Bioconcentration and Metabolic Effects of Emerging PFOS Alternatives in Developing Zebrafish

Click to copy article linkArticle link copied!

This article is cited by 90 publications.

1. Boxiang Zhang, Qing Li, Wensheng Wang, Mingming Tian, Dan Xu, Ying Xie. PFOS and Its Substitute OBS Cause Endothelial Dysfunction to Promote Atherogenesis in ApoE–/– Mice. Environment & Health 2025, Article ASAP.
2. Xin Li, Minmin Hou, Feng Zhang, Zhengquan Ji, Yaqi Cai, Yali Shi. Per- and Polyfluoroalkyl Substances and Female Health Concern: Gender-based Accumulation Differences, Adverse Outcomes, and Mechanisms. Environmental Science & Technology 2025, 59 (3) , 1469-1486. https://doi.org/10.1021/acs.est.4c08701
3. Shen-Pan Li, Hui-Xian Zeng, Shuang-Jian Qin, Qing-Qing Li, Lu-Yin Wu, Qi-Zhen Wu, Li-Zi Lin, Guang-Hui Dong, Xiao-Wen Zeng. Effects on Synaptic Plasticity Markers in Fetal Mice and HT22 Neurons upon F-53B Exposure: The Role of PKA Cytoplasmic Retention. Environment & Health 2024, 2 (11) , 776-785. https://doi.org/10.1021/envhealth.4c00098
4. Hyojin Lee, John D.H. Stead, Andrew Williams, Sergio A. Cortés Ramírez, Ella Atlas, Jan A. Mennigen, Jason M. O’Brien, Carole Yauk. Empirical Characterization of False Discovery Rates of Differentially Expressed Genes and Transcriptomic Benchmark Concentrations in Zebrafish Embryos. Environmental Science & Technology 2024, 58 (14) , 6128-6137. https://doi.org/10.1021/acs.est.3c10543
5. Jie Zhang, Xinghui Xia, Chuanxin Ma, Shangwei Zhang, Kaixuan Li, Yingying Yang, Zhifeng Yang. Nanoplastics Affect the Bioaccumulation and Gut Toxicity of Emerging Perfluoroalkyl Acid Alternatives to Aquatic Insects (Chironomus kiinensis): Importance of Plastic Surface Charge. ACS Nano 2024, 18 (7) , 5752-5765. https://doi.org/10.1021/acsnano.3c12009
6. Xin Liu, Lei Zhang, Jiaying Liu, Gerili Zaya, Yuxin Wang, Qian Xiang, Jingguang Li, Yongning Wu. 6:2 Chlorinated Polyfluoroalkyl Ether Sulfonates Exert Stronger Thyroid Homeostasis Disruptive Effects in Newborns than Perfluorooctanesulfonate: Evidence Based on Bayesian Benchmark Dose Values from a Population Study. Environmental Science & Technology 2023, 57 (31) , 11489-11498. https://doi.org/10.1021/acs.est.3c03952
7. Mei-Xia Ye, Xiao-Jun Luo, Yu Liu, Chu-Hong Zhu, Qun-Jie Feng, Yan-Hong Zeng, Bi-Xian Mai. Sex-Specific Bioaccumulation, Maternal Transfer, and Tissue Distribution of Legacy and Emerging Per- and Polyfluoroalkyl Substances in Snakes (Enhydris chinensis) and the Impact of Pregnancy. Environmental Science & Technology 2023, 57 (11) , 4481-4491. https://doi.org/10.1021/acs.est.2c09063
8. Ross M. Warner, Lisa M. Sweeney, Brett A. Hayhurst, Michael L. Mayo. Toxicokinetic Modeling of Per- and Polyfluoroalkyl Substance Concentrations within Developing Zebrafish (Danio rerio) Populations. Environmental Science & Technology 2022, 56 (18) , 13189-13199. https://doi.org/10.1021/acs.est.2c02942
9. Minmin Hou, Qi Jin, Guangshui Na, Yaqi Cai, Yali Shi. Emissions, Isomer-Specific Environmental Behavior, and Transformation of OBS from One Major Fluorochemical Manufacturing Facility in China. Environmental Science & Technology 2022, 56 (12) , 8103-8113. https://doi.org/10.1021/acs.est.2c01287
10. Bo Zhang, Yuan He, Guang Yang, Bingyao Chen, Yiming Yao, Hongwen Sun, Kurunthachalam Kannan, Tao Zhang. Legacy and Emerging Poly- and Perfluoroalkyl Substances in Finless Porpoises from East China Sea: Temporal Trends and Tissue-Specific Accumulation. Environmental Science & Technology 2022, 56 (10) , 6113-6122. https://doi.org/10.1021/acs.est.1c00062
11. Liquan Liu, Shanshan Deng, Yixiang Bao, Jun Huang, Gang Yu. Degradation of OBS (Sodium p-Perfluorous Nonenoxybenzenesulfonate) as a Novel Per- and Polyfluoroalkyl Substance by UV/Persulfate and UV/Sulfite: Fluorinated Intermediates and Treatability in Fluoroprotein Foam. Environmental Science & Technology 2022, 56 (10) , 6201-6211. https://doi.org/10.1021/acs.est.1c03210
12. Caiyun Wang, Chanlin Fang, Caihong Wang, Cuiyuan Jin, Mingrong Qian, Yuanxiang Jin. Maternal Sodium p-Perfluorous Nonenoxybenzene Sulfonate Exposure Disturbed Lipid Metabolism and Induced an Imbalance in Tyrosine Metabolism in the F1 Generation of Mice. Chemical Research in Toxicology 2022, 35 (4) , 651-662. https://doi.org/10.1021/acs.chemrestox.1c00424
13. Weizong Li, Huizhen Li, Dainan Zhang, Yujun Tong, Faxu Li, Fei Cheng, Zhoubing Huang, Jing You. Legacy and Emerging Per- and Polyfluoroalkyl Substances Behave Distinctly in Spatial Distribution and Multimedia Partitioning: A Case Study in the Pearl River, China. Environmental Science & Technology 2022, 56 (6) , 3492-3502. https://doi.org/10.1021/acs.est.1c07362
14. Niepukolie Nipu, Lai Wei, Lauren Hamilton, Hyojin Lee, Jith Thomas, Jan A. Mennigen. Methylene blue at recommended concentrations alters metabolism in early zebrafish development. Communications Biology 2025, 8 (1) https://doi.org/10.1038/s42003-025-07471-8
15. Kruuttika M. Satbhai, Emily S. Marques, Ravi Ranjan, Alicia R. Timme-Laragy. Single-cell RNA sequencing reveals tissue-specific transcriptomic changes induced by perfluorooctanesulfonic acid (PFOS) in larval zebrafish (Danio rerio). Journal of Hazardous Materials 2025, 489 , 137515. https://doi.org/10.1016/j.jhazmat.2025.137515
16. Arian Farajizadeh, Lazarus Sui, Jonas Wong, Greg G. Goss. Modulation of PFOA (perfluorooctanoic acid) uptake in Daphnia (Daphnia magna) by TiO2 nanoparticles. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 2025, 291 , 110150. https://doi.org/10.1016/j.cbpc.2025.110150
17. William Johnston, Sally Adil, Catherine Cao, Niepukolie Nipu, Jan A. Mennigen. Fish models to explore epigenetic determinants of hypoxia-tolerance. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 2025, 302 , 111811. https://doi.org/10.1016/j.cbpa.2025.111811
18. Hongbo Yang, Chan Xu, Jieyu Song, Jin Li, Chan Zhang, Chunli Teng, Kai Ma, Feng Xie. Toxicokinetic and liver proteomic study of the Chinese rare minnow (Gobiocypris rarus) exposed to F-53B. Aquatic Toxicology 2025, 254 , 107312. https://doi.org/10.1016/j.aquatox.2025.107312
19. Fuyu Liu, Hui Xue, Tingshuo Kang, Qiupei Lei, Jiazhe Chen, Zhihong Zuo, Bin Han, Xize Lu, Xiao Yang, Xiangcheng Shan, Xiaoyang Song, Qingzhe Zhang, Yongguang Yin, Yong Cai. Efficient photodegradation of perfluoroalkyl substances under visible light by hexagonal ZnIn2S4 nanosheets. Journal of Environmental Sciences 2025, 148 , 116-125. https://doi.org/10.1016/j.jes.2024.01.014
20. Hana Mirmajidi, Hyojin Lee, Niepukolie Nipu, Jith Thomas, Zuzana Gajdosechova, David Kennedy, Jan A. Mennigen, Eva Hemmer. Nano-bio interactions of Gum Arabic-stabilized lanthanide-based upconverting nanoparticles: in vitro and in vivo study. Journal of Materials Chemistry B 2024, 13 (1) , 160-176. https://doi.org/10.1039/D4TB01579G
21. Fuyue Wang, Jiacheng Fang, Xiaoxiao Wang, Siyi Lin, Xiuli Su, Qingyuan Dai, Jing Zhang, Guodong Cao, Hong Yan, Zongwei Cai. Mechanistic insights into the neurotoxicity of F53B: Effects on metabolic dysregulation and apoptosis of dopaminergic neurons. Journal of Hazardous Materials 2024, 480 , 136306. https://doi.org/10.1016/j.jhazmat.2024.136306
22. Dandan Li, Chen Xie, Ziwu Fan, Rui Ding, Xiaoyu Wang, Yipeng Liao. Evidence that cadmium aggravate the toxicity of triphenyl phosphate in aquatic sediments to Corbicula fluminea. Journal of Hazardous Materials 2024, 480 , 136407. https://doi.org/10.1016/j.jhazmat.2024.136407
23. Zi-wei Chen, Zu-lin Hua. Effect of Co-exposure to Additional Substances on the Bioconcentration of Per(poly)fluoroalkyl Substances: A Meta-Analysis Based on Hydroponic Experimental Evidence. Archives of Environmental Contamination and Toxicology 2024, 87 (3) , 270-286. https://doi.org/10.1007/s00244-024-01087-5
24. Shuyan Xu, Pengfeng Zhu, Caiqin Wang, Daoyong Zhang, Ming Zhang, Xiangliang Pan. Nanoscale exopolymer reassembly-trap mechanism determines contrasting PFOS exposure patterns in aquatic animals with different feeding habitats: A nano-visualization study. Journal of Hazardous Materials 2024, 478 , 135515. https://doi.org/10.1016/j.jhazmat.2024.135515
25. Fan Yu, Jiaping Wu, Huangyingzi Wang, Yinzhou Bao, Haoyu Xing, Wenpei Ye, Xuhua Li, Manhong Huang. Interaction of microplastics with perfluoroalkyl and polyfluoroalkyl substances in water: A review of the fate, mechanisms and toxicity. Science of The Total Environment 2024, 948 , 175000. https://doi.org/10.1016/j.scitotenv.2024.175000
26. Yao Cheng, Yihan Hu, Keman Yu, Boning Zeng. Occurrence of legacy and Emerging per- and polyfluoroalkyl substances (PFASs) in indoor dust from office environment in south china. Emerging Contaminants 2024, 10 (3) , 100375. https://doi.org/10.1016/j.emcon.2024.100375
27. Han Zhang, Yinyin Zhang, Luxiang Zhu, Yanan Liu. Efficient degradation of F-53B as PFOS alternative in water by plasma discharge: Feasibility and mechanism insights. Journal of Hazardous Materials 2024, 476 , 135069. https://doi.org/10.1016/j.jhazmat.2024.135069
28. Shuai Liu, Yu Liu, Bin Tang, Qiyu Wang, Miao Zhang, Wenhui Qiu, Xiaojun Luo, Bixian Mai, Yujiang Hao, Jinsong Zheng, Kexiong Wang, Ding Wang. Spatial distribution, trophic magnification, and risk assessment of per- and polyfluoroalkyl substances in Yangtze finless porpoise (Neophocaena asiaeorientalis asiaeorientalis): Risks of emerging alternatives. Journal of Hazardous Materials 2024, 477 , 135246. https://doi.org/10.1016/j.jhazmat.2024.135246
29. Kai Wang, Lu He, Xiaoyu Liu, Mengfei Wu. Sodium p-perfluorinated noneoxybenzen sulfonate (OBS) induced neurotoxicity in zebrafish through mitochondrial dysfunction. Chemosphere 2024, 362 , 142651. https://doi.org/10.1016/j.chemosphere.2024.142651
30. Zi-wei Chen, Zu-lin Hua, Peng Guo. The bioaccumulation and ecotoxicity of co-exposure of per(poly)fluoroalkyl substances and polystyrene microplastics to Eichhornia crassipes. Water Research 2024, 260 , 121878. https://doi.org/10.1016/j.watres.2024.121878
31. Shenpan Li, LuYin Wu, HuiXian Zeng, Jing Zhang, ShuangJian Qin, Li-Xia Liang, John Andersson, Wen-Jie Meng, Xing-Yu Chen, Qi-Zhen Wu, Li-Zi Lin, Wei-Chun Chou, Guang-Hui Dong, Xiao-Wen Zeng. Hepatic injury and ileitis associated with gut microbiota dysbiosis in mice upon F–53B exposure. Environmental Research 2024, 248 , 118305. https://doi.org/10.1016/j.envres.2024.118305
32. Waldemar Studziński, Izabela Narloch, Łukasz Dąbrowski. Determination of the efficiency of electrolyzed water devices for the removal of pesticides in aqueous solutions and the characteristics of the pesticide residues and their transformation products. Journal of Water Process Engineering 2024, 61 , 105372. https://doi.org/10.1016/j.jwpe.2024.105372
33. Xiaohan Li, Qian Zhang, Aiqing Wang, Shan Shan, Xueying Wang, Yarong Wang, Jianmei Wan, Ping Ning, Chengjiao Hong, Hailin Tian, Yun Zhao. Hepatotoxicity induced in rats by chronic exposure to F–53B, an emerging replacement of perfluorooctane sulfonate (PFOS). Environmental Pollution 2024, 346 , 123544. https://doi.org/10.1016/j.envpol.2024.123544
34. Minfei Jian, Xi Chen, Shuai Liu, Yingxin Liu, Yu Liu, Qiyu Wang, Wenqing Tu. Combined exposure with microplastics increases the toxic effects of PFOS and its alternative F-53B in adult zebrafish. Science of The Total Environment 2024, 920 , 170948. https://doi.org/10.1016/j.scitotenv.2024.170948
35. Hui Qin, Yueming Lang, Yiteng Wang, Wei Cui, Yuxin Niu, Haiyang Luan, Minghan Li, Han Zhang, Shujing Li, Chenxi Wang, Wei Liu. Adipogenic and osteogenic effects of OBS and synergistic action with PFOS via PPARγ–RXRα heterodimers. Environment International 2024, 183 , 108354. https://doi.org/10.1016/j.envint.2023.108354
36. Lihui Zhao, Miaomiao Teng, Di Shi, Jiaqi Sun, Yunxia Li, Zixuan Zhang, Wentao Zhu, Fengchang Wu. Adverse impacts of environmentally relevant PFOS alternatives on mice pancreatic tissues. Science of The Total Environment 2024, 909 , 168649. https://doi.org/10.1016/j.scitotenv.2023.168649
37. Yilong Zou, Yu Zhou, Yulong Wu, Xianglian Wang, Guiqing Gao, Gang Chen, Zhanmeng Liu, Mi Deng, Xueping Huang, Yongming Wu. Toxicokinetics, Tissue Distribution, and Toxic Potency of Pfos Alternative Obs in Adult Zebrafish (Danio Rerio) Based on Flow-Through Exposure System. 2024https://doi.org/10.2139/ssrn.5061410
38. Wanying Gui, Hua Guo, Congcong Wang, Minjia Li, Yuanxiang Jin, Kun Zhang, Jiayin Dai, Yanbin Zhao. Comparative developmental toxicities of zebrafish towards structurally diverse per- and polyfluoroalkyl substances. Science of The Total Environment 2023, 902 , 166569. https://doi.org/10.1016/j.scitotenv.2023.166569
39. Pengyu Chen, Yuxi Hu, Geng Chen, Na Zhao, Zhichao Dou. Probing the bioconcentration and metabolism disruption of bisphenol A and its analogues in adult female zebrafish from integrated AutoQSAR and metabolomics studies. Science of The Total Environment 2023, 905 , 167011. https://doi.org/10.1016/j.scitotenv.2023.167011
40. Qiyu Wang, Yu Liu, Miao Zhang, Shuai Liu, Nannan Wan, Mingqi Li, Wenqing Tu. Novel PFOS alternative OBS inhibits body growth of developing zebrafish by triggering thyroid function disorder and osteoclast differentiation. Chemosphere 2023, 341 , 140068. https://doi.org/10.1016/j.chemosphere.2023.140068
41. Li-Xia Liang, Jingjing Liang, Qing-Qing Li, Mohammed Zeeshan, Zheqing Zhang, Nanxiang Jin, Li-Zi Lin, Lu-Yin Wu, Ming-Kun Sun, Wei-Hong Tan, Yang Zhou, Chu Chu, Li-Wen Hu, Ru-Qing Liu, Xiao-Wen Zeng, Yunjiang Yu, Guang-Hui Dong. Early life exposure to F-53B induces neurobehavioral changes in developing children and disturbs dopamine-dependent synaptic signaling in weaning mice. Environment International 2023, 181 , 108272. https://doi.org/10.1016/j.envint.2023.108272
42. Chu Chu, Qiu-Ling Fang, Xin-Xin Cui, Peng-Xin Dong, Zhengmin Qian, Stephen Edward McMillin, Steven W. Howard, Yan-Qiu Ou, Qing-Qing Li, Lu-Yin Wu, Li-Xia Liang, Shuang-Jian Qin, Xiao-Wen Zeng, Li-Wen Hu, Ming-Deng Xiang, Guang-Hui Dong, Xiao-Miao Zhao. Non-monotonic Association Between Chlorinated Polyfluorinated Ether Sulfonic Acids Exposure and the Risk of Overweight/Obesity Status in Adults. Exposure and Health 2023, 15 (3) , 539-549. https://doi.org/10.1007/s12403-022-00506-z
43. Zhaoyu Jiao, Nanyang Yu, Jiadi Mao, Qian Yang, Liping Jiao, Xuebing Wang, Wei Shi, Hongxia Yu, Si Wei. The occurrence, tissue distribution, and PBT potential of per- and polyfluoroalkyl substances in the freshwater organisms from the Yangtze river via nontarget analysis. Journal of Hazardous Materials 2023, 458 , 131868. https://doi.org/10.1016/j.jhazmat.2023.131868
44. Mengmeng Xu, Jessica Legradi, Pim Leonards. A comprehensive untargeted metabolomics study in zebrafish embryos exposed to perfluorohexane sulfonate (PFHxS). Science of The Total Environment 2023, 887 , 163770. https://doi.org/10.1016/j.scitotenv.2023.163770
45. Yvonne Rericha, Michael T Simonich, Lisa Truong, Robyn L Tanguay. Review of the zebrafish as a model to investigate per- and polyfluoroalkyl substance toxicity. Toxicological Sciences 2023, 194 (2) , 138-152. https://doi.org/10.1093/toxsci/kfad051
46. Dan Yang, Xiaohui Li, Shasha Dong, Xiaohui Zhao, Xiaoying Li, Meng Zhang, Yawei Shi, Guanghui Ding. Developmental Toxicity and Cardiotoxicity Induced by PFOS and its Novel Alternative OBS in Early Life Stage of Zebrafish (Danio rerio). Water, Air, & Soil Pollution 2023, 234 (7) https://doi.org/10.1007/s11270-023-06512-4
47. Dandan Gao, Chunmiao Kong, Hongping Liao, Muhammad Junaid, Ting Pan, Xikun Chen, Qiuping Wang, Xu Wang, Jun Wang. Interactive effects of polystyrene nanoplastics and 6:2 chlorinated polyfluorinated ether sulfonates on the histomorphology, oxidative stress and gut microbiota in Hainan Medaka (Oryzias curvinotus). Science of The Total Environment 2023, 880 , 163307. https://doi.org/10.1016/j.scitotenv.2023.163307
48. Yingxin Liu, Shuai Liu, Jing Huang, Yu Liu, Qiyu Wang, Jinyuan Chen, Liwei Sun, Wenqing Tu. Mitochondrial dysfunction in metabolic disorders induced by per- and polyfluoroalkyl substance mixtures in zebrafish larvae. Environment International 2023, 176 , 107977. https://doi.org/10.1016/j.envint.2023.107977
49. Michael Kalyn, Hyojin Lee, Jory Curry, Wenqing Tu, Marc Ekker, Jan A. Mennigen. Effects of PFOS, F-53B and OBS on locomotor behaviour, the dopaminergic system and mitochondrial function in developing zebrafish (Danio rerio). Environmental Pollution 2023, 326 , 121479. https://doi.org/10.1016/j.envpol.2023.121479
50. Pierre-André Billat, Carolina Vogs, Clément Blassiau, Céline Brochot, Emma Wincent, François Brion, Rémy Beaudouin. PBTK modeled perfluoroalkyl acid kinetics in zebrafish eleutheroembryos suggests impacts on bioconcentrations by chorion porosity dynamics. Toxicology in Vitro 2023, 89 , 105588. https://doi.org/10.1016/j.tiv.2023.105588
51. Lihui Zhao, Miaomiao Teng, Xiaoli Zhao, Yunxia Li, Jiaqi Sun, Wentian Zhao, Yuefei Ruan, Kenneth M.Y. Leung, Fengchang Wu. Insight into the binding model of per- and polyfluoroalkyl substances to proteins and membranes. Environment International 2023, 175 , 107951. https://doi.org/10.1016/j.envint.2023.107951
52. Miao Zhang, Xiaowen Bi, Shuai Liu, Yu Liu, Qiyu Wang. The novel polyfluoroalkyl benzenesulfonate OBS exposure induces cell cycle arrest and senescence of rat pituitary cell GH3 via the p53/p21/RB pathway. Toxicology 2023, 490 , 153511. https://doi.org/10.1016/j.tox.2023.153511
53. Qiyu Wang, Xueyan Gu, Yu Liu, Shuai Liu, Wuting Lu, Yongming Wu, Huiqiang Lu, Jing Huang, Wenqing Tu. Insights into the circadian rhythm alterations of the novel PFOS substitutes F-53B and OBS on adult zebrafish. Journal of Hazardous Materials 2023, 448 , 130959. https://doi.org/10.1016/j.jhazmat.2023.130959
54. Jingrun Hu, Yitao Lyu, Huan Chen, Leilei Cai, Jie Li, Xiaoqiang Cao, Weiling Sun. Integration of target, suspect, and nontarget screening with risk modeling for per- and polyfluoroalkyl substances prioritization in surface waters. Water Research 2023, 233 , 119735. https://doi.org/10.1016/j.watres.2023.119735
55. Bianhe Lu, Jin Qian, Jing Hu, Yuanyuan Huang, Peifang Wang, Junwei Shen, Yuxuan He, Sijing Tang, Yin Liu, Yuhang Zhang. Plant rhizosphere defense system respond differently to emerging polyfluoroalkyl substances F-53B and PFOS stress. Journal of Hazardous Materials 2023, 443 , 130119. https://doi.org/10.1016/j.jhazmat.2022.130119
56. Zhiyi Yang, Lei Fu, Mengxi Cao, Fang Li, Jingguang Li, Zhiyu Chen, Ang Guo, Huifang Zhong, Wenbo Li, Yong Liang, Qian Luo. PFAS-induced lipidomic dysregulations and their associations with developmental toxicity in zebrafish embryos. Science of The Total Environment 2023, 861 , 160691. https://doi.org/10.1016/j.scitotenv.2022.160691
57. Tingting Ma, Peng Wu, Lisha Wang, Quanguo Li, Xiuhua Li, Yongming Luo. Toxicity of per- and polyfluoroalkyl substances to aquatic vertebrates. Frontiers in Environmental Science 2023, 11 https://doi.org/10.3389/fenvs.2023.1101100
58. Demetri D. Spyropoulos. Metabolism disrupting chemicals in the development of human diseases. 2023, 163-177. https://doi.org/10.1016/B978-0-12-824464-7.00006-4
59. Michelle Huang, Emma Ivantsova, Isaac Konig, Neep Patel, Cole English, Christopher L. Souders, Christopher J. Martyniuk. Developmental and mitochondrial toxicity assessment of perfluoroheptanoic acid (PFHpA) in zebrafish (Danio rerio). Environmental Toxicology and Pharmacology 2023, 97 , 104037. https://doi.org/10.1016/j.etap.2022.104037
60. Mengmeng Xu, Jessica Legradi, Pim Leonards. A Comprehensive Untargeted Metabolomics Study of Perfluorohexane Sulfonate (Pfhxs) in Developing Zebrafish Embryos. 2023https://doi.org/10.2139/ssrn.4351067
61. Haixiang Cheng, Chenhan Lv, Jianhui Li, Dexin Wu, Xugang Zhan, Ying Song, Nan Zhao, Hangbiao Jin. Bioaccumulation and biomagnification of emerging poly- and perfluoroalkyl substances in marine organisms. Science of The Total Environment 2022, 851 , 158117. https://doi.org/10.1016/j.scitotenv.2022.158117
62. Shuyan Xu, Pengfeng Zhu, Caiqin Wang, Daoyong Zhang, Xiangliang Pan. Environmental concentration PFOS as a light shield for lake exopolymers against photodegradation by formation of sandwiched supramolecular nanostructures. Water Research 2022, 227 , 119345. https://doi.org/10.1016/j.watres.2022.119345
63. Min Nian, Wei Zhou, Yan Feng, Yan Wang, Qian Chen, Jun Zhang. Emerging and legacy PFAS and cytokine homeostasis in women of childbearing age. Scientific Reports 2022, 12 (1) https://doi.org/10.1038/s41598-022-10501-8
64. David J. Beale, Georgia M. Sinclair, Rohan Shah, Amy M. Paten, Anupama Kumar, Sara M. Long, Suzanne Vardy, Oliver A.H. Jones. A review of omics-based PFAS exposure studies reveals common biochemical response pathways. Science of The Total Environment 2022, 845 , 157255. https://doi.org/10.1016/j.scitotenv.2022.157255
65. Yanhui Dai, Jian Zhao, Chunxiao Sun, Diying Li, Xia Liu, Zhenyu Wang, Tongtao Yue, Baoshan Xing. Interaction and combined toxicity of microplastics and per- and polyfluoroalkyl substances in aquatic environment. Frontiers of Environmental Science & Engineering 2022, 16 (10) https://doi.org/10.1007/s11783-022-1571-2
66. Jing Huang, Yu Liu, Qiyu Wang, Jianfeng Yi, Hong Lai, Liwei Sun, Jan Alexander Mennigen, Wenqing Tu. Concentration-dependent toxicokinetics of novel PFOS alternatives and their chronic combined toxicity in adult zebrafish. Science of The Total Environment 2022, 839 , 156388. https://doi.org/10.1016/j.scitotenv.2022.156388
67. Shangyi Li, Mengbin Gu, Jun Huang, Yujue Wang, Gang Yu. Oligolayered Co@MXene with a Co···SO3 cation-π bridge for ultra-rapid catalytic oxidation of a novel “forever chemical” OBS. Applied Catalysis B: Environmental 2022, 311 , 121364. https://doi.org/10.1016/j.apcatb.2022.121364
68. Qiyu Wang, Jing Huang, Shuai Liu, Caiyun Wang, Yuanxiang Jin, Hong Lai, Wenqing Tu. Aberrant hepatic lipid metabolism associated with gut microbiota dysbiosis triggers hepatotoxicity of novel PFOS alternatives in adult zebrafish. Environment International 2022, 166 , 107351. https://doi.org/10.1016/j.envint.2022.107351
69. Longfei Zhou, Sisi He, Yali Shi, Yaqi Cai, Chunhui Zhang. Tissue distribution of sodium p-perfluorous nonenoxybenzene sulfonate (OBS) in mice via oral exposure. Environment International 2022, 165 , 107289. https://doi.org/10.1016/j.envint.2022.107289
70. Luyin Wu, Yao Dang, Li-Xia Liang, Yan-Chen Gong, Mohammed Zeeshan, Zhengmin Qian, Sarah Dee Geiger, Michael G. Vaughn, Yang Zhou, Qing-Qing Li, Chu Chu, Ya-Wen Tan, Li-Zi Lin, Ru-Qing Liu, Li-Wen Hu, Bo-Yi Yang, Xiao-Wen Zeng, Yunjiang Yu, Guang-Hui Dong. Perfluorooctane sulfonates induces neurobehavioral changes and increases dopamine neurotransmitter levels in zebrafish larvae. Chemosphere 2022, 297 , 134234. https://doi.org/10.1016/j.chemosphere.2022.134234
71. Nicolas Macorps, Karyn Le Menach, Patrick Pardon, Sabrina Guérin-Rechdaoui, Vincent Rocher, Hélène Budzinski, Pierre Labadie. Bioaccumulation of per- and polyfluoroalkyl substance in fish from an urban river: Occurrence, patterns and investigation of potential ecological drivers. Environmental Pollution 2022, 303 , 119165. https://doi.org/10.1016/j.envpol.2022.119165
72. Bernard Robaire, Geraldine Delbes, Jessica A. Head, Vicki L. Marlatt, Christopher J. Martyniuk, Stéphane Reynaud, Vance L. Trudeau, Jan A. Mennigen. A cross-species comparative approach to assessing multi- and transgenerational effects of endocrine disrupting chemicals. Environmental Research 2022, 204 , 112063. https://doi.org/10.1016/j.envres.2021.112063
73. Jing Huang, Qiyu Wang, Shuai Liu, Hong Lai, Wenqing Tu. Comparative chronic toxicities of PFOS and its novel alternatives on the immune system associated with intestinal microbiota dysbiosis in adult zebrafish. Journal of Hazardous Materials 2022, 425 , 127950. https://doi.org/10.1016/j.jhazmat.2021.127950
74. Raphaël Chackal, Tyler Eng, Emille M. Rodrigues, Sara Matthews, Florence Pagé-Lariviére, Stephanie Avery-Gomm, Elvis Genbo Xu, Nathalie Tufenkji, Eva Hemmer, Jan A. Mennigen. Metabolic Consequences of Developmental Exposure to Polystyrene Nanoplastics, the Flame Retardant BDE-47 and Their Combination in Zebrafish. Frontiers in Pharmacology 2022, 13 https://doi.org/10.3389/fphar.2022.822111
75. Yun-Ting Zhang, Mohammed Zeeshan, Fan Su, Zheng-Min Qian, Sarah Dee Geiger, Stephen Edward McMillin, Zhi-Bin Wang, Peng-Xin Dong, Yan-Qiu Ou, Shi-Min Xiong, Xu-Bo Shen, Pei-En Zhou, Bo-Yi Yang, Chu Chu, Qing-Qing Li, Xiao-Wen Zeng, Wen-Ru Feng, Yuan-Zhong Zhou, Guang-Hui Dong. Associations between both legacy and alternative per- and polyfluoroalkyl substances and glucose-homeostasis: The Isomers of C8 health project in China. Environment International 2022, 158 , 106913. https://doi.org/10.1016/j.envint.2021.106913
76. Caiyun Wang, You Weng, Wenqing Tu, Cuiyuan Jin, Yuanxiang Jin. Maternal exposure to sodium ρ-perfluorous nonenoxybenzene sulfonate during pregnancy and lactation disrupts intestinal barrier and may cause obstacles to the nutrient transport and metabolism in F0 and F1 generations of mice. Science of The Total Environment 2021, 794 , 148775. https://doi.org/10.1016/j.scitotenv.2021.148775
77. Shuai Liu, Hong Lai, Qiyu Wang, Rubén Martínez, Miao Zhang, Yu Liu, Jing Huang, Mi Deng, Wenqing Tu. Immunotoxicity of F 53B, an alternative to PFOS, on zebrafish (Danio rerio) at different early life stages. Science of The Total Environment 2021, 790 , 148165. https://doi.org/10.1016/j.scitotenv.2021.148165
78. Guochun Lv, Xiaomin Sun. The molecular-level understanding of the uptake of PFOS and its alternatives (6:2 Cl-PFESA and OBS) into phospholipid bilayers. Journal of Hazardous Materials 2021, 417 , 125991. https://doi.org/10.1016/j.jhazmat.2021.125991
79. Jing Huang, Qiyu Wang, Shuai Liu, Miao Zhang, Yu Liu, Liwei Sun, Yongming Wu, Wenqing Tu. Crosstalk between histological alterations, oxidative stress and immune aberrations of the emerging PFOS alternative OBS in developing zebrafish. Science of The Total Environment 2021, 774 , 145443. https://doi.org/10.1016/j.scitotenv.2021.145443
80. Dario Savoca, Andrea Pace. Bioaccumulation, Biodistribution, Toxicology and Biomonitoring of Organofluorine Compounds in Aquatic Organisms. International Journal of Molecular Sciences 2021, 22 (12) , 6276. https://doi.org/10.3390/ijms22126276
81. Jing Huang, Liwei Sun, Jan Alexander Mennigen, Yu Liu, Shuai Liu, Miao Zhang, Qiyu Wang, Wenqing Tu. Developmental toxicity of the novel PFOS alternative OBS in developing zebrafish: An emphasis on cilia disruption. Journal of Hazardous Materials 2021, 409 , 124491. https://doi.org/10.1016/j.jhazmat.2020.124491
82. Yilong Zou, Yongming Wu, Qiyu Wang, Jinbao Wan, Mi Deng, Wenqing Tu. Comparison of toxicokinetics and toxic effects of PFOS and its novel alternative OBS in zebrafish larvae. Chemosphere 2021, 265 , 129116. https://doi.org/10.1016/j.chemosphere.2020.129116
83. Waldemar Studziński, Alicja Gackowska, Edyta Kudlek. Determination of environmental properties and toxicity of octyl-dimethyl-para-aminobenzoic acid and its degradation products. Journal of Hazardous Materials 2021, 403 , 123856. https://doi.org/10.1016/j.jhazmat.2020.123856
84. Caiyun Wang, Cuiyuan Jin, Wenqing Tu, Yuanxiang Jin. Maternal exposure of mice to sodium p-perfluorous nonenoxybenzene sulfonate causes endocrine disruption in both dams and offspring. Endocrine Journal 2021, 68 (10) , 1165-1177. https://doi.org/10.1507/endocrj.EJ20-0781
85. Rubén Martínez, Anna E. Codina, Carlos Barata, Romà Tauler, Benjamin Piña, Laia Navarro-Martín. Transcriptomic effects of tributyltin (TBT) in zebrafish eleutheroembryos. A functional benchmark dose analysis. Journal of Hazardous Materials 2020, 398 , 122881. https://doi.org/10.1016/j.jhazmat.2020.122881
86. J. Erik Mylroie, Mitchell S. Wilbanks, Ashley N. Kimble, Kimberly T. To, Catherine S. Cox, Sheila J. McLeod, Kurt A. Gust, David W. Moore, Edward J. Perkins, Natàlia Garcia-Reyero. Perfluorooctanesulfonic Acid–Induced Toxicity on Zebrafish Embryos in the Presence or Absence of the Chorion. Environmental Toxicology and Chemistry 2020, 40 (3) , 780-791. https://doi.org/10.1002/etc.4899
87. Rubén Martínez, Wenqing Tu, Tyler Eng, Melissa Allaire-Leung, Benjamin Piña, Laia Navarro-Martín, Jan A. Mennigen. Acute and long-term metabolic consequences of early developmental Bisphenol A exposure in zebrafish (Danio rerio). Chemosphere 2020, 256 , 127080. https://doi.org/10.1016/j.chemosphere.2020.127080
88. Huilin Yang, Hong Lai, Jing Huang, Liwei Sun, Jan Alexander Mennigen, Qiyu Wang, Yu Liu, Yuanxiang Jin, Wenqing Tu. Polystyrene microplastics decrease F–53B bioaccumulation but induce inflammatory stress in larval zebrafish. Chemosphere 2020, 255 , 127040. https://doi.org/10.1016/j.chemosphere.2020.127040
89. Bo Zhang, Yuan He, Yingyan Huang, Danhong Hong, Yiming Yao, Lei Wang, Wenwen Sun, Baoqin Yang, Xiongfei Huang, Shiming Song, Xueyuan Bai, Yuankai Guo, Tao Zhang, Hongwen Sun. Novel and legacy poly- and perfluoroalkyl substances (PFASs) in indoor dust from urban, industrial, and e-waste dismantling areas: The emergence of PFAS alternatives in China. Environmental Pollution 2020, 263 , 114461. https://doi.org/10.1016/j.envpol.2020.114461
90. Abeer A. Banjabi, Adela Jing Li, Taha A. Kumosani, Jehad M. Yousef, Kurunthachalam Kannan. Serum concentrations of perfluoroalkyl substances and their association with osteoporosis in a population in Jeddah, Saudi Arabia. Environmental Research 2020, 187 , 109676. https://doi.org/10.1016/j.envres.2020.109676
91. Caiyun Wang, Yao Zhao, Yuanxiang Jin. The emerging PFOS alternative OBS exposure induced gut microbiota dysbiosis and hepatic metabolism disorder in adult zebrafish. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 2020, 230 , 108703. https://doi.org/10.1016/j.cbpc.2020.108703
92. Yali Shi, Xiaowei Song, Qi Jin, Wenhui Li, Sisi He, Yaqi Cai. Tissue distribution and bioaccumulation of a novel polyfluoroalkyl benzenesulfonate in crucian carp. Environment International 2020, 135 , 105418. https://doi.org/10.1016/j.envint.2019.105418