gerald J. Wyckoff, Chi H. Lee. Application of 4D printing and AI to cardiovascular devices. Journal of Drug Delivery Science and Technology 2023, 609 , 104162.
    38. Hanuma Reddy Tiyyagura, Peter Majerič, Žiga Jelen, Rebeka Rudolf. Gold nano-inks: synthesis and characterizations. 2023, 53-73.
    39. Atheer Awad, Abdul W. Basit. 3D and 4D Printing in Digital Healthcare. 2023, 1-23.
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    64. Shaohui Zhang, Xiang Duan, Chuan Li, Ming Liang. Pre-classified reservoir computing for the fault diagnosis of 3D printers. Mechanical Systems and Signal Processing 2021, 146 , 106961.
    65. Maria P. Nikolova, K. Karthik, Murthy S. Chavali. Nanofunctionalized 3D printing. 2021, 457-504.
    66. Qingzhen Yang, Xuemeng Lv, Bin Gao, Yuan Ji, Feng Xu. Mechanics of hydrogel-based bioprinting: From 3D to 4D. 2021, 285-318.
    67. Qinhong Wei, Hangjie Li, Guoguo Liu, Yingluo He, Yang Wang, Yen Ee Tan, Ding Wang, Xiaobo Peng, Guohui Yang, Noritatsu Tsubaki. Metal 3D printing technology for functional integration of catalytic system. Nature Communications 2020, 11 (1)
    68. Pallab Datta, Madhuri Dey, Zaman Ataie, Derya Unutmaz, Ibrahim T. Ozbolat. 3D bioprinting for reconstituting the cancer microenvironment. npj Precision Oncology 2020, 4 (1)
    69. Raphaël F. Canadas, Pedro Patrício, Virginia Brancato, Luca Gasperini, David Caballero, Ricardo A. Pires, João B. Costa, Hélder Pereira, Ping Yong, Lucília P. da Silva, Jie Chen, Subhas C. Kundu, Nuno A.M. Araújo, Rui L. Reis, Alexandra P. Marques, Joaquim M. Oliveira. Convection patterns gradients of non-living and living micro-entities in hydrogels. Applied Materials Today 2020, 21 , 100859.
    70. Mojtaba Falahati, Parvaneh Ahmadvand, Shahriar Safaee, Yu-Chung Chang, Zhaoyuan Lyu, Roland Chen, Lei Li, Yuehe Lin. Smart polymers and nanocomposites for 3D and 4D printing. Materials Today 2020, 40 , 215-245.
    71. Harald Rupp, Wolfgang H. Binder. 3D Printing of Core–Shell Capsule Composites for Post‐Reactive and Damage Sensing Applications. Advanced Materials Technologies 2020, 5 (11)
    72. Shuangshuang Mao, Yuan Pang, Tiankun Liu, Yongchun Shao, Jianyu He, Huayu Yang, Yilei Mao, Wei Sun. Bioprinting of in vitro tumor models for personalized cancer treatment: a review. Biofabrication 2020, 12 (4) , 042001.
    73. Zhen Jiang, Broden Diggle, Ming Li Tan, Jekaterina Viktorova, Christopher W Bennett, Luke A. Connal. Extrusion 3D Printing of Polymeric Materials with Advanced Properties. Advanced Science 2020, 7 (17) , 2001379.
    74. Fan Zhang, Martin W. King. Biodegradable Polymers as the Pivotal Player in the Design of Tissue Engineering Scaffolds. Advanced Healthcare Materials 2020, 9 (13)
    75. Hing Jii Mea, Luis Delgadillo, Jiandi Wan. On-demand modulation of 3D-printed elastomers using programmable droplet inclusions. Proceedings of the National Academy of Sciences 2020, 117 (26) , 14790-14797.
    76. Hui Wang, Haitao Liu, Fan He, Wenwen Chen, Xu Zhang, Mengqian Zhao, Li Wang, Jianhua Qin. Flexible Generation of Multi‐Aqueous Core Hydrogel Capsules Using Microfluidic Aqueous Two‐Phase System. Advanced Materials Technologies 2020, 5 (6)
    77. Yu. A. Satskaya, S. A. Sotnik, D. A. Lagoshnyak, S. V. Kolotilov. Compositions Based on Microporous Coordination Polymers for the Formation of Arbitrarily Shaped 3D Objects. Russian Journal of Coordination Chemistry 2020, 46 (5) , 350-354.
    78. Hiroyuki Tetsuka, Su Ryon Shin. Materials and technical innovations in 3D printing in biomedical applications. Journal of Materials Chemistry B 2020, 8 (15) , 2930-2950.
    79. Elia A. Guzzi, Mark W. Tibbitt. Additive Manufacturing of Precision Biomaterials. Advanced Materials 2020, 32 (13)
    80. Margaret E. Prendergast, Jason A. Burdick. Recent Advances in Enabling Technologies in 3D Printing for Precision Medicine. Advanced Materials 2020, 32 (13)
    81. Brian Elder, Rajan Neupane, Eric Tokita, Udayan Ghosh, Samuel Hales, Yong Lin Kong. Nanomaterial Patterning in 3D Printing. Advanced Materials 2020, 32 (17)
    82. Yuanfang Zhang, Wei Fang, Yichun Zhao, Zhihong Liu, Shaoyun Chen, Chenlong Hu, Jiyan Liu, Xueqing Liu. Electric field‐driven preparation of elastomer/plastic nanoparticles gradient films with enhanced damping property. Journal of Applied Polymer Science 2020, 137 (8)
    83. Aqib Muzaffar, M. Basheer Ahamed, Kalim Deshmukh, Tomáš Kovářík, Tomáš Křenek, S. K. Khadheer Pasha. 3D and 4D printing of pH-responsive and functional polymers and their composites. 2020, 85-117.
    84. Alexander P. Haring, Blake N. Johnson. Brain-on-a-chip systems for modeling disease pathogenesis. 2020, 215-232.
    85. David Caballero, Rui L. Reis, Subhas C. Kundu. Trends in biomaterials for three-dimensional cancer modeling. 2020, 3-41.
    86. Matthew L. Bedell, Jason L. Guo, Virginia Y. Xie, Adam M. Navara, Antonios G. Mikos. Polymer scaffold fabrication. 2020, 295-315.
    87. Daeha Joung, Nicolas S. Lavoie, Shuang‐Zhuang Guo, Sung Hyun Park, Ann M. Parr, Michael C. McAlpine. 3D Printed Neural Regeneration Devices. Advanced Functional Materials 2020, 30 (1)
    88. Alexander P. Haring, Emily G. Thompson, Raymundo D. Hernandez, Sahil Laheri, Megan E. Harrigan, Taylor Lear, Harald Sontheimer, Blake N. Johnson. 3D Printed Multiplexed Competitive Migration Assays with Spatially Programmable Release Sources. Advanced Biosystems 2020, 4 (1)
    89. Sidonie Aubert, Marine Bezagu, Alan C. Spivey, Stellios Arseniyadis. Spatial and temporal control of chemical processes. Nature Reviews Chemistry 2019, 3 (12) , 706-722.
    90. Chong Li, Jiancheng Wang, Yiguang Wang, Huile Gao, Gang Wei, Yongzhuo Huang, Haijun Yu, Yong Gan, Yongjun Wang, Lin Mei, Huabing Chen, Haiyan Hu, Zhiping Zhang, Yiguang Jin. Recent progress in drug delivery. Acta Pharmaceutica Sinica B 2019, 9 (6) , 1145-1162.
    91. Kota Inohara, Shusaku Asano, Taisuke Maki, Kazuhiro Mae. Synthesis of Small Lipid Nanoparticles Using an Inkjet Mixing System Aiming to Reduce Drug Loss. Chemical Engineering & Technology 2019, 42 (10) , 2061-2066.
    92. Yuan Siang Lui, Wan Ting Sow, Lay Poh Tan, Yunlong Wu, Yuekun Lai, Huaqiong Li. 4D printing and stimuli-responsive materials in biomedical aspects. Acta Biomaterialia 2019, 92 , 19-36.
    93. Arman Naderi, Nirveek Bhattacharjee, Albert Folch. Digital Manufacturing for Microfluidics. Annual Review of Biomedical Engineering 2019, 21 (1) , 325-364.
    94. Yuxin Tong, Ezgi Kucukdeger, Justin Halper, Ellen Cesewski, Elena Karakozoff, Alexander P. Haring, David McIlvain, Manjot Singh, Nikita Khandelwal, Alex Meholic, Sahil Laheri, Akshay Sharma, Blake N. Johnson, . Low-cost sensor-integrated 3D-printed personalized prosthetic hands for children with amniotic band syndrome: A case study in sensing pressure distribution on an anatomical human-machine interface (AHMI) using 3D-printed conformal electrode arrays. PLOS ONE 2019, 14 (3) , e0214120.
    95. Ankit Jain, Kuldeep K. Bansal, Ankita Tiwari, Ari Rosling, Jessica M. Rosenholm. Role of Polymers in 3D Printing Technology for Drug Delivery - An Overview. Current Pharmaceutical Design 2019, 24 (42) , 4979-4990.
    96. Fanben Meng, Carolyn M. Meyer, Daeha Joung, Daniel A. Vallera, Michael C. McAlpine, Angela Panoskaltsis‐Mortari. 3D Bioprinted In Vitro Metastatic Models via Reconstruction of Tumor Microenvironments. Advanced Materials 2019, 31 (10)
    97. Wanting Dai, Huilong Guo, Bo Gao, Miaoliang Ruan, Lanqin Xu, Jianping Wu, Thomas Brett Kirk, Jiake Xu, Dong Ma, Wei Xue. Double network shape memory hydrogels activated by near-infrared with high mechanical toughness, nontoxicity, and 3D printability. Chemical Engineering Journal 2019, 356 , 934-949.
    98. A. Sydney Gladman, Manuel Garcia-Leiner, Alexis F. Sauer-Budge, . Emerging polymeric materials in additive manufacturing for use in biomedical applications. AIMS Bioengineering 2019, 6 (1) , 1-20.
    99. Guillaume Bouguéon, Tina Kauss, Bérangère Dessane, Philippe Barthélémy, Sylvie Crauste-Manciet. Micro- and nano-formulations for bioprinting and additive manufacturing. Drug Discovery Today 2019, 24 (1) , 163-178.
    100. Sean M. Bittner, Jason L. Guo, Antonios G. Mikos. Spatiotemporal control of growth factors in three-dimensional printed scaffolds. Bioprinting 2018, 12 , e00032.
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