ACS Publications. Most Trusted. Most Cited. Most Read
Low-Dose 4D-STEM Tomography for Beam-Sensitive Nanocomposites

OR SEARCH CITATIONS

My Activity
Publications

Figure 1Loading Img
Download Hi-Res ImageDownload to MS-PowerPointCite This:ACS Materials Lett. 2024, 6, 1, 165-173
    Letter

    Low-Dose 4D-STEM Tomography for Beam-Sensitive Nanocomposites
    Click to copy article linkArticle link copied!

    • Milena Hugenschmidt
      Milena Hugenschmidt
      EMAT and NanoLab, University of Antwerp, Groenenborgerlaan 171, Antwerp 2020, Belgium
      More by Milena Hugenschmidt
      Orcidhttps://orcid.org/0000-0001-5020-9302
    • Daen Jannis
      Daen Jannis
      EMAT and NanoLab, University of Antwerp, Groenenborgerlaan 171, Antwerp 2020, Belgium
      More by Daen Jannis
    • Ajinkya Anil Kadu
      Ajinkya Anil Kadu
      EMAT and NanoLab, University of Antwerp, Groenenborgerlaan 171, Antwerp 2020, Belgium
      Centrum Wiskunde & Informatica, Science Park 123, 1098 XG Amsterdam, The Netherlands
      More by Ajinkya Anil Kadu
      Orcidhttps://orcid.org/0000-0003-0853-1378
    • Lukas Grünewald
      Lukas Grünewald
      EMAT and NanoLab, University of Antwerp, Groenenborgerlaan 171, Antwerp 2020, Belgium
      More by Lukas Grünewald
    • Sarah De Marchi
      Sarah De Marchi
      CINBIO, Universidade de Vigo, Departamento de Química Física, Campus Universitario As Lagoas, Marcosende, 36310 Vigo, Spain
      Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, 36310 Vigo, Spain
      More by Sarah De Marchi
    • Jorge Pérez-Juste
      Jorge Pérez-Juste
      CINBIO, Universidade de Vigo, Departamento de Química Física, Campus Universitario As Lagoas, Marcosende, 36310 Vigo, Spain
      Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, 36310 Vigo, Spain
      More by Jorge Pérez-Juste
      Orcidhttps://orcid.org/0000-0002-4614-1699
    • Johan Verbeeck
      Johan Verbeeck
      EMAT and NanoLab, University of Antwerp, Groenenborgerlaan 171, Antwerp 2020, Belgium
      More by Johan Verbeeck
    • Sandra Van Aert*
      Sandra Van Aert
      EMAT and NanoLab, University of Antwerp, Groenenborgerlaan 171, Antwerp 2020, Belgium
      *[email protected]
      More by Sandra Van Aert
    • Sara Bals*
      Sara Bals
      EMAT and NanoLab, University of Antwerp, Groenenborgerlaan 171, Antwerp 2020, Belgium
      *[email protected]
      More by Sara Bals
      Orcidhttps://orcid.org/0000-0002-4249-8017
    Other Access OptionsSupporting Information (4)

    ACS Materials Letters

    Cite this: ACS Materials Lett. 2024, 6, 1, 165–173
    Click to copy citationCitation copied!
    https://doi.org/10.1021/acsmaterialslett.3c01042
    Published December 11, 2023
    Copyright © 2023 American Chemical Society
    Request reuse permissions

    Abstract

    Click to copy section linkSection link copied!
    Abstract Image

    Electron tomography is essential for investigating the three-dimensional (3D) structure of nanomaterials. However, many of these materials, such as metal–organic frameworks (MOFs), are extremely sensitive to electron radiation, making it difficult to acquire a series of projection images for electron tomography without inducing electron-beam damage. Another significant challenge is the high contrast in high-angle annular dark field scanning transmission electron microscopy that can be expected for nanocomposites composed of a metal nanoparticle and an MOF. This strong contrast leads to so-called metal artifacts in the 3D reconstruction. To overcome these limitations, we here present low-dose electron tomography based on four-dimensional scanning transmission electron microscopy (4D-STEM) data sets, collected using an ultrafast and highly sensitive direct electron detector. As a proof of concept, we demonstrate the applicability of the method for an Au nanostar embedded in a ZIF-8 MOF, which is of great interest for applications in various fields, including drug delivery.

    Copyright © 2023 American Chemical Society

    Subjects

    what are subjects

    Read this article

    To access this article, please review the available access options below.

    Get instant access

    Purchase Access

    Read this article for 48 hours. Check out below using your ACS ID or as a guest.

    Recommended

    Access through Your Institution

    You may have access to this article through your institution.

    Your institution does not have access to this content. Add or change your institution or let them know you’d like them to include access.

    Supporting Information

    Click to copy section linkSection link copied!

    The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acsmaterialslett.3c01042.

    • 3D reconstruction (MPG)

    • Original and denoised tilt series of the MOF (MP4)

    • Original and denoised tilt series of the NP (MP4)

    • Azimuthally integrated scattered intensities, description of the projection requirement, discussion of the denoising algorithm and the reconstruction quality, orthoslices of the reconstructed MOF and NP, exemplary denoised vSTEM images and forward projections, evaluation of shrinkage, low-resolution TEM images of the NP@ZIF-8 composite as well as UV–vis spectra of the NP and the composite, and tilt series of the MOF and the NP (original and denoised) (PDF)

    Terms & Conditions

    Electronic Supporting Information files are available without a subscription to ACS Web Editions. The American Chemical Society holds a copyright ownership interest in any copyrightable Supporting Information. Files available from the ACS website may be downloaded for personal use only. Users are not otherwise permitted to reproduce, republish, redistribute, or sell any Supporting Information from the ACS website, either in whole or in part, in either machine-readable form or any other form without permission from the American Chemical Society. For permission to reproduce, republish and redistribute this material, requesters must process their own requests via the RightsLink permission system. Information about how to use the RightsLink permission system can be found at http://pubs.acs.org/page/copyright/permissions.html.

    Cited By

    Click to copy section linkSection link copied!

    This article is cited by 1 publications.

    1. Sara Bals, Luis M. Liz-Marzán, Wolfgang J. Parak, Katherine A. Willets, Huolin L. Xin. Best Practices for Using Microscopy Data in Manuscripts: From Pretty Pictures to Scientific Evidence. ACS Nano 2024, 18 (21) , 13453-13457. https://doi.org/10.1021/acsnano.4c05299
    Download PDF
    Go to ACS Materials Letters
    Get e-Alerts
    Get e-Alerts

    ACS Materials Letters

    Cite this: ACS Materials Lett. 2024, 6, 1, 165–173
    Click to copy citationCitation copied!
    https://doi.org/10.1021/acsmaterialslett.3c01042
    Published December 11, 2023
    Copyright © 2023 American Chemical Society
    Request reuse permissions

    Article Views

    1236

    Altmetric

    -

    Citations

    1
    Learn about these metrics

    Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.

    Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.

    The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated.