ACS Publications. Most Trusted. Most Cited. Most Read
My Activity
Cover
Volume 27Issue 19

May 16, 2025

Submit ManuscriptGet Access

ASAP Articles are edited and published online ahead of issue. See all articles.

Announcements

Psychedelics and Entactogens Cover image

Open Call for Papers

π-Conjugated Molecules & Materials

This Special Issue will highlight the frontiers of research on organic π-systems/structures. The broad scope of the field will be encompassed by this Special Issue soliciting papers on synthetic methodology, design, and/or applications of π-systems/structures.
Learn More & Submit Your Manuscript
Deadline to Submit: July 1, 2025

Associate Editor Chunyan Chi is handling this special issue with support from Guest Editors Qian Miao, Araceli G. Campana, and Hiroshi Shinokubo.

lectureship award

Outstanding Publication of the Year Award

Congratulations Dr. Gabriel Schäfer and colleagues!

Organic Letters, in partnership with the ACS Division of Organic Chemistry, is proud to announce the winners of the 2025 Organic Letters Outstanding Publication of the Year Lectureship Award: Dr. Gabriel Schäfer and colleagues.

Learn more about their award-winning work

Featured Content

Recent highlights from the journal.

Gold-Mediated Chemistry Cover Image

Special Issues

Gold-Mediated Chemistry

The unique π-activation ability of gold has long served as the trademark for gold-catalyzed reactions. The broad reactivity platform exhibited by gold complexes exemplifies its potential for significant applications in total synthesis of highly functionalized compounds and even complex natural products. Organic Letters celebrates the value of gold in organic transformations with this Special Issue.

Negative Data in Data Sets for Machine Learning Training. ACS Publications. Most Trusted. Most Cited. Most Read.

Editorials

On the Integrity of Accurate Mass Measurement Data in Compound Characterization

Publications in chemistry contain vast amounts of data. Research relies heavily on reproducibility; therefore, inconsistent or invalid data can hinder scientific progress. These issues underscore the importance of ensuring high data quality, particularly when sharing work among the scientific community.

Dark grid material with hexagons and metallic balls rolling out of focus

Collections

Advancing Organic Chemistry in China: Sustainability, Precision, and Empowerment

Following up on our 2020 China Collection, Organic Letters is highlighting 36 Letters published in 2024 by Chinese chemists at the forefront of the field.

View the 2025 China Collection
Read the accompanying ACS Axial post

View all Collections from Organic Letters

Current Issue

The latest published issue of Organic Letters. See all articles.

Stay Connected...

Keep current with the latest ASAPs via e-alerts, and follow us for updates on conferences, research highlights, and more.

Get e-Alerts

Follow Us Online

Browse by Subject

Select a subject area to discover related terms and applicable articles.

All Subject Areas

See All (522439)

Most Read

Rankings are updated daily for previous 30 days (below) and previous 12 months. See all articles.

Advance your career with professional development resources, educational tools, free access to 50 ACS journal articles, and more!
Join ACS

Researchers

Discover our blog, and stay current with your field.

Authors

Everything you need to prepare and track your manuscript.

Reviewers

A free peer-review training course from ACS experts.

Organizations

Institutional information about ACS products and services.

Chemical & Engineering News


ACS Axial