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Unusual Approach to Branched 3-Alkynylamides and to 1,5-Dihydropyrrol-2-ones

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    Unusual Approach to Branched 3-Alkynylamides and to 1,5-Dihydropyrrol-2-ones
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    Laboratoire de Synthèse Organique, CNRS UMR 7652, Ecole Polytechnique, 91128 Palaiseau Cedex, France
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    Organic Letters

    Cite this: Org. Lett. 2010, 12, 3, 416–419
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    https://doi.org/10.1021/ol902472r
    Published January 12, 2010
    Copyright © 2010 American Chemical Society
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    Abstract

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    Rare carboxamide branched alkynes such as 11a can be readily obtained by reaction of the electrophilic 4-alkylidene isoxazolinones with isocycanides followed by nitrosative cleavage of the heterocyclic ring. N-Iodosuccinimide induced ring closure in the presence of a nucleophile results in the formation of new iodopyrrolinones such as 16c.

    Copyright © 2010 American Chemical Society

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    38. Igor Dias‐Jurberg, Fabien Gagosz, Samir Z. Zard. ChemInform Abstract: Unusual Approach to Branched 3‐Alkynylamides and to 1,5‐Dihydropyrrol‐2‐ones.. ChemInform 2010, 41 (27) https://doi.org/10.1002/chin.201027120
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    Organic Letters

    Cite this: Org. Lett. 2010, 12, 3, 416–419
    Click to copy citationCitation copied!
    https://doi.org/10.1021/ol902472r
    Published January 12, 2010
    Copyright © 2010 American Chemical Society
    Request reuse permissions

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