Editor-in-Chief
- Christa E. Müller
- Full Professor of Pharmaceutical Chemistry
- PharmaCenter Bonn
- Pharmaceutical Institute
- Pharmaceutical & Medicinal Chemistry
- An der Immenburg 4, D-53121 Bonn, Germany
- Phone: +49-(0)228-73 2301
- Fax: +49-(0)228-732567
- Email: [email protected]
Awards & Accolades
- 2010 PHOENIX Science Award in Pharmacy/Pharmaceutical Chemistry
- 2011 and 2015 Research Prizes of Alzheimer Forschung Initiative e.V.
- 2012, 2013, 2014 Neuroallianz Publication Award in Gold (2013, 2014) and in Silver (2012, 2013, 2014)
- 2013 Prize for Inventors by the Ministry of North-Rhine Westfalia
- 2018 Nauta Award for Medicinal Chemistry and Chemical Biology of the European Federation of Medicinal Chemistry
- 2019 Tony Holy Lecture Award, Prague, Czech Republic
Research
The Müller group studies medicinal chemistry and pharmacology of purine binding membrane proteins (purine/pyrimidine receptors and ecto-nucleotidases), lipid-activated and orphan G protein-coupled receptors and G proteins. Recently, she started a project on the development of coronavirus therapeutics.
Biography
Prof. Dr. Christa Müller is a Full Professor of Pharmaceutical Chemistry and Director of the PharmaCenter Bonn, which she co-founded, at the University of Bonn (Germany). She received her Ph.D. in Pharmaceutical Chemistry from the University of Tübingen and then worked as an exchange scientist in the laboratory of Dr. John W. Daly at the Laboratory of Bioorganic Chemistry at the National Institutes of Health. In 1994, Christa started her independent career as an Associate Professor of pharmaceutical chemistry at the University of Würzburg and subsequently became a full Professor at the University of Bonn in 1998. In 2007, she co-founded the PharmaCenterBonn (PZB) and has served as the Director or alternating Deputy Director since then. Between 2010 and 2015, Christa fulfilled the role of Vice-Rector for Public and International Relations at the University of Bonn. In 2020, she joined the German Research Council review board for pharmacy and became Vice-President for Research of the German Pharmaceutical Society (DPhG). Christa is an author on over 400 original research articles and is a co-inventor on a number of patents or patent applications.
Current Research
Die Hauptprotease von SARS‐CoV‐2 als Zielstruktur: Von der Etablierung eines Hochdurchsatz‐Screenings zum Design maßgeschneiderter Inhibitoren
Julian Breidenbach, Carina Lemke, Dr. Thanigaimalai Pillaiyar, Laura Schäkel, Ghazl Al Hamwi, Miriam Diett, Robin Gedschold, Nina Geiger, Vittoria Lopez, Salahuddin Mirza, Dr. Vigneshwaran Namasivayam, Dr. Anke C. Schiedel, Katharina Sylvester, Dr. Dominik Thimm, Christin Vielmuth, Lan Phuong Vu, Maria Zyulina, Prof. Dr. Jochen Bodem, Prof. Dr. Michael Gütschow, Prof. Dr. Christa E. Müller
Cell‐permeable high‐affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors
Markus Kuschak, Vigneshwaran Namasivayam, Muhammad Rafehi, Jan H. Voss, Jaspal Garg, Jonathan G. Schlegel, Aliaa Abdelrahman, Stefan Kehraus, Raphael Reher, Jim Küppers, Katharina Sylvester, Sonja Hinz, Michaela Matthey, Daniela Wenzel, Bernd K. Fleischmann, Alexander Pfeifer, Asuka Inoue, Michael Gütschow, Gabriele M. König, Christa E. Müller
Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists
Tobias Claff, Jing Yu, Véronique Blais, Nilkanth Patel, Charlotte Martin, Lijie Wu, Gye Won Han, Brian J. Holleran, Olivier Van der Poorten, Kate L. White, Michael A. Hanson, Philippe Sarret, Louis Gendron, Vadim Cherezov, Vsevolod Katritch, Steven Ballet, Zhi-Jie Liu, Christa E. Müller and Raymond C. Stevens