ACS Publications. Most Trusted. Most Cited. Most Read
Novel indolodioxanes with antihypertensive effects: potent ligands for the 5-HT1A receptor
My Activity
    Letter

    Novel indolodioxanes with antihypertensive effects: potent ligands for the 5-HT1A receptor
    Click to copy article linkArticle link copied!

    ACS Legacy Archive
    Other Access Options

    Journal of Medicinal Chemistry

    Cite this: J. Med. Chem. 1992, 35, 16, 3058–3066
    Click to copy citationCitation copied!
    https://doi.org/10.1021/jm00094a021
    Published August 1, 1992

    Note: In lieu of an abstract, this is the article's first page.

    Free first page

    Read this article

    To access this article, please review the available access options below.

    Get instant access

    Purchase Access

    Read this article for 48 hours. Check out below using your ACS ID or as a guest.

    Recommended

    Access through Your Institution

    You may have access to this article through your institution.

    Your institution does not have access to this content. Add or change your institution or let them know you’d like them to include access.

    Cited By

    Click to copy section linkSection link copied!
    Citation Statements
    Explore this article's citation statements on scite.ai

    This article is cited by 14 publications.

    1. Junghyun Chae and, Stephen L. Buchwald. Palladium-Catalyzed Regioselective Hydrodebromination of Dibromoindoles:  Application to the Enantioselective Synthesis of Indolodioxane U86192A. The Journal of Organic Chemistry 2004, 69 (10) , 3336-3339. https://doi.org/10.1021/jo035819k
    2. Rébecca Poulain,, Dragos Horvath,, Béatrice Bonnet,, Christian Eckhoff,, Béatrice Chapelain,, Marie-Christine Bodinier, and, Benoît Déprez. From Hit to Lead. Combining Two Complementary Methods for Focused Library Design. Application to μ Opiate Ligands. Journal of Medicinal Chemistry 2001, 44 (21) , 3378-3390. https://doi.org/10.1021/jm010877o
    3. Ruth E. TenBrink,, Carol L. Bergh,, J. Neil Duncan,, Douglas W. Harris,, R. M. Huff,, Robert A. Lahti,, Charles F. Lawson,, Barry S. Lutzke,, Iain J. Martin,, Susan A. Rees,, Siusaidh K. Schlachter,, John C. Sih, and, Martin W. Smith. (S)-(−)-4-[4-[2-(Isochroman-1-yl)ethyl]piperazin-1-yl]benzenesulfonamide, a Selective Dopamine D4 Antagonist. Journal of Medicinal Chemistry 1996, 39 (13) , 2435-2437. https://doi.org/10.1021/jm960084f
    4. William F. Berkowitz, Stuart W. McCombie. Cyclization of Vinyl and Aryl Azides into Pyrroles, Indoles, Carbazoles, and Related Fused Pyrroles. 2017, 1-170. https://doi.org/10.1002/0471264180.or092.02
    5. Stanislas Mayer, Jean-Yves Mérour, Benoît Joseph, Gérald Guillaumet. Synthesis and Reactivity of 1,4-Oxazinoindole Derivatives. European Journal of Organic Chemistry 2002, 2002 (10) , 1646-1653. https://doi.org/10.1002/1099-0690(200205)2002:10<1646::AID-EJOC1646>3.0.CO;2-K
    6. Richard E. Mewshaw, Karen L. Marquis, Xiaojie Shi, Georgia McGaughey, Gary Stack, Michael B. Webb, Magid Abou-Gharbia, Theodore Wasik, Rosemary Scerni, Taylor Spangler, Julie A. Brennan, Hossein Mazandarani, Joseph Coupet, Terrance H. Andree. New generation dopaminergic agents 4. Exploiting the 2-methyl chroman scaffold. Synthesis and evaluation of two novel series of 2-(aminomethyl)-3,4,7,9-tetrahydro-2H-pyrano[2,3-e]indole and indol-8-one derivatives. Tetrahedron 1998, 54 (25) , 7081-7108. https://doi.org/10.1016/S0040-4020(98)00349-4
    7. Michael P. Groziak, Frederick G. Jacobs. Tricyclic Systems: Central Carbocyclic Ring with Fused Five- and Six-membered Rings. 1996, 875-919. https://doi.org/10.1016/B978-008096518-5.00166-0
    8. . Volume 7 References. 1996, 947-1044. https://doi.org/10.1016/B978-008096518-5.00253-7
    9. R.J. Sundberg. Category Ii Cyclization—The Hemetsberger Synthesis. 1996, 45-47. https://doi.org/10.1016/B978-012676945-6/50025-9
    10. Shikai Zhao, Jeremiah P. Freeman, Philip F. VonVoigtlander, Martin W. Smith, Jacob Szmuszkovicz. Phenalene analogs of the kappa opiate agonist, U-50,488. Bioorganic & Medicinal Chemistry Letters 1993, 3 (12) , 2641-2646. https://doi.org/10.1016/S0960-894X(01)80733-2
    11. Michael D. Ennis, Robert L. Hoffman, Robert A. Lahti. 4-Aminomethyl chromans: dependence of serotonin and dopamine binding upon aromatic ring substitution. Bioorganic & Medicinal Chemistry Letters 1993, 3 (6) , 1131-1136. https://doi.org/10.1016/S0960-894X(00)80301-7
    12. Jens Perregaard, Connie Sánchez, Jørn Arnt. Overview: Recent Developments in Anxiolytics. Current Opinion on Therapeutic Patents 1993, 3 (1) , 101-128. https://doi.org/10.1517/13543776.3.1.101
    13. M. D. ENNIS, M. E. BAZE, M. W. SMITH, C. F. LAWSON, R. B. MCCALL, R. A. LAHTI, M. F. PIERCEY. ChemInform Abstract: Novel Indolodioxanes with Antihypertensive Effects: Potent Ligands for the 5‐HT1A Receptor.. ChemInform 1992, 23 (52) https://doi.org/10.1002/chin.199252206
    14. Nurullah Saracoglu. Functionalization of Indole and Pyrrole Cores via Michael-Type Additions. , 1-61. https://doi.org/10.1007/7081_2007_073

    Journal of Medicinal Chemistry

    Cite this: J. Med. Chem. 1992, 35, 16, 3058–3066
    Click to copy citationCitation copied!
    https://doi.org/10.1021/jm00094a021
    Published August 1, 1992

    Article Views

    171

    Altmetric

    -

    Citations

    Learn about these metrics

    Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.

    Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.

    The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated.