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Physical Organic Chemistry: Never Out of Style
This Special Issue will showcase the breadth of modern physical organic chemistry and aim to highlight the numerous ways research in this area is helping to define the frontiers of our discipline.
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Next-Generation Cross-Coupling Chemistry
The construction of bonds between C atoms and biologically relevant elements such as C, O, N, S, and P (among others) is a fundamental goal of synthetic organic chemists. This Special Issue highlights the latest developments in next-generation cross-coupling chemistry.
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Next-Generation Organic Chemistry for Labeling and Imaging
This introductory editorial from the special issue dedicated to Next-Generation Organic Chemistry for Labeling and Imaging reflects the diverse ways in which organic chemistry is impacting biology, with applications that include fluorescence live cell imaging, single-molecule spectroscopy, high-throughput screening, in vivo fluorescence imaging, and radiology.
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JOCSynopses and Perspectives
The Editor-in-Chief of JOC identifies key areas and thought leaders in the field to invite brief focused reviews (as JOCSynopses) or personal overviews of specialized research areas (as Perspectives).
Exceptions, Paradoxes, and Their Resolutions in Chemical Reactivity
![Computational Analysis of Diastereoselectivity and Carbene Reactivity in Pt- and Au-Catalyzed 1,5-Enyne Cycloisomerization to Bicyclo[3.1.0]hexane](/cms/10.1021/acs.joc.4c02626/asset/images/medium/jo4c02626_0009.gif)
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![Iridium-Catalyzed Asymmetric Hydrogenation of Heteroaromatics with Multiple N Atoms via Substrate Activation: An Entry to 4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrimidine-3-carbonitrile Core of a Potent BTK Inhibitor](/cms/10.1021/acs.joc.3c02396/asset/images/medium/jo3c02396_0011.gif)
